ChemicalBook >> CAS DataBase List >>N-(Azido-PEG3)-N-Boc-PEG4-NHS ester

N-(Azido-PEG3)-N-Boc-PEG4-NHS ester

CAS No.
2112731-96-9
Chemical Name:
N-(Azido-PEG3)-N-Boc-PEG4-NHS ester
Synonyms
HUN 31969;N3-PEG4-Boc-PEG4-SPA;N-(Azido-PEG4)-N-Boc-PEG4-NHS ester;N-(Azido-PEG3)-N-Boc-PEG4-NHS ester
CBNumber:
CB03373695
Molecular Formula:
C28H49N5O13
Molecular Weight:
663.71436
MDL Number:
MFCD30723220
MOL File:
2112731-96-9.mol
MSDS File:
SDS
Last updated:2026-05-27 17:38:00

N-(Azido-PEG3)-N-Boc-PEG4-NHS ester Properties

storage temp. -20°C, sealed storage, away from moisture
form Liquid
color Colorless to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Danger
Hazard statements  H225
Precautionary statements  P501-P240-P210-P233-P243-P241-P242-P280-P370+P378-P303+P361+P353-P403+P235

N-(Azido-PEG3)-N-Boc-PEG4-NHS ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0107151 N-(Azido-PEG4)-N-Boc-PEG4-NHS ester ≥95% 2112731-96-9 100mg $532 2026-06-04 Buy
ChemScene CS-0107151 N-(Azido-PEG4)-N-Boc-PEG4-NHS ester ≥95% 2112731-96-9 250mg $911 2026-06-04 Buy
ChemScene CS-0107151 N-(Azido-PEG4)-N-Boc-PEG4-NHS ester ≥95% 2112731-96-9 1g $3644 2026-06-04 Buy
BroadPharm bp-23586 N-(Azido-PEG3)-N-Boc-PEG4-NHS ester 95% 2112731-96-9 100MG $330 2026-05-24 Buy
BroadPharm bp-23586 N-(Azido-PEG3)-N-Boc-PEG4-NHS ester 95% 2112731-96-9 250MG $570 2026-05-24 Buy
Product number Packaging Price Buy
CS-0107151 100mg $532 Buy
CS-0107151 250mg $911 Buy
CS-0107151 1g $3644 Buy
bp-23586 100MG $330 Buy
bp-23586 250MG $570 Buy

N-(Azido-PEG3)-N-Boc-PEG4-NHS ester Chemical Properties, Uses, Production

Description

N-(Azido-PEG3)-N-Boc-PEG4-NHS ester is a branched PEGylation reagent with a terminal azide group (N3), a Boc protected amine (NH2), and a terminal NHS ester.The azide group enables PEGylation via Click Chemistry. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The protected amine can be deprotected under acidic conditions.

Uses

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs[1] N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23. DOI:10.1016/j.jconrel.2016.02.017

N-(Azido-PEG3)-N-Boc-PEG4-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

N-(Azido-PEG3)-N-Boc-PEG4-NHS ester Suppliers

Global Suppliers ( 18)
Supplier Tel Email Country ProdList Advantage
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80534353 19917294565 et@chemextension.com China 3904 55
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Minhan Pharmaceutical Technology Co., Ltd. 17612188245 2816925681@qq.com China 8316 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Nantong Hanfang Biotechnology Co. , Ltd. hanfangpharma@126.com 18017580634 hanfangpharma@126.com China 25800 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Suzhou Derivative Biotechnology Co., Ltd. 13915541704 2436368162@qq.com China 707 58

View Latest Price from N-(Azido-PEG3)-N-Boc-PEG4-NHS ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-(Azido-PEG3)-N-Boc-PEG4-NHS ester pictures 2025-06-07 N-(Azido-PEG3)-N-Boc-PEG4-NHS ester
2112731-96-9
500mg >95.00% 500mg Xian confluore Biological Technology Co., Ltd.
N-(Azido-PEG3)-N-Boc-PEG4-NHS ester N-(Azido-PEG4)-N-Boc-PEG4-NHS ester HUN 31969 N3-PEG4-Boc-PEG4-SPA 2112731-96-9