ChemicalBook >> CAS DataBase List >>1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride structure

CAS No.: 1620278-72-9

Chemical Name:: 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride

Synonyms: TLR7/8 agonist-5d;TLR7/8 agonist 1 2HCl;8 agonist 1 dihydrochloride;TLR7/8 Agonist 1 (hydrochloride);TLR7/8 Agonist 5d (hydrochloride);TLR7/8 agonist 1 (dihydrochloride);TLR7/8 agonist 1 dihydrochloride, 10 mM in DMSO;1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride;Toll-like Receptor (TLR),TLR7/8 agonist 1,TLR7/8 agonist 1 dihydrochloride,TLR-7/8 agonist 1 dihydrochloride,Inhibitor,inhibit

CBNumber:: CB03374339

Molecular Formula:: C22H26ClN5

Molecular Weight:: 395.94

MDL Number:: MFCD31657341

MOL File:: 1620278-72-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 17:38:06

Request For Quotation

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Properties

storage temp.	Store at -20°C
solubility	DMSO:83.33(Max Conc. mg/mL);192.72(Max Conc. mM)
form	A solid
color	Off-white to light yellow
InChI	InChI=1S/C22H25N5.ClH/c1-2-3-8-19-26-20-21(17-6-4-5-7-18(17)25-22(20)24)27(19)14-16-11-9-15(13-23)10-12-16;/h4-7,9-12H,2-3,8,13-14,23H2,1H3,(H2,24,25);1H
InChIKey	IIFIHBPSMOIXGG-UHFFFAOYSA-N
SMILES	C(C1C=CC(CN)=CC=1)N1C(=NC2C(N)=NC3=CC=CC=C3C1=2)CCCC.Cl

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	28451	TLR7/8 Agonist 1 (hydrochloride) ≥98%	1620278-72-9	500μg	$81	2026-04-30	Buy
Cayman Chemical	28451	TLR7/8 Agonist 1 (hydrochloride) ≥98%	1620278-72-9	1mg	$145	2026-04-30	Buy
Cayman Chemical	28451	TLR7/8 Agonist 1 (hydrochloride) ≥98%	1620278-72-9	5mg	$515	2026-04-30	Buy
Biosynth	VPC27872	TLR7/8 agonist 1 dihydrochloride	1620278-72-9	25mg	$1260.75	2026-06-05	Buy
Biosynth	VPC27872	TLR7/8 agonist 1 dihydrochloride	1620278-72-9	50mg	$1754	2026-06-05	Buy

Product number	Packaging	Price	Buy
28451	500μg	$81	Buy
28451	1mg	$145	Buy
28451	5mg	$515	Buy
VPC27872	25mg	$1260.75	Buy
VPC27872	50mg	$1754	Buy

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Chemical Properties, Uses, Production

Biological Activity

TLR7/8 agonist 1 dihydrochloride is a dual agonist of the toll-like receptor TLR7/TLR8.

in vitro

TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity.It retains TLR7- agonistic activity with an EC ₅₀ of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.

target

TLR7/TLR8

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Suppliers

Global Suppliers ( 69)

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing Qishi Biotechnology Co. Ltd.	19822610310	3122922726@qq.com	China	147	58
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4859	55
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd	0431-80534353 19917294565	et@chemextension.com	China	3904	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
ShangHai Biochempartner Co.,Ltd	177-54423994 17754423994	2853530910@QQ.com	China	8000	62
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9729	58
Beijing Solarbio Science & Tecnology Co., Ltd.	17801761073 18101056239	3193328036@qq.com	China	28150	68
Zhengzhou Huiju Chemical Co., Ltd.	0371-55900031 18137872243	3927209986@qq.com	China	9999	55

Supplier	Advantage
Nanjing Qishi Biotechnology Co. Ltd.	58
Bide Pharmatech Ltd.	60
Shanghai Lollane Biological Technology Co.,Ltd.	55
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd	55
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
ShangHai Biochempartner Co.,Ltd	62
Shanghai Chaolan Chemical Technology Center	58
Beijing Solarbio Science & Tecnology Co., Ltd.	68
Zhengzhou Huiju Chemical Co., Ltd.	55

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride Spectrum

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride(1620278-72-9)¹HNMR

1620278-72-9 (1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride) Related Search:

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride 4-Amino-1-(3-amino-2,2-dimethylpropyl)-1H-imidazo[4,5-c]quinoline-2-ethanol BBIQ AXC-715 hydrochloride 1H-Imidazo[4,5-c]quinolin-4-amine, 1-[2-(2-aminoethoxy)ethyl]-2-(2-methoxyethyl)-

1H-Imidazo[4,5-c]quinolin-4-amine, 1-[[3-(aminomethyl)phenyl]methyl]-2-butyl-

1of2

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride TLR7/8 agonist 1 (dihydrochloride) TLR7/8 agonist-5d TLR7/8 Agonist 1 (hydrochloride) 8 agonist 1 dihydrochloride TLR7/8 Agonist 5d (hydrochloride) Toll-like Receptor (TLR),TLR7/8 agonist 1,TLR7/8 agonist 1 dihydrochloride,TLR-7/8 agonist 1 dihydrochloride,Inhibitor,inhibit TLR7/8 agonist 1 2HCl TLR7/8 agonist 1 dihydrochloride, 10 mM in DMSO 1620278-72-9