Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Acetamidophenol

2-Acetamidophenol

2-Acetamidophenol Structure
2-Acetamidophenol structure
CAS No.
614-80-2
Chemical Name:
2-Acetamidophenol
Synonyms
2-HYDROXYACETANILIDE;N-(2-Hydroxyphenyl)acetamide;2-ACETYLAMINOPHENOL;AcetaMinophen Related CoMpound C;NSC 398;NSC 3989;2-Acetamino;AKOS BBB/377;O AcetaMinophen;acetoaminophenol
CBNumber:
CB0342159
Molecular Formula:
C8H9NO2
Molecular Weight:
151.16
MDL Number:
MFCD00002181
MOL File:
614-80-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 17:39:28
Request For Quotation

2-Acetamidophenol Properties

Melting point 205-210 °C(lit.)
Boiling point 273.17°C (rough estimate)
Density 1.2023 (rough estimate)
refractive index 1.5810 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 9.35±0.35(Predicted)
form Powder
color Off-white to beige to brown
BRN 607592
Stability Stable. Incompatible with strong oxidizing agents, chloroformates, acids, acid chlorides, acid anhydrides.
InChI InChI=1S/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10)
InChIKey ADVGKWPZRIDURE-UHFFFAOYSA-N
SMILES C(NC1=CC=CC=C1O)(=O)C
CAS DataBase Reference 614-80-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 4AS8989RNI
NIST Chemistry Reference Acetamide, N-(2-hydroxyphenyl)-(614-80-2)
EPA Substance Registry System 2'-Hydroxyacetanilide (614-80-2)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/38-22-36/37/38
Safety Statements  26-36-37/39
RIDADR  2811
WGK Germany  3
RTECS  AE4025000
F  1-8
TSCA  TSCA listed
HazardClass  6.1(b)
PackingGroup  III
HS Code  29242995
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

2-Acetamidophenol price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A7000 2-Acetamidophenol 97% 614-80-2 25g $53.5 2026-04-30 Buy
Sigma-Aldrich A7000 2-Acetamidophenol 97% 614-80-2 100g $98.9 2026-04-30 Buy
Sigma-Aldrich 1003031 Acetaminophen Related Compound C United States Pharmacopeia (USP) Reference Standard 614-80-2 50mg $1340 2026-04-30 Buy
TCI Chemical H0189 2'-Hydroxyacetanilide >99.0%(HPLC)(N) 614-80-2 25g $112 2026-04-30 Buy
Cayman Chemical 35829 N-acetyl-2-Aminophenol ≥98% 614-80-2 25g $29 2026-04-30 Buy
Product number Packaging Price Buy
A7000 25g $53.5 Buy
A7000 100g $98.9 Buy
1003031 50mg $1340 Buy
H0189 25g $112 Buy
35829 25g $29 Buy

2-Acetamidophenol Chemical Properties, Uses, Production

Chemical Properties

white or light brown powder.soluble in hot water and ethanol, slightly soluble in cold water.

Uses

An Acetaminophen (A161220) impurity.
2-Acetamidophenol is used as raw material to manufacture industrial organic chemicals.
Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis.

Definition

ChEBI: 2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as a platelet aggregation inhibitor, an anti-inflammatory agent, a xenobiotic metabolite, an apoptosis inducer, an antineoplastic agent and an antirheumatic drug. It is a member of phenols and a member of acetamides.

Preparation

Mix 2-Aminophenol , acetic acid and Acetic anhydride (i.e., crystals appear), and then directly heated on the fire until all dissolved, stop heating, cooling, water dilution, precipitation of crystals filtered dry, to 70-80 ℃ of ethanol recrystallization to obtain 2-acetamidophenol.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Purification Methods

Recrystallise it from water, EtOH or Est aqueous EtOH. [Beilstein 13 H 370, 13 I 113, 13 II 171, 13 III 778.]

2-Acetamidophenol synthesis

108-24-7
95-55-6
614-80-2
Synthesis of 2-Acetamidophenol from Acetic anhydride and 2-Aminophenol

2-Acetamidophenol Preparation Products And Raw materials

Raw materials

2-Aminophenol Acetic anhydride

Preparation Products

4-Bromo-2-hydroxybenzoic acid 2-Methylbenzoxazole 6-Bromo-2H-1,4-benzoxazin-3(4H)-one N-(2-Butyloxyphenyl)acetamide Dimethyl 2-(4-methoxybenzyl)malonate

2-Acetamidophenol Suppliers

Global Suppliers ( 366)
Supplier Tel Email Country ProdList Advantage
Pushan Industry (Shaanxi) Co., Ltd. 029-81310890 18165209495 2929288192@qq.com China 9949 58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd. 0513-82104991 18862997351 sales11@btcpharm.com China 859 58
Nanjing Tianyi Chemical Technology Co., Ltd 15150528611 779881375@qq.com China 64 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Yangzhou Aoxin Chemical Co., Ltd 0514-87754778 13901446058 sales@aochem.com China 69 66
Supplier Advantage
Pushan Industry (Shaanxi) Co., Ltd. 58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd. 58
Nanjing Tianyi Chemical Technology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
3B Pharmachem (Wuhan) International Co.,Ltd. 69
future industrial shanghai co., ltd 65
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Yangzhou Aoxin Chemical Co., Ltd 66

View Latest Price from 2-Acetamidophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Acetamidophenol pictures 2026-05-11 2-Acetamidophenol
614-80-2
 $29.00 99.93% 10g TargetMol Chemicals Inc.
2-Acetamidophenol pictures 2026-03-20 2-Acetamidophenol
614-80-2
 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Acetamidophenol pictures 2025-06-27 2-Acetamidophenol
614-80-2
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd

2-Acetamidophenol Spectrum

2-Acetamidophenol(614-80-2)MS2-Acetamidophenol(614-80-2)1HNMR2-Acetamidophenol(614-80-2)IR12-Acetamidophenol(614-80-2)IR22-Acetamidophenol(614-80-2)Raman

614-80-2 (2-Acetamidophenol) Related Search:

4-Aminophenol p-Acetotoluidide 3-Diethylaminophenol 4-Hydroxyaniline hydrochloride Acetamide
4'-Nitroacetanilide 4'-Aminoacetanilide 2-Aminophenol 2-Benzoylacetanilide 3-Chloro-4-hydroxyacetanilide
2-Acetamidofluorene 4,4'-Iminodiphenol hydrochloride 4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one 4'-Hydroxyacetophenone 2'-Hydroxyacetophenone
4'-Chloroacetanilide Acetaminophen impurity B 4-Acetoxyacetanilide

1of4

2-ACETAMIDOPHENOL 2-ACETAMINO PHENOL Acetaminophen Related Compound C (50 mg) (N-(2-hydroxyphenyl)acetamide) AKOS BBB/377 O-HYDROXYACETANILIDE O-ACETAMIDOPHENOL O-ACETAMINOPHENOL 2'-HYDROXYACETANILIDE 2’-hydroxy-acetanilid 2-acetamido-pheno 2-Hydroxyanilid kyseliny octove 2-hydroxyanilidkyselinyoctove Acetanilide, 2'-hydroxy- Acet-o-aminofenol n-(2-hydroxyphenyl)-acetamid N-(2-hydroxyphenyl)ethanamide N-Acetyl-2-aminophenol N-Acetyl-o-aminophenol o-(Acetylamino)phenol o-Acetylaminofenol Phenol, 2-acetamido- Paracetamol EP Impurity A(2-Acetamidophenol) 2-Acetamidophenol99% 2-Acetamidophenol,97% 2-(N-Acetylamino)phenol NSC 398 2-Acetamino o-Acetamidophenol AP ORTHO-HYDROXYACETANILIDE 2-HYDROXYACETANILIDE / 2-ACETAMIDOPHENOL NSC 3989 o-Aminophenol N-acetate 2-Acetamide phenol O AcetaMinophen ParacetaMol IMpurity A 2-AcetaMidophenol, 98.5% Paracetamol EP Impurity A Paracetamol Impurity 1(Paracetamol EP Impurity A) 2'-Hydroxyacetanilide> N-(2-Hydroxyphenyl)acetamide (2-Ace Acetamide, N-(2-hydroxyphenyl)- acetoaminophenol Paracetamol(Acetaminophen) EP Impurity A Paracetamol EP Impurity Acetaminophen related compound C Paracetamol Impurity A Acetaminophen impurities1455 Acetaminophen EP Impurity A Acetaminophen Related Compound C (R00920) Acetaminophen Related Compound C (N-(2-hydroxyphenyl)acetamide) (1003031) Acetaminophen USP Related Compound C 2 Acetamidophenol,2Acetamidophenol 2'-Hydroxyacetanilide, ≥ 99.0% Acetaminophene Related Compound C PARACETAMOL EP IMP A/Acetaminophen USP RC C Paracetamol EP Impurity A N-(2-hydroxyphenyl)acetamide Paracetamol EP Impurity A (Acetaminophen USP Related Compound C) 2-Acetamidophenol, 10 mM in DMSO 2-ACETYLAMINOPHENOL