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4-Hydroxyaniline hydrochloride

CAS No.
51-78-5
Chemical Name:
4-Hydroxyaniline hydrochloride
Synonyms
4-AMINOPHENOL HYDROCHLORIDE;P-AMINOPHENOL HYDROCHLORIDE;furrop;ci76551;peltolp;FurBrownp;fourrinep;pelagolcp;c.i.76551;futraminep
CBNumber:
CB6853727
Molecular Formula:
C6H8ClNO
Molecular Weight:
145.59
MDL Number:
MFCD00012996
MOL File:
51-78-5.mol
MSDS File:
SDS
Last updated:2026-05-28 06:31:36

4-Hydroxyaniline hydrochloride Properties

Melting point 302 °C
Boiling point 306°C (decomp)
storage temp. Store below +30°C.
solubility DMSO (Slightly), Methanol (Slightly)
form powder
color gray
Water Solubility soluble
Merck 14,462
BRN 3911747
Stability Stable, but hygroscopic, air and light sensitive. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions HAIR DYEING
InChI 1S/C6H7NO.ClH/c7-5-1-3-6(8)4-2-5;/h1-4,8H,7H2;1H
InChIKey RVGOBWDGAVAVPJ-UHFFFAOYSA-N
SMILES Cl[H].Nc1ccc(O)cc1
CAS DataBase Reference 51-78-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII IWL2N22RFY
EPA Substance Registry System 4-Aminophenol hydrochloride (51-78-5)
UNSPSC Code 12352107
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H332-H315-H319-H317-H335
Precautionary statements  P501-P261-P272-P270-P271-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P333+P313-P301+P312+P330-P304+P340+P312-P403+P233-P405
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38-43
Safety Statements  28-36
WGK Germany  3
RTECS  SJ6070000
TSCA  TSCA listed
HS Code  29222900
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Acute 1
Carc. 2
Eye Dam. 1
Muta. 2
Skin Sens. 1
STOT RE 1
Hazardous Substances Data 51-78-5(Hazardous Substances Data)
Toxicity LD50 slt-dmg-orl: 750 mg/kg NTIS** AD691-490
NFPA 704
1
2 1

4-Hydroxyaniline hydrochloride price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.20092 4-Hydroxyanilinium chloride for synthesis 51-78-5 100G $316 2026-04-30 Buy
Sigma-Aldrich 09170 4-Aminophenol hydrochloride for photographic purposes, ≥99.0% (AT) 51-78-5 500g $346 2023-06-20 Buy
Sigma-Aldrich 09170 4-Aminophenol hydrochloride for photographic purposes, ≥99.0% (AT) 51-78-5 100g $103 2023-01-07 Buy
TCI Chemical A0392 4-Aminophenol Hydrochloride >98.0%(HPLC)(N) 51-78-5 25g $59 2026-04-30 Buy
TCI Chemical A0392 4-Aminophenol Hydrochloride >98.0%(HPLC)(N) 51-78-5 100g $182 2026-04-30 Buy
Product number Packaging Price Buy
8.20092 100G $316 Buy
09170 500g $346 Buy
09170 100g $103 Buy
A0392 25g $59 Buy
A0392 100g $182 Buy

4-Hydroxyaniline hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Off white powder

Uses

4-Aminophenol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using surface enhanced Raman scattering method.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. 4-Aminophenol hydrochloride can be used to study cell biology, bioactive small molecules, chemical synthesis, organic building blocks, oxygen compounds and phenols.

Safety Profile

Moderately toxic byintraperitoneal route. Mutation data reported. Whenheated to decomposition it emits very toxic fumes of HCland NOx.

Purification Methods

Purify the salt by treating an aqueous solution with saturated Na2S2O3, filtering under N2, then recrystallising it from 50% EtOH twice and once from absolute EtOH [Livingston & Ke J Am Chem Soc 72 909 1950]. [Beilstein 13 III 993.]

108-95-2
51-78-5
Synthesis of 4-Hydroxyaniline hydrochloride from Phenol

4-Hydroxyaniline hydrochloride Preparation Products And Raw materials

Global( 165)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuxi KaiLi Biotech Co.,Ltd 0510-80721533 13327925606 sales@klbiotech.com China 134 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Winchem Industrial Co. Ltd 0574-83851061 info@win-chemical.com China 500 55
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
China Langchem Inc. 0086-21-58956006 China 7798 57
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57

View Lastest Price from 4-Hydroxyaniline hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hydroxyaniline hydrochloride pictures 2023-07-19 4-Hydroxyaniline hydrochloride
51-78-5
$10.00 1KG 99% 100MT/Month Wuhan wingroup Pharmaceutical Co., Ltd
4-Hydroxyaniline hydrochloride pictures 2019-07-06 4-Hydroxyaniline hydrochloride
51-78-5
$1.00 1G 98% 100KG Career Henan Chemical Co
ci76551 durafurbrownr fouraminecp fourrine83 fourrinep FurBrownp furrop futraminep p-amino-phenohydrochloride 4-Hydroxyanilinium chloride for synthesis P-AMINOPHENOL HCL 4-AMINOPHENOL HCL 4-AMINOPHENOL HYDROCHLORIDE 4-HYDROXYANILINE HYDROCHLORIDE 4-HYDROXYANILINIUM CHLORIDE ρ-Aminophenol hydrochloride pelagolcp pelagolgreycp peltolp Phenol,4-amino-,hydrochloride p-hydroxyanilinehydrochloride 4-AMINOPHENOL HYDROCHLORIDE, FOR PHOTO-G RAPHIC PURPOSES AMINOPHENOL HYDROCHLORIDE , 4- PARA-AMINOPHENOLHYDROCHLORIDE 4-AMINOPHENOL HYDROCHLORIDE / 4-HYDROXYANILINE HCL C.I.Oxidation Base 6:1 4-Aminophenol hydrochloride,98% p-Aminophenol hydrochloride 4-Aminophenol hydrochloride 4-Hydroxyaniline hydrochloride Acetaminophen Impurity K HCl Paracetamol Impurity K HCl Paracetamol EP Impurity K Paracetamol Impurity 11(Paracetamol EP Impurity K) 4-amino-phenohydrochloride c.i.76551 C.I.OxidationBase6A(76551) 4-Aminophenol Hydrochloride > Acetaminophen Impurity K HCl (Paracetamol Impurity K HCl) 4-HYDROXYANILINIUM CHLORIDE FOR SYNTHESI P-AMINOPHENOL HYDROCHLORIDE (PAP-HCL) Paracetamol EP Impurity K HCl Acetaminophen EP Impurity K Acetaminophen Impurity K Hydrochloride (Paracetamol Impurity K Hydrochloride) Phenol, 4-amino-,hydrochloride (1:1) Mesalazine (Mesalamine) EP Impurity A HCl (Paracetamol EP Impurity K HCl) P-AMINOPHENOL HYDROCHLORIDE 51-78-5 H2NC6H4OHHCl C6H7ONHCl AMINE Oxygen Compounds Phenols Building Blocks Organic Building Blocks