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Indole-2-carboxylic acid

Indole-2-carboxylic acid structure

CAS No.: 1477-50-5

Chemical Name:: Indole-2-carboxylic acid

Synonyms: 1H-INDOLE-2-CARBOXYLIC ACID;2-INDOLECARBOXYLIC ACID;NSC 16598;e-2-carboxyL;AKOS JY2082713;2-CARBOXYINDOLE;Indol-2-carbonsure;Indole-2-carboxylic;2-Carboxy-1H-indole;TIMTEC-BB SBB003953

CBNumber:: CB7728231

Molecular Formula:: C9H7NO2

Molecular Weight:: 161.16

MDL Number:: MFCD00005611

MOL File:: 1477-50-5.mol

MSDS File:: SDS

Last updated:2026-01-13 11:24:39

Product description	Number	Pack Size	Price
Indole-2-carboxylic acid 98%	I5109	5g	$115
Indole-2-carboxylic acid 98%	I5109	10g	$116
Indole-2-carboxylic Acid >98.0%(GC)(T)	I0332	5g	$18
Indole-2-carboxylic Acid >98.0%(GC)(T)	I0332	25g	$37
Indole-2-carboxylic acid 98%	I5109	50g	$201
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Indole-2-carboxylic acid Properties

Melting point	202-206 °C(lit.)
Boiling point	287.44°C (rough estimate)
Density	1.2480 (rough estimate)
refractive index	1.5050 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in clear yellow solution 5% in ethanol, dimethyl sulfoxide and methanol.
pka	4.44±0.30(Predicted)
form	Crystalline Powder or Crystals
color	Off-white to yellow to brown
BRN	124132
InChI	InChI=1S/C9H7NO2/c11-9(12)8-5-6-3-1-2-4-7(6)10-8/h1-5,10H,(H,11,12)
InChIKey	HCUARRIEZVDMPT-UHFFFAOYSA-N
SMILES	N1C2=C(C=CC=C2)C=C1C(O)=O
CAS DataBase Reference	1477-50-5(CAS DataBase Reference)
EWG's Food Scores	1
NIST Chemistry Reference	Indole-2-carboxylic acid(1477-50-5)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Warning

Hazard statements

H301-H311-H315-H319-H335

Precautionary statements

P261-P280-P301+P310a-P305+P351+P338-P405-P501a

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Xn,Xi

Risk Statements

36/37/38-21/22

Safety Statements

22-24/25

WGK Germany

RTECS

NK7882812

HazardClass

IRRITANT

HS Code

29339990

Storage Class

11 - Combustible Solids

NFPA 704

	0
2		0

Indole-2-carboxylic acid price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	I5109	Indole-2-carboxylic acid 98%	1477-50-5	5g	$115	2025-07-31	Buy
Sigma-Aldrich	I5109	Indole-2-carboxylic acid 98%	1477-50-5	10g	$116	2025-07-31	Buy
TCI Chemical	I0332	Indole-2-carboxylic Acid >98.0%(GC)(T)	1477-50-5	5g	$18	2025-07-31	Buy
TCI Chemical	I0332	Indole-2-carboxylic Acid >98.0%(GC)(T)	1477-50-5	25g	$37	2025-07-31	Buy
Sigma-Aldrich	I5109	Indole-2-carboxylic acid 98%	1477-50-5	50g	$201	2025-07-31	Buy

Product number	Packaging	Price	Buy
I5109	5g	$115	Buy
I5109	10g	$116	Buy
I0332	5g	$18	Buy
I0332	25g	$37	Buy
I5109	50g	$201	Buy

Indole-2-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Powder

Uses

• ;Reactant for total synthesis of (±)-dibromophakellin and analogs1• ;Reactant for synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine2• ;Reactant for stereoselective preparation of renieramycin G analogs3• ;Reactant for preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization4• ;Reactant for Pd-catalyzed cyclization5• ;Reactant for preparation of N,N′-(pentane)diylbis[indolecarboxamide] and N,N′-[phenylenebis(

Uses

Reactant for total synthesis of (±)-dibromophakellin and analogs, synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine, stereo selective preparation of renieramycin G analogs, preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization, Pd-catalyzed cyclization and N,N-(pentane)diylbis[indolecarboxamide] and N,N-[phenylenebis(methylene)]bis[indolecarboxamide] derivatives.

Definition

ChEBI: Indole-2-carboxylic acid is an indolyl carboxylic acid.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 7961, 1992 DOI: 10.1016/S0040-4039(00)74789-7

IC 50

NMDA Receptor; Human Endogenous Metabolite

Indole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Indole-3-carboxylic acid ethyl 3-(o-nitrophenyl)pyruvate 2-BROMO-1H-INDOLE Ethyl indole-2-carboxylate

Preparation Products

3-Indolepropionic acid Indoline-2-carboxylic acid Methyl indole-2-carboxylate 3-FORMYL-1H-INDOLE-2-CARBOXYLIC ACID 1H-INDOL-2-YLMETHANOL

3-IODOINDOLE-2-CARBOXYLIC ACID 1H-Indole-2-methanol, α-methyl-

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Indole-2-carboxylic acid Suppliers

Global( 603)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8753	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5242	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20128	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21597	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +8618949832763	info@tnjchem.com	China	2988	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Fengda Chemical Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Hefei TNJ Chemical Industry Co.,Ltd.	55
career henan chemical co	58

View Lastest Price from Indole-2-carboxylic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-02-13	Indole-2-carboxylic acid 1477-50-5	US $0.00 / Kg/Drum	1KG	98%min	10 ton	WUHAN FORTUNA CHEMICAL CO., LTD
2026-01-30	Indole-2-carboxylic acid 1477-50-5	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-09-25	Indole-2-carboxylic acid 1477-50-5	US $122.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

Indole-2-carboxylic acid
1477-50-5
US $0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Indole-2-carboxylic acid
1477-50-5
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Indole-2-carboxylic acid
1477-50-5
US $122.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

Indole-2-carboxylic acid Spectrum

Indole-2-carboxylic acid(1477-50-5)MS Indole-2-carboxylic acid(1477-50-5)¹HNMR Indole-2-carboxylic acid(1477-50-5)¹³CNMR Indole-2-carboxylic acid(1477-50-5)IR1 Indole-2-carboxylic acid(1477-50-5)IR2 Indole-2-carboxylic acid(1477-50-5)Raman

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NSC 16598 Indole-2-carboxylic Indole-2-earboxylic acid ethylester INDOLE-2-CARBOXYLIC ACID(I2CA) Indole-2-carboxylic acid,99% Indole-2-carboxylic acid 　 Indole-2-carboxylic acid Indole-2-carboxylacid 1H-Indole-2-carboxylic acid 98% Indole-2-carboxylic acid in stock Factory Indole-2-carboxylic acid, 99% 10GR 1H-Indole-2-carboxylic 1H-2-Indolecarboxylic acid 2-Carboxy-1H-indole AKOS JY2082713 2-CARBOXYINDOLE 2-INDOLECARBOXYLIC ACID Indole-2-carboxylic acid 98% 1H-INDOLE-2-CARBOXYLIC ACID INDOLE-1H-2-CARBOXYLIC ACID INDOLE-2-CARBOXYLIC ACID OTAVA-BB BB7013890553 TIMTEC-BB SBB003953 indole-2-carboxlicacid Indole-2-carboxylate acid Indole-3-CarboxylicAcidForBiochemistry 2-IndolecarboxylicAcid:Indole-2-CarboxylicAcid Indole-2-carboxylic acid, 98+% 2-Indolylformic Acid e-2-carboxyL Indole-2-carboxylicAcid> Indol-2-carbonsure ndole-2-carboxylic acid 2-Indole-3-carboxylic acid Indole-2-carboxylic acid, 95% Indole-2-carboxylic acid 1H-Indole-2-carboxylic acid Indole-2-carboxylic acid - [K31174] 1477-50-5 91477-50-5 Building Blocks Indoles Simple Indoles Heterocyclic Building Blocks Simple Indoles Amino Acids & Derivatives Indole Derivatives Carboxylic Acids Pyrroles & Indoles Carboxylic Acids Pyrroles & Indoles Indole Organic acids Amino Acids 13C, 2H, 15N Indoles Indole/indoline/oxindole indole derivative Indole and Indoline Indoles and derivatives commercial