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Indole-2-carboxylic acid

CAS No.
1477-50-5
Chemical Name:
Indole-2-carboxylic acid
Synonyms
1H-INDOLE-2-CARBOXYLIC ACID;2-INDOLECARBOXYLIC ACID;2-CARBOXYINDOLE;Indole-2-carboxylic;NSC 16598;e-2-carboxyL;AKOS JY2082713;Indol-2-carbonsure;2-Carboxy-1H-indole;TIMTEC-BB SBB003953
CBNumber:
CB7728231
Molecular Formula:
C9H7NO2
Molecular Weight:
161.16
MDL Number:
MFCD00005611
MOL File:
1477-50-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:04:06
Product description Number Pack Size Price
Indole-2-carboxylic acid 98% I5109 5g $123
Indole-2-carboxylic acid 98% I5109 10g $124
Indole-2-carboxylic Acid >98.0%(GC)(T) I0332 5g $20
Indole-2-carboxylic Acid >98.0%(GC)(T) I0332 25g $37
Indole-2-carboxylic Acid I0797-78 25g $439
More product size

Indole-2-carboxylic acid Properties

Melting point 202-206 °C(lit.)
Boiling point 287.44°C (rough estimate)
Density 1.2480 (rough estimate)
refractive index 1.5050 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in clear yellow solution 5% in ethanol, dimethyl sulfoxide and methanol.
pka 4.44±0.30(Predicted)
form Crystalline Powder or Crystals
color Off-white to yellow to brown
BRN 124132
InChI InChI=1S/C9H7NO2/c11-9(12)8-5-6-3-1-2-4-7(6)10-8/h1-5,10H,(H,11,12)
InChIKey HCUARRIEZVDMPT-UHFFFAOYSA-N
SMILES N1C2=C(C=CC=C2)C=C1C(O)=O
CAS DataBase Reference 1477-50-5(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference Indole-2-carboxylic acid(1477-50-5)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Warning
Hazard statements  H301-H311-H315-H319-H335
Precautionary statements  P261-P280-P301+P310a-P305+P351+P338-P405-P501a
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-21/22
Safety Statements  22-24/25
WGK Germany  3
RTECS  NK7882812
HazardClass  IRRITANT
HS Code  29339990
Storage Class 11 - Combustible Solids
NFPA 704
0
2 0

Indole-2-carboxylic acid price More Price(100)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I5109 Indole-2-carboxylic acid 98% 1477-50-5 5g $123 2026-04-30 Buy
Sigma-Aldrich I5109 Indole-2-carboxylic acid 98% 1477-50-5 10g $124 2026-04-30 Buy
TCI Chemical I0332 Indole-2-carboxylic Acid >98.0%(GC)(T) 1477-50-5 5g $20 2026-04-30 Buy
TCI Chemical I0332 Indole-2-carboxylic Acid >98.0%(GC)(T) 1477-50-5 25g $37 2026-04-30 Buy
Usbiological I0797-78 Indole-2-carboxylic Acid 25g $439 2026-06-03 Buy
Product number Packaging Price Buy
I5109 5g $123 Buy
I5109 10g $124 Buy
I0332 5g $20 Buy
I0332 25g $37 Buy
I0797-78 25g $439 Buy

Indole-2-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Powder

Uses

• ;Reactant for total synthesis of (±)-dibromophakellin and analogs1• ;Reactant for synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine2• ;Reactant for stereoselective preparation of renieramycin G analogs3• ;Reactant for preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization4• ;Reactant for Pd-catalyzed cyclization5• ;Reactant for preparation of N,N′-(pentane)diylbis[indolecarboxamide] and N,N′-[phenylenebis(

Uses

Reactant for total synthesis of (±)-dibromophakellin and analogs, synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine, stereo selective preparation of renieramycin G analogs, preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization, Pd-catalyzed cyclization and N,N-(pentane)diylbis[indolecarboxamide] and N,N-[phenylenebis(methylene)]bis[indolecarboxamide] derivatives.

Definition

ChEBI: Indole-2-carboxylic acid is an indolyl carboxylic acid.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 7961, 1992 DOI: 10.1016/S0040-4039(00)74789-7

IC 50

NMDA Receptor; Human Endogenous Metabolite

Global( 615)Suppliers
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Hebei Chuanghai Biotechnology Co,.LTD
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View Lastest Price from Indole-2-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Indole-2-carboxylic acid pictures 2026-08-19 Indole-2-carboxylic acid
1477-50-5
1KG 98%min 10 ton WUHAN FORTUNA CHEMICAL CO., LTD
Indole-2-carboxylic acid pictures 2026-08-17 Indole-2-carboxylic acid
1477-50-5
$1.00-122.00 1KG 99% Henan Fengda Chemical Co., Ltd
Indole-2-carboxylic acid pictures 2026-05-28 Indole-2-carboxylic acid
1477-50-5
$2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
NSC 16598 Indole-2-earboxylic acid ethylester INDOLE-2-CARBOXYLIC ACID(I2CA) Indole-2-carboxylic acid,99% Indole-2-carboxylic acid   Indole-2-carboxylic acid Indole-2-carboxylacid 1H-Indole-2-carboxylic acid 98% Indole-2-carboxylic acid in stock Factory Indole-2-carboxylic acid, 99% 10GR 1H-Indole-2-carboxylic 1H-2-Indolecarboxylic acid 2-Carboxy-1H-indole AKOS JY2082713 Indole-2-carboxylic acid 98% INDOLE-1H-2-CARBOXYLIC ACID INDOLE-2-CARBOXYLIC ACID OTAVA-BB BB7013890553 TIMTEC-BB SBB003953 indole-2-carboxlicacid Indole-2-carboxylate acid Indole-3-CarboxylicAcidForBiochemistry 2-IndolecarboxylicAcid:Indole-2-CarboxylicAcid Indole-2-carboxylic acid, 98+% 2-Indolylformic Acid e-2-carboxyL Indole-2-carboxylicAcid> Indol-2-carbonsure ndole-2-carboxylic acid 2-Indole-3-carboxylic acid Indole-2-carboxylic acid, 95% Indole-2-carboxylic acid 1H-Indole-2-carboxylic acid Indole-2-carboxylic acid - [K31174] 1H-INDOLE-2-CARBOXYLIC ACID 2-CARBOXYINDOLE 2-INDOLECARBOXYLIC ACID Indole-2-carboxylic 1477-50-5 91477-50-5 Building Blocks Indoles Simple Indoles Heterocyclic Building Blocks Simple Indoles Amino Acids & Derivatives Indole Derivatives Carboxylic Acids Pyrroles & Indoles Carboxylic Acids Pyrroles & Indoles Indole Organic acids Amino Acids 13C, 2H, 15N Indoles Indole/indoline/oxindole indole derivative Indole and Indoline Indoles and derivatives commercial