4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide
![4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide Structure](CAS/20180528/GIF/1216626-17-3.gif)
- CAS No.
- 1216626-17-3
- Chemical Name:
- 4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide
- Synonyms
- D5-Amisulpride;[2H5]-Amisulpride;Guaiacol Impurity 28;Amisulpride Impurity 27;Amisulpride-D5 solution;4-amino-5-(ethanesulfonyl)-N-({1-[(1,1,2,2,2-2H?)ethyl]pyrrolidin-2-yl}methyl)-2-methoxybenzamide;4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide;Amisulpride Hydrochloride D5Q: What is Amisulpride Hydrochloride D5 Q: What is the CAS Number of Amisulpride Hydrochloride D5 Q: What is the storage condition of Amisulpride Hydrochloride D5 Q: What are the applications of Amisulpride Hydrochloride D5
- CBNumber:
- CB03677791
- Molecular Formula:
- C17H22D5N3O4S
- Molecular Weight:
- 374.50978889
- MDL Number:
- MOL File:
- 1216626-17-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide Properties
| storage temp. | Store at -20°C |
|---|---|
| solubility | Chloroform: slightly soluble,Methanol: slightly soluble |
| form | A solid |
| color | White to off-white |
| Stability | Hygroscopic |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P233-P280-P301+P310-P303+P361+P353-P304+P340+P311 | |||||||||
| target organs | Eyes,Central nervous system | |||||||||
| WGK Germany | WGK 2 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Flam. Liq. 2 STOT SE 1 |
|||||||||
| NFPA 704 |
|
4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 30075 | Amisulpride-d5 ≥99%deuteratedforms(d1-d5) | 1216626-17-3 | 1mg | $379 | 2026-04-30 | Buy |
| TRC | TRC-A633252-1MG | Amisulpride-d5 >95%(HPLC) | 1216626-17-3 | 1mg | $349 | 2026-06-03 | Buy |
| TRC | TRC-A633252-10MG | Amisulpride-d5 >95%(HPLC) | 1216626-17-3 | 10mg | $2638 | 2026-06-03 | Buy |
| ChemScene | CS-0202017 | Amisulpride-d5 98.27% | 1216626-17-3 | 1mg | $87 | 2026-06-04 | Buy |
| ChemScene | CS-0202017 | Amisulpride-d5 98.27% | 1216626-17-3 | 5mg | $217 | 2026-06-04 | Buy |
4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide Chemical Properties, Uses, Production
Description
Amisulpride-d5 is intended for use as an internal standard for the quantification of amisulpride by GC- or LC-MS. Amisulpride is a dopamine D2 and D3 receptor antagonist (Kis = 3 and 3.5 nM, respectively). It is also an antagonist of the serotonin (5-HT) receptor subtypes 5-HT2B, 5-HT7, and 5-HT7A (Kis = 13, 11.5, and 135.5 nM, respectively). It is selective for these receptors over a panel of 39 additional receptors, ion channels, and transporters (Kis = >1,000 nM for all). Amisulpride increases 7-OH-DPAT-induced decreases in dopamine and acetylcholine release in electrically stimulated rat striatal slices (EC50s = 2.2 and 1.2 nM, respectively). It increases the levels of dopamine and the dopamine metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) in rat striatum and nucleus accumbens when administered intraperitoneally at a dose of 10 mg/kg. Amisulpride decreases immobility time in the forced swim test in rats, as well as reduces stress-induced decreases in sucrose consumption in a rat model of depression induced by chronic mild stress.
Uses
Labelled Amisulpride (A633250). Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.
IC 50
D3 Receptor
References
[1] ATHEIR I ABBAS. Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo.[J]. Psychopharmacology, 2009: 119-128. DOI: 10.1007/s00213-009-1521-8
[2] H SCHOEMAKER. Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity.[J]. Journal of Pharmacology and Experimental Therapeutics, 1997, 280 1: 83-97.
[3] M PAPP J W. Antidepressant-like activity of amisulpride in two animal models of depression.[J]. Journal of Psychopharmacology, 2000, 14 1: 46-52. DOI: 10.1177/026988110001400106
4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide Preparation Products And Raw materials
Raw materials
Preparation Products
4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Ziyong Zhizhan Biotechnology Co., Ltd. | 17780686372 | 410194348@qq.com | China | 1656 | 58 |
| Artis Biotech Co. Ltd. | 18108108965 18108108965 | sales@artisbio.com | China | 2503 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Hubei Yangxin Medical Technology Co., Ltd. | 15374522761 | 3003392093@yongstandards.com | China | 9995 | 55 |
| Tianjin shijia biomedical technology co., LTD | 15022261580 | tjshj1212@163.com | China | 2749 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| ShangHai Anpel Co, Ltd. | 18502138905 | shanpel@anpel.com.cn | China | 9604 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Manhag Testing Technology Co., Ltd | 400-818 0104 18918165978 | yanyan.guo@bestown.net.cn | China | 7770 | 58 |
View Latest Price from 4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-11 | Amisulpride-D5
1216626-17-3
|
$197.00 | 10g | TargetMol Chemicals Inc. |
-
- Amisulpride-D5
1216626-17-3
- $197.00
- TargetMol Chemicals Inc.
