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Kaempferide

CAS No.
491-54-3
Chemical Name:
Kaempferide
Synonyms
KAEMPFERIDE;ARTEMISIA ANNUA;ARTEANNUIN;kaempferid;4'-METHOXY-3,5,7-TRIHYDROXYFLAVONE;ARTEANUIN;QINGHAOSA;Kaemperide;ARTEMISINE;Kempferide
CBNumber:
CB0387974
Molecular Formula:
C16H12O6
Molecular Weight:
300.26
MDL Number:
MFCD00016771
MOL File:
491-54-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
Kaempferide analytical standard 69545 10mg $594
Kaempferide >96.0%(GC) K0057 10mg $120
Kaempferide >96.0%(GC) K0057 50mg $347
Kaempferide ≥95% 29673 5mg $75
Kaempferide ≥95% 29673 10mg $134
More product size

Kaempferide Properties

Melting point 156-157 °C(lit.)
Boiling point 543.8±50.0 °C(Predicted)
Density 1.538
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Chloroform (Slightly, Heated), DMSO (Slightly, Heated), Methanol (Slightly, Heat
pka 6.32±0.40(Predicted)
form Solid
color Yellow
BRN 305378
Major Application food and beverages
InChI InChI=1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3
InChIKey SQFSKOYWJBQGKQ-UHFFFAOYSA-N
SMILES C1(C2=CC=C(OC)C=C2)OC2=CC(O)=CC(O)=C2C(=O)C=1O
LogP 2.740 (est)
CAS DataBase Reference 491-54-3
FDA UNII 508XL61MPD
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
WGK Germany  2
RTECS  KD4170000
HS Code  29329990
Storage Class 11 - Combustible Solids

Kaempferide price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 69545 Kaempferide analytical standard 491-54-3 10mg $594 2026-04-30 Buy
TCI Chemical K0057 Kaempferide >96.0%(GC) 491-54-3 10mg $120 2026-04-30 Buy
TCI Chemical K0057 Kaempferide >96.0%(GC) 491-54-3 50mg $347 2026-04-30 Buy
Cayman Chemical 29673 Kaempferide ≥95% 491-54-3 5mg $75 2026-04-30 Buy
Cayman Chemical 29673 Kaempferide ≥95% 491-54-3 10mg $134 2026-04-30 Buy
Product number Packaging Price Buy
69545 10mg $594 Buy
K0057 10mg $120 Buy
K0057 50mg $347 Buy
29673 5mg $75 Buy
29673 10mg $134 Buy

Kaempferide Chemical Properties,Uses,Production

Chemical Properties

Yellow powder

Uses

Kaempferide is a flavonoid that maintains anti-radical and anti-oxidant capabilities, as well as anti-tumour possibilities. Impurity of Icaritin (I163700).

Definition

ChEBI: A monomethoxyflavone that is the 4'-O-methyl derivative of kaempferol.

Biological Activity

the effects of phytoestrogens have been studied in the hypothalamic-pituitary-gonadal axis and various non-gonadal targets. epidemiologic and experimental evidence indicates a protective effect of phytoestrogens also in colorectal cancer. the mechanism through which estrogenic molecules control colorectal cancer tumorigenesis could possibly involve estrogen receptor β, which is the predominantly expressed estrogen receptor subtype in colon mucosa.

in vitro

kaempferide triglycoside proved to inhibit the proliferation of native and estrogen receptor β overexpressing colon cancer cells via a mechanism not mediated by ligand binding dependent estrogen receptor activation. it affected hct8 cell cycle progression through increasing the g0/g1 cell fraction and in estrogen receptor β overexpressing cells increased two antioxidant enzymes [1].

in vivo

the aim of one previous study was to evaluate the effect of kaempferol on tissue lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal cancer in male wistar rats and to compare its efficacy with irinotecan. this study revealed that kaempferol could be safely used as a chemopreventive agent in colorectal cancer [2].

References

[1] martineti v, tognarini i, azzari c, carbonell sala s, clematis f, dolci m, lanzotti v, tonelli f, brandi ml, curir p. inhibition of in vitro growth and arrest in the g0/g1 phase of hct8 line human colon cancer cells by kaempferide triglycoside from dianthus caryophyllus. phytother res. 2010 sep;24(9):1302-8.
[2] nirmala p, ramanathan m. effect of kaempferol on lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal carcinoma in rats. eur j pharmacol. 2011 mar 1;654(1):75-9.

Kaempferide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 294)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21531 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3618 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29766 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +86-18080483897 sales@biopurify.com China 4616 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 52513593@qq.com CHINA 2971 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1922 58
CONIER CHEM AND PHARMA LIMITED
sales@conier.com China 49906 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2934 58
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58

View Lastest Price from Kaempferide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
kaempferide pictures 2026-07-27 kaempferide
491-54-3
$179.00 99.64% 10g TargetMol Chemicals Inc.
Kaempferide pictures 2023-02-24 Kaempferide
491-54-3
5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
ARTEMISININ pictures 2019-07-06 ARTEMISININ
491-54-3
$302.00 1KG 99% 1000kg Career Henan Chemical Co
  • kaempferide pictures
  • kaempferide
    491-54-3
  • $179.00
  • 99.64%
  • TargetMol Chemicals Inc.
  • Kaempferide pictures
  • Kaempferide
    491-54-3
  • $0.00
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.

Kaempferide Spectrum

4’-methylkaempferol 3,5,7-trihydroxy-2-(4-methoxyphenyl)-1-benzopyran-4-one Kaempferide~3,5,7-Trihydroxy-4-methoxyflavone 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4-benzopyrone Kaemperide 3,5,7-Trihydroxy-2-(4-methoxy-phenyl)-chromen-4- KAEMPFERIDE ARTEMISIA P E ARTEMISINE ARTEMISININE ARTEANUIN ARTEANNUIN KAEMPFERIDE hplc 4''-METHOXY-3,5,7-TRIHYDROXYFLAVONE 97% KAEMPFERIDE WITH HPLC 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one Kempferide [DISCONTINUED] Replaced by KIT-00010955-005 4’-o-methylkaempferol SWEET WORMWOOD QINGHAOSA ALPHA BETA ARTEMISININ 3,5,7-TRIHYDROXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE KaeMpferol 4'-O-Methyl ether KaeMpferide, froM KaeMpferia galanga 5,7-Dihydroxy-4'-Methoxyflavonol CaMpheride KaMpheride 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4h-1-benzopyran-4-on 4’-methoxy-3,5,7-trihydroxy-flavanon Kaempferide, 99%, from Kaempferia galanga 4'-MethoxykaeMpferol Flavone,3,5,7-trihydroxy-4'-Methoxy-(7CI,8CI) KaeMpferide(6CI) KaeMpferol4 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-methoxyphenyl)- ARTEMISININ 491-54-3 Icaritin Impurity 1 Kaempferol 4'-O-methyl ether|||Kaempferol 4'-methyl ether|||4'-Methylkaempferol|||4'-O-Methylkaempferol 3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-deoxy-alpha-L-mannopyranoside Kaempferide-RM kaempferide, 10 mM in DMSO kaempferide (Standard) 4'-METHOXY-3,5,7-TRIHYDROXYFLAVONE ARTEMISIA ANNUA kaempferid 491-54-3 Flavanols chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract