ChemicalBook >> CAS DataBase List >>KAEMPFEROL-3-O-RUTINOSIDE

KAEMPFEROL-3-O-RUTINOSIDE

KAEMPFEROL-3-O-RUTINOSIDE structure

CAS No.: 17650-84-9

Chemical Name:: KAEMPFEROL-3-O-RUTINOSIDE

Synonyms: NICOTIFLORIN;Nictoflorin;KAEMPFEROL-3-RUTINOSIDE;Nicotiflorine;Aempferol-3-O-rutinoside;Nicotifiorin;Nictoflorin (incorr;Kaempferol-3-O-rutinosid;Kaempferol-3-O-beta-rutinoside;Rutoside Trihydrate EP Impurity B

CBNumber:: CB6690629

Molecular Formula:: C27H30O15

Molecular Weight:: 594.52

MDL Number:: MFCD03427292

MOL File:: 17650-84-9.mol

MSDS File:: SDS

Last updated:2025-08-20 16:56:22

Product description	Number	Pack Size	Price
Kaempferol 3-O-β -rutinoside ≥98.0% (HPLC)	90242	1mg	$161
Kaempferol 3-rutinoside phyproof? Reference Substance	PHL80700	10MG	$489
Kaempferol 3-O-β -rutinoside ≥98.0% (HPLC)	90242	5mg	$292
Nicotiflorin	27392	1mg	$62
Nicotiflorin	27392	25mg	$893
More product size

Request For Quotation

KAEMPFEROL-3-O-RUTINOSIDE Properties

Melting point	200°C (dec.)
Boiling point	941.7±65.0 °C(Predicted)
Density	1.76
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	6.20±0.40(Predicted)
color	Off-White to Yellow
biological source	plant (Clematis cultivar)
Stability	Hygroscopic
InChIKey	RTATXGUCZHCSNG-FVJKAJKWNA-N
SMILES	C1(O[C@H]2[C@H](O)[C@H]([C@H](O)[C@@H](CO[C@@H]3O[C@H]([C@H](O)[C@@H](O)[C@H]3O)C)O2)O)C(=O)C2=C(C=C(O)C=C2O)OC=1C1C=CC(O)=CC=1 \|&1:2,3,5,6,8,11,13,14,16,18,r\|
FDA UNII	4056D20K3H
UNSPSC Code	41116107
NACRES	NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P280-P305+P351+P338

Hazard Codes

Risk Statements

Safety Statements

22-45-24/25

WGK Germany

HS Code

29389090

NFPA 704

	0
2		0

KAEMPFEROL-3-O-RUTINOSIDE price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	90242	Kaempferol 3-O-β -rutinoside ≥98.0% (HPLC)	17650-84-9	1mg	$161	2025-07-31	Buy
Sigma-Aldrich	PHL80700	Kaempferol 3-rutinoside phyproof? Reference Substance	17650-84-9	10MG	$489	2025-07-31	Buy
Sigma-Aldrich	90242	Kaempferol 3-O-β -rutinoside ≥98.0% (HPLC)	17650-84-9	5mg	$292	2025-07-31	Buy
Cayman Chemical	27392	Nicotiflorin	17650-84-9	1mg	$62	2024-03-01	Buy
Cayman Chemical	27392	Nicotiflorin	17650-84-9	25mg	$893	2024-03-01	Buy

Product number	Packaging	Price	Buy
90242	1mg	$161	Buy
PHL80700	10MG	$489	Buy
90242	5mg	$292	Buy
27392	1mg	$62	Buy
27392	25mg	$893	Buy

KAEMPFEROL-3-O-RUTINOSIDE Chemical Properties,Uses,Production

Description

Nicotiflorin is a flavonoid that has been found in I. glandulifera and has antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS radicals with EC₅₀ values of 0.52 and 0.48 mg/ml, respectively, in cell-free assays. Nicotiflorin (1 μM) prevents hydrogen peroxide-induced decreases in tyrosine hydroxylase activity in PC12 cells and cell death in primary rat mesencephalic neurons. It decreases infarct volume by 24.5, 45.8, and 63.2% when administered at doses of 2.5, 5, and 10 mg/kg, respectively, in a rat model of cerebral ischemia-reperfusion injury induced by transient middle central artery occlusion (MCAO).

Uses

Kaempferol 3-O-β -Rutinoside is a flavonoid antioxidant compound from Cichorium spinosum L. ecotype plants and also may display anti-diabetic activity. It is a component of many plant species including Helianthemum ruficomum.

Definition

ChEBI: Kaempferol-3-rutinoside is a kaempferol O-glucoside that is kaempferol attached to a rutinosyl [6-deoxy-alpha-L-mannosyl-(1->6)-beta-D-glucosyl] residue at position 3 via a glycosidic linkage. It has been isolated from the leaves of Solanum campaniforme. It has a role as a metabolite, a radical scavenger and a plant metabolite. It is a rutinoside, a trihydroxyflavone, a disaccharide derivative and a kaempferol O-glucoside.

General Description

Kaempferol 3-O-β -rutinoside is a bitter tasting flavonol glycoside that was isolated from flowers of a Clematis cultivar.

in vivo

At doses of 2.5, 5 and 10 mg/kg, nicotiflorin administered immediately after the onset of ischemia markedly reduces brain infarct volume and neurological deficits^[2]. Nicotiflorin (2.5-10 mg/kg) administered after onset of ischemia markedly reduces brain infarct volume by 24.5-63.2% and neurological deficits^[3].

References

[1] KATARZYNA SZEWCZYK . Phenolic constituents of the aerial parts of Impatiens glandulifera Royle (Balsaminaceae) and their antioxidant activities[J]. Natural Product Research, 2019, 33 19: Pages 2851-2855. DOI: 10.1080/14786419.2018.1499644
[2] WEI QU . Kaempferol Derivatives Prevent Oxidative Stress–Induced Cell Death in a DJ-1–Dependent Manner[J]. Journal of pharmacological sciences, 2009, 110 2: Pages 191-200. DOI: 10.1254/jphs.09045fp
[3] RUNPING LI . Nicotiflorin reduces cerebral ischemic damage and upregulates endothelial nitric oxide synthase in primarily cultured rat cerebral blood vessel endothelial cells[J]. Journal of ethnopharmacology, 2006, 107 1: Pages 143-150. DOI: 10.1016/j.jep.2006.04.024

KAEMPFEROL-3-O-RUTINOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

KAEMPFEROL-3-O-RUTINOSIDE Suppliers

Global( 272)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
Chengdu Greenpure Biopharma CO.,Ltd	18283602253; +8618283602253	jancyzheng@gcgreenpure.com	China	954	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	3751	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29799	58

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
Chengdu Greenpure Biopharma CO.,Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Standardpharm Co. Ltd.	58
BOC Sciences	58
Shanghai Standard Technology Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58

View Lastest Price from KAEMPFEROL-3-O-RUTINOSIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-02-24	Kaempferol-3-O-rutinoside 17650-84-9	US $0.00 / mg	5mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.
	2019-12-23	KAEMPFEROL-3-O-RUTINOSIDE 17650-84-9	US $1.00 / g	100g	99%	G/kg/t	Career Henan Chemical Co

Kaempferol-3-O-rutinoside
17650-84-9
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

KAEMPFEROL-3-O-RUTINOSIDE
17650-84-9
US $1.00 / g
99%
Career Henan Chemical Co

KAEMPFEROL-3-O-RUTINOSIDE Spectrum

KAEMPFEROL-3-O-RUTINOSIDE(17650-84-9)¹HNMR

17650-84-9(KAEMPFEROL-3-O-RUTINOSIDE)Related Search:

ARTEMISININ Sanggenon C kaempferol 3-O-sophoroside KaeMpferol-4'-O-β-D-glucopyranoside Kaempferol

KAEMPFERITRIN KAEMPFEROL-7-O-GLUCOSIDE Kaempferol 3-neohesperidoside Kaempferol 3-(6-O-glucopyranosylglucoside) Kaempferol 3-sophoroside-7-glucoside

KaeMpferol 3-sophoroside-7-rhaMnoside KAEMPFEROL 3-A-L-ARABINOPYRANOSIDE 7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-3,5-dihydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one kaempferol-3-O-galactoside KaeMpferol 7-O-rhaMnoside

KAEMPFEROL-3-GLUCURONIDE Kaempferol-3-O-(2,6-di-O-trans-p-coumaroyl)-beta-D-glucopyranoside kaempferol-3-O-glucosyl(1-2)rhamnoside

1of4

KaeMpferol-3-O-rutinoside, Nicotiflorin Nictoflorin (incorr 4H-1-Benzopyran-4-one,3-[[6-O-(6-deoxy-a-L-Mannopyranosyl)-b-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)- 3,4′,5,7-Tetrahydroxyflavone 3-rhamnoglucoside KaeMpferol-3-O-rutinosid, froM CarthaMus tinctorius Kaempferol-3-O-rutinosid Aempferol-3-O-rutinoside NICOTIFLORIN KAEMPFEROL-3-O-RUTINOSIDE KAEMPFEROL-3-RUTINOSIDE Kaempfeol-3-O-rutinoside KAEMPFEROL-3-O-RUTINOSIDE WITH HPLC KAEMPFEROL-3-RUTINOSIDE hplc 3-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(4-hydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one 3-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Kaempferol 3-rhamnoglucoside Nicotoflorin Kaempferol-3-O-rutinosid ,98% 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Nicotifiorin Nicotiflorine Nicotifloroside Kaempferol-3-O-rutinosid, 98%, from Carthamus tinctorius L. Kaempferol-3-O-rutinosid, ≥98.0%(HPLC) Rutoside Trihydrate Impurity 2（Rutoside Trihydrate EP Impurity B） Rutoside Trihydrate EP Impurity B Nicotiflorin (Kaempferol-3-O-beta-Rutinoside) Nictoflorin Kaempferol-3-O-beta-rutinoside Rutoside EP Impurity B 4H-1-Benzopyran-4-one, 3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)- Kaempferol 3-O-β -Rutinoside (Nicotiflorin) Kaempferol 3-O-beta -Rutinoside (Nicotiflorin) Kaempferol 3-O-β -rutinoside 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one 5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one Kaempferol 3-rutinoside-RM Rutoside Trihydrate EP Impurity B (Kaempferol-3-O-Beta-Rutinoside) Kaempferol 3-O-b -Rutinoside (Nicotiflorin) Kaempferol 3-O-β -rutinoside Nicotiflorin (Kaempferol-3-O-rutinoside) 17650-84-9 Tetra-substituted Flavones chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract