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3-Chloro-2-iodophenol

CAS No.
858854-82-7
Chemical Name:
3-Chloro-2-iodophenol
Synonyms
3-Choro-2-iodophenol;3-Chloro-2-iodophenol;Phenol, 3-chloro-2-iodo-
CBNumber:
CB0390983
Molecular Formula:
C6H4ClIO
Molecular Weight:
254.45
MDL Number:
MFCD08166414
MOL File:
858854-82-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:48:19

3-Chloro-2-iodophenol Properties

Melting point 56 °C
Boiling point 225.6±20.0 °C(Predicted)
Density 2.087±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 7.55±0.10(Predicted)
Appearance Off-white to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

3-Chloro-2-iodophenol price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS118493 3-Chloro-2-iodophenol 97% 858854-82-7 1g $125 2026-06-04 Buy
Activate Scientific AS118493 3-Chloro-2-iodophenol 97% 858854-82-7 5g $465 2026-06-04 Buy
Matrix Scientific 209260 3-Chloro-2-iodophenol 858854-82-7 250.00mg $41 2026-05-18 Buy
Matrix Scientific 209260 3-Chloro-2-iodophenol 858854-82-7 1.00g $68 2026-05-18 Buy
Matrix Scientific 209260 3-Chloro-2-iodophenol 858854-82-7 5.00g $332 2026-05-18 Buy
Product number Packaging Price Buy
AS118493 1g $125 Buy
AS118493 5g $465 Buy
209260 250.00mg $41 Buy
209260 1.00g $68 Buy
209260 5.00g $332 Buy

3-Chloro-2-iodophenol Chemical Properties, Uses, Production

Synthesis

3-CHLORO-2-IODOPHENYL N,N-DIETHYLCARBAMATE

863870-77-3

3-CHLORO-2-IODOPHENOL

858854-82-7

Step 3: Sodium hydroxide (32.0 g, 800 mmol) was slowly added to a 400 mL ethanol solution containing 3-chloro-2-iodophenyl N,N-diethylcarbamate (57.0 g, 161 mmol) at 25 °C. The reaction mixture was heated to reflux and maintained for 2 hours. Upon completion of the reaction, the ethanol solvent was removed by distillation under reduced pressure. The residue was dissolved in 400 mL of water and subsequently extracted with petroleum ether. The aqueous phase was neutralized with 2N hydrochloric acid solution and extracted with ethyl acetate. All organic phases were combined, washed with saturated brine and dried over anhydrous sodium sulfate. Finally, the organic solvent was removed by distillation under reduced pressure to afford the target product 3-chloro-2-iodophenol (41.0 g, quantitative yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 5.58 (brs, 1H), 6.90 (dd, J = 1.2,8.4 Hz, 1H), 7.06 (dd, J = 1.2,8.0 Hz, 1H), 7.21 (t, J = 8.0 Hz, 1H).

References

[1] Patent: US2017/145005, 2017, A1. Location in patent: Paragraph 0368; 0375; 0376; 0377
[2] Journal of Organic Chemistry, 2005, vol. 70, # 16, p. 6548 - 6551
[3] Journal of Organic Chemistry, 2007, vol. 72, # 14, p. 5113 - 5118
[4] Organic and Biomolecular Chemistry, 2010, vol. 8, # 17, p. 3860 - 3864
[5] Journal of Organic Chemistry, 2011, vol. 76, # 9, p. 3416 - 3437

863870-77-3
858854-82-7
Synthesis of 3-Chloro-2-iodophenol from 3-Chloro-2-iodophenyl N,N-diethylcarbamate
Global Suppliers ( 59)
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Jalor-Chem co.,LTD 0510-0510-86396359 13382276200 sales@jalor-chem.com China 1000 56
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
Tianjin Anhao Biological Technology Co., Ltd. sales@ahpharmatech.com China 5734 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
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Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
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Capot Chemical Co.,Ltd. +86-(0)57185586718 +86-13336195806 sales@capot.com China 29626 60

View Latest Price from 3-Chloro-2-iodophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-CHLORO-2-IODOPHENOL pictures 2020-01-09 3-CHLORO-2-IODOPHENOL
858854-82-7
$2.00 1g 98%min Career Henan Chemical Co

3-Chloro-2-iodophenol Spectrum

3-Choro-2-iodophenol Phenol, 3-chloro-2-iodo- 3-Chloro-2-iodophenol 858854-82-7 pharmacetical