ChemicalBook >> CAS DataBase List >>2,2-Dimethyl-N-pyridin-4-yl-propionamide

2,2-Dimethyl-N-pyridin-4-yl-propionamide

2,2-Dimethyl-N-pyridin-4-yl-propionamide structure

CAS No.: 70298-89-4

Chemical Name:: 2,2-Dimethyl-N-pyridin-4-yl-propionamide

Synonyms: N-(4-Pyridyl)pivalamide;4-(pivaloylamino)pyridine;N-(4-Pyridyl)pivalamide>N-(Pyridin-4-yl)pivalamide;2,2-Dimethyl-N-(4-pyridinyl)propanamid;2,2-Dimethyl-N-(4-pyridyl)propionamide;2,2-Dimethyl-N-pyridin-4-ylpropanamide;2,2-DIMETHYL-N-(4-PYRIDINYL)PROPANAMIDE;Propanamide, 2,2-dimethyl-N-4-pyridinyl-;2,2-Dimethyl-N-pyridin-4-yl-propionamide

CBNumber:: CB0404822

Molecular Formula:: C10H14N2O

Molecular Weight:: 178.23

MDL Number:: MFCD00996248

MOL File:: 70298-89-4.mol

MSDS File:: SDS

Last updated:2026-09-12 18:48:19

Request For Quotation

2,2-Dimethyl-N-pyridin-4-yl-propionamide Properties

Melting point	73.9-74.0°C
storage temp.	Inert atmosphere,Room Temperature
solubility	soluble in Methanol
form	powder to crystal
color	White to Almost white
InChI	InChI=1S/C10H14N2O/c1-10(2,3)9(13)12-8-4-6-11-7-5-8/h4-7H,1-3H3,(H,11,12,13)
InChIKey	JCMMVFHXRDNILC-UHFFFAOYSA-N
SMILES	C(NC1C=CN=CC=1)(=O)C(C)(C)C
CAS DataBase Reference	70298-89-4

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c

Hazard Codes

Xi,Xn

Risk Statements

HazardClass

IRRITANT

HS Code

29333990

NFPA 704

	1
2		0

2,2-Dimethyl-N-pyridin-4-yl-propionamide price More Price(67)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	MNO000019	2,2-Dimethyl-N-pyridin-4-yl-propionamide Aldrich	70298-89-4	1g	$68.1	2023-01-07	Buy
TCI Chemical	P2044	N-(4-Pyridyl)pivalamide >98.0%(GC)	70298-89-4	1g	$94	2024-03-01	Buy
TCI Chemical	P2044	N-(4-Pyridyl)pivalamide >98.0%(GC)	70298-89-4	5g	$277	2024-03-01	Buy
AstaTech	AR2618	N-(PYRIDIN-4-YL)PIVALAMIDE 95%	70298-89-4	5G	$39	2026-04-30	Buy
Biosynth	VCA29889	2,2-Dimethyl-N-pyridin-4-yl-propionamide	70298-89-4	10g	$354	2026-06-05	Buy

Product number	Packaging	Price	Buy
MNO000019	1g	$68.1	Buy
P2044	1g	$94	Buy
P2044	5g	$277	Buy
AR2618	5G	$39	Buy
VCA29889	10g	$354	Buy

2,2-Dimethyl-N-pyridin-4-yl-propionamide Chemical Properties, Uses, Production

Chemical Properties

Light yellow solid

Definition

ChEBI: 2,2-Dimethyl-N-(4-pyridinyl)propanamide is a dihydropyridine.

Synthesis

504-24-5

3282-30-2

70298-89-4

a) General procedure for the synthesis of 2,2-dimethyl-N-(pyridin-4-yl)propionamide: 4-Aminopyridine (2 g, 21.3 mmol) was dissolved in dichloromethane (20 ml), to which pentanoyl chloride (3.1 ml, 25.6 mmol) and triethylamine (8.9 ml, 63.9 mmol) were added sequentially dropwise at room temperature. The reaction mixture was stirred at room temperature for 15 h. The reaction was subsequently quenched by addition of water. The organic layer was extracted with ethyl acetate and the combined organic layers were washed with saturated sodium chloride solution (50 ml), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with dichloromethane:methanol (20:1, v/v) as eluent. The fraction containing the target product was collected and concentrated to afford N-(pyridin-4-yl)trimethylacetamide as a white solid (3.6 g, 95% yield).1H-NMR (CDCl3, 300 MHz) data were as follows: δ= 8.47 (d, J = 6.1 Hz, 2H), 7.79 (br s, 1H), 7.52 (d, J = 6.0 Hz, 2H), 7.52 (d, J = 6.0 Hz, 2H). 1.32 (s, 9H).

References

[1] Synthesis, 2009, # 13, p. 2267 - 2277
[2] Patent: US2011/28467, 2011, A1. Location in patent: Page/Page column 16
[3] Chemistry - A European Journal, 2013, vol. 19, # 20, p. 6435 - 6442
[4] Molecules, 2003, vol. 8, # 9, p. 678 - 686
[5] European Journal of Medicinal Chemistry, 2005, vol. 40, # 1, p. 15 - 23

2,2-Dimethyl-N-pyridin-4-yl-propionamide synthesis

Synthesis of 2,2-Dimethyl-N-pyridin-4-yl-propionamide from 4-Amino-3-bromopyridine

2,2-Dimethyl-N-pyridin-4-yl-propionamide Preparation Products And Raw materials

Raw materials

Hexane Sodium sulfate Triethylamine Pivaloyl chloride Sodium bicarbonate

Dichloromethane Methylcyclohexane Magnesium sulfate 4-Aminopyridine 4-Amino-3-bromopyridine

Pivalic acid

1of3

Preparation Products

thiazolo[5,4-c]pyridine 4-Pivalamidopyridine-3-boronic acid N-(3-Formyl-4-pyridinyl)-2,2-dimethylpropanamide

2,2-Dimethyl-N-pyridin-4-yl-propionamide Suppliers

Global Suppliers ( 138)

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan BoYou Biotechnology Co., Ltd.	028-65791793 18140026355	568470422@qq.com	China	9961	58
Shanghai Brain Biotechnology Co., Ltd.	13564638271	shhjiang1977@163.com	China	2985	55
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Suzhou Banya Chem-Sci&Tech. Co., Ltd.	+86 (512) 6807-7352, +86 18915521230	market@banyachem.com	China	11	62

Supplier	Advantage
Sichuan BoYou Biotechnology Co., Ltd.	58
Shanghai Brain Biotechnology Co., Ltd.	55
J & K SCIENTIFIC LTD.	76
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Wuhan Chemwish Technology Co., Ltd	56
Beijing Ouhe Technology Co., Ltd	60
Jia Xing Isenchem Co.,Ltd	66
Adamas Reagent, Ltd.	59
Suzhou Banya Chem-Sci&Tech. Co., Ltd.	62

View Latest Price from 2,2-Dimethyl-N-pyridin-4-yl-propionamide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-20	2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE 70298-89-4	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2019-12-26	2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE 70298-89-4	$1.00	1KG	99%	200kg	Career Henan Chemical Co

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE
70298-89-4
$1.10
99.00%
Dideu Industries Group Limited

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE
70298-89-4
$1.00
99%
Career Henan Chemical Co

2,2-Dimethyl-N-pyridin-4-yl-propionamide Spectrum

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE(70298-89-4)¹HNMR

70298-89-4 (2,2-Dimethyl-N-pyridin-4-yl-propionamide) Related Search:

N-(3-Formyl-4-pyridinyl)-2,2-dimethylpropanamide Propionamide 4-(2,2-Dimethyl-propionylamino)-nicotinic acid methyl ester 2,2-Dimethyl-N-pyridin-4-yl-propionamide N-(3-Iodo-pyridin-4-yl)-2,2-dimethyl-propionamide

N-(3-Hydroxy-pyridin-4-yl)-2,2-dimethyl-propionamide 2,2-Dimethyl-N-pyridin-2-yl-propionamide 4-[(2,2-Dimethylpropanoyl)amino]nicotinic acid (Phenylcyclopentyl)-N-(4-pyridyl)formamide N-(3-tert-Butylsulfanyl-pyridin-4-yl)-2,2-dimethyl-propionamide

2,2-Dimethyl-N-pyridin-3-yl-propionamide N-(3-Dimethoxymethyl-pyridin-4-yl)-2,2-dimethyl-propionamide N-(3-[1,3]Dioxolan-2-yl-pyridin-4-yl)-2,2-dimethyl-propionamide 2,2-Dimethyl-N-(3-trimethylsilanyl-pyridin-4-yl)-propionamide 3-[4-(2,2-Dimethyl-propionylamino)-pyridin-3-yl]-acrylic acid ethyl ester

RARECHEM AL BL 1273 RARECHEM AL BI 1299 RARECHEM AN KA 0922

1of4

2,2-DIMETHYL-N-(4-PYRIDINYL)PROPANAMIDE 2,2-Dimethyl-N-pyridin-4-ylpropanamide 2,2-Dimethyl-N-(4-pyridinyl)propanamide ,97% N-(Pyridin-4-yl)pivalamide 4-(2,2,2-TriMethylacetaMido)pyridine, 97% N-(4-Pyridyl)pivalamide 4-(pivaloylamino)pyridine N-(4-Pyridyl)pivalamide> 2,2-Dimethyl-N-(4-pyridinyl)propanamid Propanamide, 2,2-dimethyl-N-4-pyridinyl- 2,2-Dimethyl-N-(4-pyridyl)propionamide 2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE ISO 9001：2015 REACH 2,2-Dimethyl-N-pyridin-4-yl- propionamide, 95% 2,2-Dimethyl-N-pyridin-4-yl-propionamide 70298-89-4 Amines Pyridines API intermediates