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ChemicalBook >> CAS DataBase List >>2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE Structure
2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE structure
CAS No.
70298-89-4
Chemical Name:
2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE
Synonyms
N-(4-Pyridyl)pivalamide;4-(pivaloylamino)pyridine;N-(4-Pyridyl)pivalamide>N-(Pyridin-4-yl)pivalamide;2,2-Dimethyl-N-(4-pyridinyl)propanamid;2,2-Dimethyl-N-pyridin-4-ylpropanamide;2,2-Dimethyl-N-(4-pyridyl)propionamide;2,2-DIMETHYL-N-(4-PYRIDINYL)PROPANAMIDE;Propanamide, 2,2-dimethyl-N-4-pyridinyl-;2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE
CBNumber:
CB0404822
Molecular Formula:
C10H14N2O
Molecular Weight:
178.23
MDL Number:
MFCD00996248
MOL File:
70298-89-4.mol
MSDS File:
SDS
Last updated:2026-05-27 21:54:49
Product description Number Pack Size Price
2,2-Dimethyl-N-pyridin-4-yl-propionamide Aldrich MNO000019 1g $68.1
N-(4-Pyridyl)pivalamide >98.0%(GC) P2044 1g $94
N-(4-Pyridyl)pivalamide >98.0%(GC) P2044 5g $277
N-(PYRIDIN-4-YL)PIVALAMIDE 95% AR2618 5G $39
2,2-Dimethyl-N-pyridin-4-yl-propionamide VCA29889 10g $354
More product size
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2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE Properties

Melting point 73.9-74.0°C
storage temp. Inert atmosphere,Room Temperature
solubility soluble in Methanol
form powder to crystal
color White to Almost white
InChI InChI=1S/C10H14N2O/c1-10(2,3)9(13)12-8-4-6-11-7-5-8/h4-7H,1-3H3,(H,11,12,13)
InChIKey JCMMVFHXRDNILC-UHFFFAOYSA-N
SMILES C(NC1C=CN=CC=1)(=O)C(C)(C)C
CAS DataBase Reference 70298-89-4

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
Hazard Codes  Xi,Xn
Risk Statements  22
HazardClass  IRRITANT
HS Code  29333990
NFPA 704
1
2 0

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE price More Price(74)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich MNO000019 2,2-Dimethyl-N-pyridin-4-yl-propionamide Aldrich 70298-89-4 1g $68.1 2023-01-07 Buy
TCI Chemical P2044 N-(4-Pyridyl)pivalamide >98.0%(GC) 70298-89-4 1g $94 2024-03-01 Buy
TCI Chemical P2044 N-(4-Pyridyl)pivalamide >98.0%(GC) 70298-89-4 5g $277 2024-03-01 Buy
AstaTech AR2618 N-(PYRIDIN-4-YL)PIVALAMIDE 95% 70298-89-4 5G $39 2026-04-30 Buy
Biosynth VCA29889 2,2-Dimethyl-N-pyridin-4-yl-propionamide 70298-89-4 10g $354 2026-06-05 Buy
Product number Packaging Price Buy
MNO000019 1g $68.1 Buy
P2044 1g $94 Buy
P2044 5g $277 Buy
AR2618 5G $39 Buy
VCA29889 10g $354 Buy

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE Chemical Properties,Uses,Production

Chemical Properties

Light yellow solid

Definition

ChEBI: 2,2-Dimethyl-N-(4-pyridinyl)propanamide is a dihydropyridine.

Synthesis

4-Aminopyridine

504-24-5

Pivaloyl chloride

3282-30-2

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE

70298-89-4

a) General procedure for the synthesis of 2,2-dimethyl-N-(pyridin-4-yl)propionamide: 4-Aminopyridine (2 g, 21.3 mmol) was dissolved in dichloromethane (20 ml), to which pentanoyl chloride (3.1 ml, 25.6 mmol) and triethylamine (8.9 ml, 63.9 mmol) were added sequentially dropwise at room temperature. The reaction mixture was stirred at room temperature for 15 h. The reaction was subsequently quenched by addition of water. The organic layer was extracted with ethyl acetate and the combined organic layers were washed with saturated sodium chloride solution (50 ml), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with dichloromethane:methanol (20:1, v/v) as eluent. The fraction containing the target product was collected and concentrated to afford N-(pyridin-4-yl)trimethylacetamide as a white solid (3.6 g, 95% yield).1H-NMR (CDCl3, 300 MHz) data were as follows: δ= 8.47 (d, J = 6.1 Hz, 2H), 7.79 (br s, 1H), 7.52 (d, J = 6.0 Hz, 2H), 7.52 (d, J = 6.0 Hz, 2H). 1.32 (s, 9H).

References

[1] Synthesis, 2009, # 13, p. 2267 - 2277
[2] Patent: US2011/28467, 2011, A1. Location in patent: Page/Page column 16
[3] Chemistry - A European Journal, 2013, vol. 19, # 20, p. 6435 - 6442
[4] Molecules, 2003, vol. 8, # 9, p. 678 - 686
[5] European Journal of Medicinal Chemistry, 2005, vol. 40, # 1, p. 15 - 23

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE synthesis

13534-98-0
70298-89-4
Synthesis of 2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE from 4-Amino-3-bromopyridine

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE Preparation Products And Raw materials

Raw materials

Hexane Sodium sulfate Triethylamine Pivaloyl chloride Sodium bicarbonate
Dichloromethane Methylcyclohexane Magnesium sulfate 4-Aminopyridine 4-Amino-3-bromopyridine
Pivalic acid

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Preparation Products

thiazolo[5,4-c]pyridine 4-Pivalamidopyridine-3-boronic acid N-(3-FORMYL-4-PYRIDINYL)-2,2-DIMETHYLPROPANAMIDE

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE Suppliers

Global( 136)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8828 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 20582 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
career henan chemical co 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
SIMAGCHEM CORP 		58
ANHUI WITOP BIOTECH CO., LTD 		58
Dideu Industries Group Limited 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Labnetwork lnc. 		58

View Lastest Price from 2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE pictures 2025-11-18 2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE
70298-89-4
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE pictures 2019-12-26 2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE
70298-89-4
 $1.00 1KG 99% 200kg Career Henan Chemical Co

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE Spectrum

2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE(70298-89-4)1HNMR

70298-89-4(2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE)Related Search:

4-[(2,2-DIMETHYLPROPANOYL)AMINO]NICOTINIC ACID 4-(2,2-DIMETHYL-PROPIONYLAMINO)-NICOTINIC ACID METHYL ESTER N-(3-IODO-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE N-(3-FORMYL-4-PYRIDINYL)-2,2-DIMETHYLPROPANAMIDE 2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE
N-(3-HYDROXY-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE 2,2-DIMETHYL-N-PYRIDIN-2-YL-PROPIONAMIDE Propionamide (PHENYLCYCLOPENTYL)-N-(4-PYRIDYL)FORMAMIDE N-(3-[1,3]DIOXOLAN-2-YL-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE
2,2-DIMETHYL-N-(3-TRIMETHYLSILANYL-PYRIDIN-4-YL)-PROPIONAMIDE N-(3-TERT-BUTYLSULFANYL-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE N-(3-DIMETHOXYMETHYL-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE 2,2-DIMETHYL-N-PYRIDIN-3-YL-PROPIONAMIDE 3-[4-(2,2-DIMETHYL-PROPIONYLAMINO)-PYRIDIN-3-YL]-ACRYLIC ACID ETHYL ESTER
RARECHEM AL BI 1299 RARECHEM AN KA 0922 N-(2-METHYL(4-QUINOLYL))(PHENYLCYCLOPENTYL)FORMAMIDE

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2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE 2,2-DIMETHYL-N-(4-PYRIDINYL)PROPANAMIDE 2,2-Dimethyl-N-pyridin-4-ylpropanamide 2,2-Dimethyl-N-(4-pyridinyl)propanamide ,97% N-(Pyridin-4-yl)pivalamide 4-(2,2,2-TriMethylacetaMido)pyridine, 97% N-(4-Pyridyl)pivalamide 4-(pivaloylamino)pyridine N-(4-Pyridyl)pivalamide> 2,2-Dimethyl-N-(4-pyridinyl)propanamid Propanamide, 2,2-dimethyl-N-4-pyridinyl- 2,2-Dimethyl-N-(4-pyridyl)propionamide 2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE ISO 9001：2015 REACH 2,2-Dimethyl-N-pyridin-4-yl- propionamide, 95% 70298-89-4 Amines Pyridines API intermediates