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Dimethyl acetylsuccinate

Dimethyl acetylsuccinate Structure
Dimethyl acetylsuccinate structure
CAS No.
10420-33-4
Chemical Name:
Dimethyl acetylsuccinate
Synonyms
DMAS;UNII:LOE57K9I2C;Dimethyl acetylsucci;Dimethylacylsuccinate;Dimethyl acetylsuccite;DIMETHYL ACETYLSUCCINATE;Doimethyl Acetylsuccinate;Dimethyl Acetylsuccinate >DiMethyl acetylsuccinate (DMAS);1,4-Dimethyl 2-acetyl-succinate
CBNumber:
CB0421498
Molecular Formula:
C8H12O5
Molecular Weight:
188.18
MDL Number:
MFCD00008448
MOL File:
10420-33-4.mol
MSDS File:
SDS
Last updated:2026-05-27 22:38:52
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Dimethyl acetylsuccinate Properties

Melting point 33 °C (lit.)
Boiling point 129-134 °C/12 mmHg (lit.)
Density 1.16 g/mL at 25 °C (lit.)
vapor pressure 19.6Pa at 25℃
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
solubility 30g/l OECD Test Guideline 105
pka 10.53±0.59(Predicted)
form solid
color White or Colorless to Almost white or Almost colorless
explosive limit 0.72-11.1%(V)
Water Solubility water: soluble 56.2g/L at20°C
InChI 1S/C8H12O5/c1-5(9)6(8(11)13-3)4-7(10)12-2/h6H,4H2,1-3H3
InChIKey XREKLQOUFWBSFH-UHFFFAOYSA-N
SMILES COC(=O)CC(C(C)=O)C(=O)OC
LogP 0.69 at 35℃ and pH7
CAS DataBase Reference 10420-33-4(CAS DataBase Reference)
FDA UNII LOE57K9I2C
EPA Substance Registry System Butanedioic acid, acetyl-, dimethyl ester (10420-33-4)
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
WGK Germany  1
TSCA  TSCA listed
HS Code  2918.30.7000
Storage Class 13 - Non Combustible Solids
REACH Registrations Active
NFPA 704
1
0 0

Dimethyl acetylsuccinate price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 280208 Dimethyl acetylsuccinate 10420-33-4 100g $218 2023-06-20 Buy
TCI Chemical A1143 Dimethyl Acetylsuccinate >96.0%(GC) 10420-33-4 25g $19 2026-04-30 Buy
TCI Chemical A1143 Dimethyl Acetylsuccinate >96.0%(GC) 10420-33-4 500g $118 2026-04-30 Buy
Biosynth KAA42033 Dimethyl Acetylsuccinate 10420-33-4 0.25g $250 2026-06-04 Buy
Biosynth KAA42033 Dimethyl Acetylsuccinate 10420-33-4 2.5g $855.5 2026-06-04 Buy
Product number Packaging Price Buy
280208 100g $218 Buy
A1143 25g $19 Buy
A1143 500g $118 Buy
KAA42033 0.25g $250 Buy
KAA42033 2.5g $855.5 Buy

Dimethyl acetylsuccinate Chemical Properties, Uses, Production

Uses

Dimethyl Acetylsuccinate was used in preparation of β-carbolines via diastereo- and enantioselective Bronsted acid catalyzed N-acyliminium cyclization cascades of tryptamines and keto acids/esters.

Uses

Dimethyl acetylsuccinate has been used in the synthesis of 2-oxofuro[2,3-b]pyrroles and 19-methyl-15-oxa-20-azatricyclo[12.3.3.0(1,14)]icos-18-en-18-carboxylates.

General Description

Dimethyl acetylsuccinate undergoes sulfuric acid catalyzed Pechmann condensation with the corresponding resorcinol derivative to give 7-hydroxycoumarins.

Dimethyl acetylsuccinate Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl (6-chloro-7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate

Dimethyl acetylsuccinate Suppliers

Global Suppliers ( 209)
Supplier Tel Email Country ProdList Advantage
Guangdong Fangxin Biotechnology Co., Ltd. 0751-2838688 13376594225 1276075424@qq.com China 9930 58
Jinan Wanduoxin Chemical Co., Ltd. 0531-88770993 13905318421 wonderfulchem@163.com China 268 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16306 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Supplier Advantage
Guangdong Fangxin Biotechnology Co., Ltd. 58
Jinan Wanduoxin Chemical Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Adamas Reagent, Ltd. 59
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64

View Latest Price from Dimethyl acetylsuccinate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dimethyl acetylsuccinate pictures 2026-06-30 Dimethyl acetylsuccinate
10420-33-4
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
Dimethyl acetylsuccinate pictures 2021-08-12 Dimethyl acetylsuccinate
10420-33-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
Dimethyl acetylsuccinate pictures 2019-12-27 Dimethyl acetylsuccinate
10420-33-4
 $1.00 1g 99% 10000KGS Career Henan Chemical Co

Dimethyl acetylsuccinate Spectrum

Dimethyl acetylsuccinate(10420-33-4)MSDimethyl acetylsuccinate(10420-33-4)1HNMRDimethyl acetylsuccinate(10420-33-4)13CNMRDimethyl acetylsuccinate(10420-33-4)IR1Dimethyl acetylsuccinate(10420-33-4)Raman

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acetyl-butanedioicaciddimethylester acetyl-butanedioicacidimethylester ACETYLSUCCINIC ACID DIMETHYL ESTER DIMETHYL ACETYLSUCCINATE BUTANEDIOIC ACID, ACETYL-DIMETHYL ESTER BUTANDIOIC ACID ACETYL-DIMETHYLESTER Doimethyl Acetylsuccinate 3-carboxy-4-oxopentanoic acid dimethyl ester 2-Acetylbutanedioic acid dimethyl ester DiMethyl acetylsuccinate (DMAS) DIMETHYL ACETYLSUCCINATE FOR SYNTHESIS 2-Acetylbutanedioic acid-1,4-dimethyl ester 2-Acetyl-succinic acid dimethyl ester Dimethyl acetylsuccite Dimethyl acetylsucci Dimethyl Acetylsuccinate > 10420-33-4 Dimethyl acetylsuccinate UNII:LOE57K9I2C Dimethylacylsuccinate 1,4-Dimethyl 2-acetyl-succinate DMAS 10420-33-4 CH3O2CCH2CHCOCH3CO2CH3 Organic Building Blocks Esters Building Blocks C8 to C9 Carbonyl Compounds Pharmaceutical Intermediates C8 to C9 Carbonyl Compounds Esters bc0001