Dimethyl succinate
- CAS No.
- 106-65-0
- Chemical Name:
- Dimethyl succinate
- Synonyms
- FEMA 2396;DIMETHYL BUTANEDIOATE;METHYL SUCCINATE;DBE-4 DIBASIC ESTER;Succinic acid dimethyl;Dimethyl 2,3-butanedioate;SUCCINIC ACID DIMETHYL ESTER;DBE-4 DIBASIC ESTER, 99% (DIMETHYL SUCCI NATE);DBE-4;ESTASOL(R)
- CBNumber:
- CB9230712
- Molecular Formula:
- C6H10O4
- Molecular Weight:
- 146.14
- MDL Number:
- MFCD00008466
- MOL File:
- 106-65-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 16-19 °C (lit.) |
|---|---|
| Boiling point | 200 °C (lit.) |
| Density | 1.117 g/mL at 25 °C (lit.) |
| vapor pressure | 0.3 mm Hg ( 20 °C) |
| refractive index |
n |
| FEMA | 2396 | DIMETHYL SUCCINATE |
| FLAVIS Number | 09.445 | Dimethyl succinate |
| Flash point | 185 °F |
| storage temp. | Store below +30°C. |
| solubility | 75g/l |
| form | Liquid |
| color | Clear |
| Odor | Fruity |
| Odor Type | fruity |
| biological source | synthetic |
| Viscosity |
2.920 [MPAS] AT 20°C 1.816 [MPAS] AT 40°C 1.410 [MPAS] AT 60°C 1.133 [MPAS] AT 80°C |
| explosive limit | 1.0-8.5%(V) |
| Water Solubility | 8.5 g/L (20 ºC) |
| Merck | 14,8869 |
| JECFA Number | 616 |
| BRN | 956776 |
| Henry's Law Constant | 3.0×101 mol/(m3Pa) at 25℃, Katrib et al. (2003) |
| Dielectric constant | 5.1(20℃) |
| Stability | Stable. Combustible. Incompatible with oxidizing agents, acids, bases, reducing agents. |
| Major Application | flavors and fragrances |
| Cosmetics Ingredients Functions |
SKIN CONDITIONING - EMOLLIENT SOLVENT FRAGRANCE SKIN CONDITIONING |
| Cosmetic Ingredient Review (CIR) | Dimethyl succinate (106-65-0) |
| InChI | 1S/C6H10O4/c1-9-5(7)3-4-6(8)10-2/h3-4H2,1-2H3 |
| InChIKey | MUXOBHXGJLMRAB-UHFFFAOYSA-N |
| SMILES | COC(=O)CCC(=O)OC |
| LogP | 0.33 at 40℃ |
| CAS DataBase Reference | 106-65-0(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | DIMETHYL SUCCINATE |
| FDA 21 CFR | 172.515 |
| EWG's Food Scores | 1 |
| FDA UNII | 914I2127JR |
| NIST Chemistry Reference | Butanedioic acid, dimethyl ester(106-65-0) |
| EPA Substance Registry System | Dimethyl succinate (106-65-0) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36 | |||||||||
| Safety Statements | 26-24/25 | |||||||||
| RIDADR | UN 1993 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | WM7675000 | |||||||||
| Autoignition Temperature | 689 °F | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29171990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| Hazardous Substances Data | 106-65-0(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Dimethyl succinate price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W239607 | Dimethyl succinate 98%, FG | 106-65-0 | 1 each | $58 | 2026-04-30 | Buy |
| Sigma-Aldrich | W239607 | Dimethyl Succinate 98%, FG | 106-65-0 | 1kg | $81.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | W239607 | Dimethyl Succinate 98%, FG | 106-65-0 | 10Kg | $487 | 2026-04-30 | Buy |
| Sigma-Aldrich | W239607 | Dimethyl Succinate 98%, FG | 106-65-0 | 25kg | $861 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.20150 | Dimethyl succinate for synthesis | 106-65-0 | 250ML | $55.7 | 2026-04-30 | Buy |
Dimethyl succinate Chemical Properties,Uses,Production
Description
Dimethyl succinate belong to the diester of methyl alcohol and succinic acid, which can be found in nuts. It is a biodegradable ester with low odor and low volatility and commonly serves as a flavoring agent that can be used in perfumery and personal are products, including skin-conditioning agents and emollient. It also has a variety of industrial usages such as functional fluids (open systems), intermediates, paint additives and coating additives, pigments, viscosity adjustors, etc. Besides, dimethyl succinate can be used in the production of pharmaceuticals as well as agrochemicals and for manufacturing additives, plastics and other organic compounds. In spite of its slightly water-soluble property, it can also act as a surfactant applied in water based systems.
References
http://www.chemicalland21.com/specialtychem/perchem/DIMETHYL%20SUCCINATE.htm
https://www.ewg.org/skindeep/ingredient/702064/DIMETHYL_SUCCINATE/
https://www.alfa.com/zh-cn/catalog/A12565/
https://pubchem.ncbi.nlm.nih.gov/compound/7820#section=Consumer-Uses
Chemical Properties
Dimethyl succinate is colorless to light yellow liquid and has a pleasant, ethereal, winy odor and fruity, winy and burning flavor. slightly soluble in water (1%), soluble in ethanol (3%), miscible in oil. Natural product exists in fried hazelnuts. It is used as a solvent in paints, lacquers, varnishes, nitrocellulose, paint strippers, dyes, fats, photography, and waxes. It is also used in the manufacture of other succinates.
Occurrence
Reported found in filbert nuts and starfruit.
Uses
Dimethyl succinate is used as a flavoring agent. It have wide range of industrial applications such as Functional fluids (open systems), Intermediates, Paint additives and coating additives, Pigments Solvents, Viscosity adjustors.
Definition
ChEBI: Dimethyl succinate is a fatty acid methyl ester.
Preparation
By direct esterification of the acid with the alcohol in benzene solution at the boil in the presence of concentrated H2SO4
Taste threshold values
Taste characteristics at 0.1%: sweet, fruity, green with a soapy, waxy nuance
Synthesis Reference(s)
Journal of the American Chemical Society, 100, p. 1119, 1978 DOI: 10.1021/ja00472a016
The Journal of Organic Chemistry, 59, p. 3500, 1994 DOI: 10.1021/jo00091a050
General Description
Colorless liquid.
Air & Water Reactions
Water soluble.
Reactivity Profile
Dimethyl succinate reacts with acids to liberate heat along with methanol and succinic acid. May react with strong oxidizing acids to liberate enough heat to ignite the reaction products. Heat is also generated by the interaction with caustic solutions. Flammable hydrogen is generated with alkali metals and hydrides.
Health Hazard
May be harmful by inhalation, ingestion or skin absorption. May cause irritation.
Fire Hazard
Dimethyl succinate is combustible. Vapor forms explosive mixtures with air.
Toxics Screening Level
All screening levels for DBE, including the new ITSL of 1 μg/m3 (annual) are based on a 90-day inhalation study Keenan et a/.(1990), which identified a lowest-observed-adverse-effect-level (LOAEL) of 20 mg/m3 for degeneration of nasal epithelium in female rats. Up to this time, the individual dimethyl esters each had ITSLs of 0.1 μg/m3 (annual).
Dimethyl succinate Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hanyang Chemical Products Co., Ltd. | 18063541133 18063541133 | zhangzhen198705@sina.com | China | 496 | 58 |
| Shanghai Ditao Chemical Technology Co., Ltd. | 021-37122200 17717569696 | sales@ditaochem.com | China | 308 | 58 |
| Shandong flying Chemical Co., Ltd | 18954855616 | 920481088@qq.com | China | 33 | 58 |
| Zhongshan Dixin Chemical Co., Ltd | 19849939632; 19849939632 | 2470479589@qq.com | China | 1748 | 58 |
| Tenghong (Shandong) New Material Co., Ltd | 1555-2555846 18265060865 | 1277177917@qq.com | China | 2793 | 58 |
| Shandong Xinhecheng Chemical Co., Ltd | 18660169893 | xiaofeiyu1319@126.com | China | 268 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
View Lastest Price from Dimethyl succinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-12 | Dimethyl succinate
106-65-0
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-07-17 | Dimethyl succinate
106-65-0
|
$40.00 | 98.00% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-06-30 | Dimethyl succinate
106-65-0
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd |
-
- Dimethyl succinate
106-65-0
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Dimethyl succinate
106-65-0
- $40.00
- 98.00%
- TargetMol Chemicals Inc.
-
- Dimethyl succinate
106-65-0
- 98%
- Shaanxi Dideu New Materials Co. Ltd
