3,5-Dimethylphenol
- CAS No.
- 108-68-9
- Chemical Name:
- 3,5-Dimethylphenol
- Synonyms
- MSDS;3,5-XYLENOL;3,5-Dmp;Phenol,3,5-dimethyl-;SYM-M-XYLENOL;5-DiMethylphenol;DIMETHYLPHENOL(3,5-);NSC-9268;M-XYLENOL;ai3-01553
- CBNumber:
- CB0426150
- Molecular Formula:
- C8H10O
- Molecular Weight:
- 122.16
- MDL Number:
- MFCD00002307
- MOL File:
- 108-68-9.mol
- MSDS File:
- SDS
| Melting point | 61-64 °C(lit.) |
|---|---|
| Boiling point | 222 °C(lit.) |
| Density | 1.115 |
| vapor pressure | 5-5.4Pa at 25℃ |
| FLAVIS Number | 04.020 | 3,5-Dimethylphenol |
| refractive index | 1.5146 (estimate) |
| Flash point | 109 °C |
| storage temp. | room temp |
| form | Crystalline Solid |
| pka | pK1:10.15 (25°C) |
| color | White to orange |
| Odor | Strong, “cresylic” odor. |
| Water Solubility | 5.3 g/L (25 ºC) |
| Sensitive | Air & Light Sensitive |
| Merck | 14,10082 |
| BRN | 774117 |
| Henry's Law Constant | 1.5×101 mol/(m3Pa) at 25℃, Brockbank (2013) |
| Exposure limits | ACGIH: TWA 1 ppm |
| InChI | 1S/C8H10O/c1-6-3-7(2)5-8(9)4-6/h3-5,9H,1-2H3 |
| InChIKey | TUAMRELNJMMDMT-UHFFFAOYSA-N |
| SMILES | Cc1cc(C)cc(O)c1 |
| LogP | 2.35 at 25.5℃ |
| CAS DataBase Reference | 108-68-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | ONA760G0WA |
| NIST Chemistry Reference | Phenol, 3,5-dimethyl-(108-68-9) |
| EPA Substance Registry System | 3,5-Dimethylphenol (108-68-9) |
| UNSPSC Code | 41116107 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311-H314-H402 | |||||||||
| Precautionary statements | P501-P273-P260-P270-P264-P280-P361+P364-P303+P361+P353-P301+P330+P331-P301+P310+P330-P304+P340+P310-P305+P351+P338+P310-P405 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 24/25-34 | |||||||||
| Safety Statements | 26-28-36/37/39-45-28A | |||||||||
| RIDADR | UN 2261 6.1/PG 2 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | ZE6475000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29071400 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
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| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Oral Eye Dam. 1 Skin Corr. 1B |
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| Hazardous Substances Data | 108-68-9(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 0.5 Kg (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (1g or 1ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
3,5-Dimethylphenol price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 144134 | 3,5-Dimethylphenol ≥99% | 108-68-9 | 100g | $57.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 144134 | 3,5-Dimethylphenol ≥99% | 108-68-9 | 5g | $35.4 | 2024-03-01 | Buy |
| TCI Chemical | D0778 | 3,5-Dimethylphenol >99.0%(GC) | 108-68-9 | 25g | $42 | 2024-03-01 | Buy |
| TCI Chemical | D0778 | 3,5-Dimethylphenol >99.0%(GC) | 108-68-9 | 500g | $445 | 2024-03-01 | Buy |
| TRC | TRC-X749505-10G | 3,5-Dimethylphenol | 108-68-9 | 10g | $185 | 2026-06-03 | Buy |
3,5-Dimethylphenol Chemical Properties, Uses, Production
Description
3,5-Dimethylphenol was used in simultaneous determination of urinary concentrations of phenol, o-, p-, m-cresols, 1-, 2-naphthol and xylenol isomers by capillary gas chromatography. It was used as starting reagent for total synthesis of landomycin A, most potent antitumor angucycline antibiotic and optically active polypropionate units. It also finds application as adhesives, sealant chemicals, plating and surface treating agents. It is also used as a solvent for cleaning or degreasing. Further, it is employed as a chemical intermediate for antioxidants, phenolic resins, active pharmaceutical ingredients and metaxalone (muscle relaxant).
Description
3,5-Xylenol is a crystalline solid. Molecularweight 5 122.17; Boiling point= 220℃ (sublimes);Freezing/Melting point=64℃; Flash point = 109℃.Soluble in water. Hazard Identification (based on NFPA-704 M Rating System): Health 3, Flammability 2, Reactivity0. Slightly soluble in water; solubility =0.5%.
Chemical Properties
3,5-Xylenol is a crystalline solid.
Uses
3,5-Dimethylphenol finds application as adhesives, sealant chemicals, plating and surface treating agents. It is also used as a solvent for cleaning or degreasing. Further, it is employed as a chemical intermediate for antioxidants, phenolic resins, active pharmaceutical ingredients and metaxalone (muscle relaxant).
Definition
ChEBI: A member of the class of phenols that phenol substituted by methyl groups at positions 3 and 5.
General Description
Colorless to off-white crystalline solid. Odor threshold 1 ppm. Taste threshold 0.001 mg/L.
Air & Water Reactions
3,5-Dimethylphenol is hygroscopic. Insoluble in water.
Reactivity Profile
3,5-Dimethylphenol is incompatible with bases, acid chlorides, acid anhydrides, and oxidizing agents. 3,5-Dimethylphenol corrodes steel, brass, copper, and copper alloys.
Fire Hazard
Flash point data for 3,5-Dimethylphenol are not available. 3,5-Dimethylphenol is probably combustible.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. A severe eye irritant. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also other xylenol entries.
Potential Exposure
3,5-Xylenol is used as an antioxidant, solvent, plasticizer, wetting agent; and in pharmaceuticals. Xylenols are also used in pesticides, fuel, and lubricant additives; as a rubber chemical; in dyestuff manufacture. There are actually six xylenol isomers.
First aid
Get medical attention at once following exposureto this compound.Inhalation: Remove patient immediately to fresh air; irritation of nose or throat may be somewhat relieved by spraying or gargling with water until all odor is gone; 100%oxygen inhalation is indicated for cyanosis or respiratorydistress; keep patient warm but not hot.Eyes: Flood with running water for 15 min; if physician isnot immediately available, continue irrigation for another15 min; 2-3 drops of 0.5% pontocaine or equivalent maybe instilled after first 15 min; do not use oils or oily ointments unless ordered by physician.Skin: Wash affected areas with large quantities of water orsoapy water until all odor is gone; then wash with alcoholor 20% glycerin solution and more water; keep patientwarm but not hot; cover chemical burns continuously withcompresses wet with saturated solution of sodium thiosulfate; apply no salves or ointments for 24 h after injury.Ingestion: Give large quantities of liquid (saltwater, weaksodium bicarbonate solution, milk, or gruel) followed bydemulcent, such as raw egg white or corn starch paste; ifprofuse vomiting does not follow immediately, give a mildemetic (such as 1 tablespoon of mustard in glass of water)or tickle back of throat. Repeat procedure until vomitus isfree of the odor. Some demulcent should be left in stomachafter vomiting. Keep patient comfortably warm.
storage
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area away from chemical oxidizers. Sources ofignition, such as smoking and open flames, are prohibitedwhere xylenols is used, handled, or stored in a manner thatcould create a potential fire or explosion hazard.
Shipping
UN 2261 Xylenols, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Purification Methods
Purify it as for 3,4-dimethylphenol. [Beilstein 6 IV 3141.]
Incompatibilities
A weak organic acid. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides.
Toxics Screening Level
The initial threshold screening level for 3,5-dimethylphenol is being set at 0.8 μg/m3 with annual averaging.
Waste Disposal
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.
3,5-Dimethylphenol Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Powerful Chemical (Shanghai) Co., Ltd. | 021-62211590 18917958225; | pwfchem@163.com | China | 75 | 58 |
| Changzhou Junchi Chemical Co.,ltd. | 0519-85518211 15195021697 | 85518211@chemjunchi.com | China | 64 | 58 |
| Shandong Mingde Biotechnology Co., Ltd | 15564477061 | 1397986535@qq.com | China | 272 | 58 |
| Nanjing Datang Chemical Co., Ltd | 025-85431992 13951889900 | vip@chemdatang.com | China | 100 | 66 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
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- Application and preparation of 3,5-dimethylphenol
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- Oct 13,2022
View Latest Price from 3,5-Dimethylphenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | 3,5-Dimethylphenol
108-68-9
|
1KG | 99% | 500mt | Jinan Finer Chemical Co., Ltd | ||
 |
2026-05-28 | 3,5-Dimethylphenol
108-68-9
|
$9.00 | 1KG | 99.9 | 1 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-03-20 | 3,5-Dimethylphenol
108-68-9
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 3,5-Dimethylphenol
108-68-9
- $0.00
- 99%
- Jinan Finer Chemical Co., Ltd
-
- 3,5-Dimethylphenol
108-68-9
- $9.00
- 99.9
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 3,5-Dimethylphenol
108-68-9
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
