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3,5-Dimethoxyphenol

3,5-Dimethoxyphenol Structure
3,5-Dimethoxyphenol structure
CAS No.
500-99-2
Chemical Name:
3,5-Dimethoxyphenol
Synonyms
Phenol, 3,5-dimethoxy-;NSC 70955;Taxicatigenin;3,5-DIMETHOXYPHENOL;3,5-Dimethoxyphenol>3,5-DiMethoxyphenol 99%;3,5-Dimethoxyphenol,97%;DIMETHOXYPHENOL, 3,5-(P);Phloroglucinol Impurity 24;Phloroglucin dimethyl ether
CBNumber:
CB2268778
Molecular Formula:
C8H10O3
Molecular Weight:
154.16
MDL Number:
MFCD00008388
MOL File:
500-99-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 19:39:08
Product description Number Pack Size Price
3,5-Dimethoxyphenol 99% 132632 10g $116
3,5-Dimethoxyphenol 99% 132632 50g $301
3,5-Dimethoxyphenol >98.0%(GC) P0320 25g $137
3,5-Dimethoxyphenol >98.0%(GC) P0320 100g $369
3,5-Dimethoxyphenol ≥98%(GC) 00347 5G $30.35
More product size
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3,5-Dimethoxyphenol Properties

Melting point 40-43 °C (lit.)
Boiling point 172-175 °C/17 mmHg (lit.)
Density 1.1690 (rough estimate)
refractive index 1.4745 (estimate)
Flash point 173 °F
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka pK1:9.345 (25°C)
form Liquid
color Clear colorless to orange-red to pale pink-brownish
Water Solubility Soluble in methanol, ethanol, benzene, water (slightly), and chloroform.
Sensitive Air & Light Sensitive
BRN 1239156
InChI 1S/C8H10O3/c1-10-7-3-6(9)4-8(5-7)11-2/h3-5,9H,1-2H3
InChIKey XQDNFAMOIPNVES-UHFFFAOYSA-N
SMILES COc1cc(O)cc(OC)c1
LogP 1.640
CAS DataBase Reference 500-99-2(CAS DataBase Reference)
FDA UNII 23UXW8136A
NIST Chemistry Reference Phenol, 3,5-dimethoxy-(500-99-2)
EPA Substance Registry System Phenol, 3,5-dimethoxy- (500-99-2)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
F  10
Hazard Note  Irritant
HS Code  29095090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

3,5-Dimethoxyphenol price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 132632 3,5-Dimethoxyphenol 99% 500-99-2 10g $116 2026-04-30 Buy
Sigma-Aldrich 132632 3,5-Dimethoxyphenol 99% 500-99-2 50g $301 2026-04-30 Buy
TCI Chemical P0320 3,5-Dimethoxyphenol >98.0%(GC) 500-99-2 25g $137 2026-04-30 Buy
TCI Chemical P0320 3,5-Dimethoxyphenol >98.0%(GC) 500-99-2 100g $369 2026-04-30 Buy
Chem-Impex 00347 3,5-Dimethoxyphenol ≥98%(GC) 500-99-2 5G $30.35 2026-05-19 Buy
Product number Packaging Price Buy
132632 10g $116 Buy
132632 50g $301 Buy
P0320 25g $137 Buy
P0320 100g $369 Buy
00347 5G $30.35 Buy

3,5-Dimethoxyphenol Chemical Properties,Uses,Production

Chemical Properties

slightly pink to yellow crystalline powder

Uses

3,5-Dimethoxyphenol is a phenol derivative as antinitrosating agent.

Uses

3,5-dimethoxyphenol is a marker for poisoning from Taxus baccata.

Definition

ChEBI: 3,5-Dimethoxyphenol is a member of methoxybenzenes and a member of phenols.

Synthesis

Ethanethiol (1.25g, 1.5 ml, 0.02 mole) dissolved in N, N- dimethyl-formamide (20 ml) is added to a suspension of sodium hydride (1 g of 50%oil dispersion) in dry DMF (10 ml) under an atmosphere of nitrogen. The mixture is stirred for 5 min under anhydrous conditions. A solution of phloroglucinol trimethyl ether (1.14) (1 g,0.006 moles) in dry DMF (10 ml)is added, and the mixture is refluxed for 3 hr. The reaction mixture is cooled and acidified with hydrochloric acid (10%). It is extracted with ether(3 x 50 ml). The ether extract is washed with water and extracted with sodium hydroxide solution (5%). The clear alkaline extract is acidified with hydrochloric acid. The mixture is extracted with ether. The ether extract is washed with water, ried (anhydrous sodium sulphate), and drilled. 3,5-Dimethoxyphenol is obtained as an oil. Yield 0.9 g (98.1%).B.p.198-199°/30 mm.
3,5-Dimethoxyphenol

Purification Methods

Purify the phenol by distillation followed by sublimation in a vacuum. [Beilstein 6 IV 7362.]

3,5-Dimethoxyphenol Preparation Products And Raw materials

Raw materials

Preparation Products

4-Hydroxy-2,6-dimethoxybenzaldehyde 1-(6-hydroxy-2,4-dimethoxy-3-methylphenyl)ethanone 4,6-DIMETHOXYSALICYLALDEHYDE Pinostrobin 5,7-Dimethoxycoumarin
3,5-Dimethoxybenzylamine 3-(3,5-dimethoxyphenoxy)propanoic acid 2-(3-(3,5-Dimethoxyphenoxy)Propyl)Isoindoline-1,3-Dione 5,7-DIMETHOXY-2-METHYL-2-PHENYL-CHROMAN-4-ONE

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3,5-Dimethoxyphenol Suppliers

Global( 319)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Wish Pharma Co., Ltd
+86-021-56789108 +8615021138722 Wishpharma0713@gmail.com China 22 58
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29816 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
Supplier Advantage
Shanghai Wish Pharma Co., Ltd
58
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Chengdu Biopurify Phytochemicals Ltd. 		58
Standardpharm Co. Ltd. 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
TargetMol Chemicals Inc. 		58

View Lastest Price from 3,5-Dimethoxyphenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-Dimethoxyphenol pictures 2026-05-14 3,5-Dimethoxyphenol
500-99-2
 US $0.00-0.00 / kg 0.5kg Minimum 95% 300kg Shanghai Wish Pharma Co., Ltd
3,5-Dimethoxyphenol pictures 2026-05-11 3,5-Dimethoxyphenol
500-99-2
 US $29.00 / g 98.00% 10g TargetMol Chemicals Inc.
3,5-Dimethoxyphenol pictures 2022-02-19 3,5-Dimethoxyphenol
500-99-2
 US $0.00 / KG 1KG 97.0% 100 tons Honest Joy Holdings Limited

3,5-Dimethoxyphenol Spectrum

3,5-Dimethoxyphenol(500-99-2)MS3,5-Dimethoxyphenol(500-99-2)1HNMR3,5-Dimethoxyphenol(500-99-2)13CNMR3,5-Dimethoxyphenol(500-99-2)IR13,5-Dimethoxyphenol(500-99-2)Raman

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PHLOROGLUCINOL DIMETHYL ETHER 3,5-DIMETHOXYPHENOL 1-Hydroxy-3,5-dimethoxybenzene Taxicatigenin 3,5-Dimethoxy Phenol, 98%min 3,5-DIMETHYOXY PHENYL HYDROXIDE Phenol, 3,5-dimethoxy- Phloroglucinol Impurity 24 DIMETHOXYPHENOL, 3,5-(P) 3,5-DiMethoxyphenol 99% Phloroglucin dimethyl ether 3,5-Dimethoxyphenol,97% 3,5-Dimethoxyphenol≥ 98% (GC) 3,5-Dimethoxyphenol,Phloroglucinol dimethyl ether NSC 70955 3,5-Dimethoxyphenol> 3,5-Dimethoxyphenol in methanol 500-99-2 CH3O2C6H3OH Building Blocks Organic Building Blocks Oxygen Compounds Phenols Aromatic Ethers Building Blocks C6 to C8 Chemical Synthesis Organic Building Blocks Oxygen Compounds Phenols