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3,5-Dimethoxyphenol

3,5-Dimethoxyphenol Structure
3,5-Dimethoxyphenol structure
CAS No.
500-99-2
Chemical Name:
3,5-Dimethoxyphenol
Synonyms
Phenol, 3,5-dimethoxy-;NSC 70955;Taxicatigenin;3,5-DIMETHOXYPHENOL;3,5-Dimethoxyphenol>3,5-DiMethoxyphenol 99%;3,5-Dimethoxyphenol,97%;DIMETHOXYPHENOL, 3,5-(P);Phloroglucinol Impurity 24;Phloroglucin dimethyl ether
CBNumber:
CB2268778
Molecular Formula:
C8H10O3
Molecular Weight:
154.16
MDL Number:
MFCD00008388
MOL File:
500-99-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
3,5-Dimethoxyphenol 99% 132632 10g $116
3,5-Dimethoxyphenol 99% 132632 50g $301
3,5-Dimethoxyphenol >98.0%(GC) P0320 25g $137
3,5-Dimethoxyphenol >98.0%(GC) P0320 100g $369
3,5-Dimethoxyphenol 98+% (GC) ≥98%(GC) 232321 5g $170
More product size
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3,5-Dimethoxyphenol Properties

Melting point 40-43 °C (lit.)
Boiling point 172-175 °C/17 mmHg (lit.)
Density 1.1690 (rough estimate)
refractive index 1.4745 (estimate)
Flash point 173 °F
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka pK1:9.345 (25°C)
form Liquid
color Clear colorless to orange-red to pale pink-brownish
Water Solubility Soluble in methanol, ethanol, benzene, water (slightly), and chloroform.
Sensitive Air & Light Sensitive
BRN 1239156
InChI 1S/C8H10O3/c1-10-7-3-6(9)4-8(5-7)11-2/h3-5,9H,1-2H3
InChIKey XQDNFAMOIPNVES-UHFFFAOYSA-N
SMILES COc1cc(O)cc(OC)c1
LogP 1.640
CAS DataBase Reference 500-99-2(CAS DataBase Reference)
FDA UNII 23UXW8136A
NIST Chemistry Reference Phenol, 3,5-dimethoxy-(500-99-2)
EPA Substance Registry System Phenol, 3,5-dimethoxy- (500-99-2)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
F  10
Hazard Note  Irritant
HS Code  29095090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

3,5-Dimethoxyphenol price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 132632 3,5-Dimethoxyphenol 99% 500-99-2 10g $116 2026-04-30 Buy
Sigma-Aldrich 132632 3,5-Dimethoxyphenol 99% 500-99-2 50g $301 2026-04-30 Buy
TCI Chemical P0320 3,5-Dimethoxyphenol >98.0%(GC) 500-99-2 25g $137 2026-04-30 Buy
TCI Chemical P0320 3,5-Dimethoxyphenol >98.0%(GC) 500-99-2 100g $369 2026-04-30 Buy
Usbiological 232321 3,5-Dimethoxyphenol 98+% (GC) ≥98%(GC) 5g $170 2026-06-03 Buy
Product number Packaging Price Buy
132632 10g $116 Buy
132632 50g $301 Buy
P0320 25g $137 Buy
P0320 100g $369 Buy
232321 5g $170 Buy

3,5-Dimethoxyphenol Chemical Properties,Uses,Production

Chemical Properties

slightly pink to yellow crystalline powder

Uses

3,5-Dimethoxyphenol is a phenol derivative as antinitrosating agent.

Uses

3,5-dimethoxyphenol is a marker for poisoning from Taxus baccata.

Definition

ChEBI: 3,5-Dimethoxyphenol is a member of methoxybenzenes and a member of phenols.

Synthesis

Ethanethiol (1.25g, 1.5 ml, 0.02 mole) dissolved in N, N- dimethyl-formamide (20 ml) is added to a suspension of sodium hydride (1 g of 50%oil dispersion) in dry DMF (10 ml) under an atmosphere of nitrogen. The mixture is stirred for 5 min under anhydrous conditions. A solution of phloroglucinol trimethyl ether (1.14) (1 g,0.006 moles) in dry DMF (10 ml)is added, and the mixture is refluxed for 3 hr. The reaction mixture is cooled and acidified with hydrochloric acid (10%). It is extracted with ether(3 x 50 ml). The ether extract is washed with water and extracted with sodium hydroxide solution (5%). The clear alkaline extract is acidified with hydrochloric acid. The mixture is extracted with ether. The ether extract is washed with water, ried (anhydrous sodium sulphate), and drilled. 3,5-Dimethoxyphenol is obtained as an oil. Yield 0.9 g (98.1%).B.p.198-199°/30 mm.
3,5-Dimethoxyphenol

Purification Methods

Purify the phenol by distillation followed by sublimation in a vacuum. [Beilstein 6 IV 7362.]

3,5-Dimethoxyphenol Preparation Products And Raw materials

Raw materials

Preparation Products

4-Hydroxy-2,6-dimethoxybenzaldehyde 1-(6-hydroxy-2,4-dimethoxy-3-methylphenyl)ethanone 4,6-DIMETHOXYSALICYLALDEHYDE Pinostrobin 5,7-Dimethoxycoumarin
3,5-Dimethoxybenzylamine 3-(3,5-dimethoxyphenoxy)propanoic acid 2-(3-(3,5-Dimethoxyphenoxy)Propyl)Isoindoline-1,3-Dione 5,7-DIMETHOXY-2-METHYL-2-PHENYL-CHROMAN-4-ONE

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3,5-Dimethoxyphenol Suppliers

Global( 323)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29766 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +86-18080483897 sales@biopurify.com China 4616 58
CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14301 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-17392587031 1059@dideu.com China 9984 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 sales@sarms4muscle.com China 10378 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
career henan chemical co 		58
Chengdu Biopurify Phytochemicals Ltd. 		58
CONIER CHEM AND PHARMA LIMITED 		58
TargetMol Chemicals Inc. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Win-Win chemical CO., Limited 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Zhejiang J&C Biological Technology Co.,Limited 		58

View Lastest Price from 3,5-Dimethoxyphenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-Dimethoxyphenol pictures 2026-08-08 3,5-Dimethoxyphenol
500-99-2
 $29.00 98.00% 10g TargetMol Chemicals Inc.
3,5-Dimethoxyphenol pictures 2026-05-14 3,5-Dimethoxyphenol
500-99-2
 Minimum 95% 300kg Shanghai Wish Pharma Co., Ltd
3,5-Dimethoxyphenol pictures 2022-02-19 3,5-Dimethoxyphenol
500-99-2
 1KG 97.0% 100 tons Honest Joy Holdings Limited

3,5-Dimethoxyphenol Spectrum

3,5-Dimethoxyphenol(500-99-2)MS3,5-Dimethoxyphenol(500-99-2)1HNMR3,5-Dimethoxyphenol(500-99-2)13CNMR3,5-Dimethoxyphenol(500-99-2)IR13,5-Dimethoxyphenol(500-99-2)Raman

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PHLOROGLUCINOL DIMETHYL ETHER 3,5-DIMETHOXYPHENOL 1-Hydroxy-3,5-dimethoxybenzene Taxicatigenin 3,5-Dimethoxy Phenol, 98%min 3,5-DIMETHYOXY PHENYL HYDROXIDE Phenol, 3,5-dimethoxy- Phloroglucinol Impurity 24 DIMETHOXYPHENOL, 3,5-(P) 3,5-DiMethoxyphenol 99% Phloroglucin dimethyl ether 3,5-Dimethoxyphenol,97% 3,5-Dimethoxyphenol≥ 98% (GC) 3,5-Dimethoxyphenol,Phloroglucinol dimethyl ether NSC 70955 3,5-Dimethoxyphenol> 3,5-Dimethoxyphenol in methanol 500-99-2 CH3O2C6H3OH Building Blocks Organic Building Blocks Oxygen Compounds Phenols Aromatic Ethers Building Blocks C6 to C8 Chemical Synthesis Organic Building Blocks Oxygen Compounds Phenols