CI 15511
- CAS No.
- 131-28-2
- Chemical Name:
- CI 15511
- Synonyms
- NARCEINE;NARCEIN;CI 15511;NIH 10760;henyl)acetyl)-;CI 15511，Narceine;Narceine (base and/or unspecified salts);4-(methylenedioxy)phenyl)acetyl)-6-((6-(2-(dimethylamino)ethyl)-2-methoxy-;o-veratricacid,6-((6-(2-(dimethylamino)ethyl)-2-methoxy-3,4-(methylenedioxy)p;4-[2-(2-Hydroxy-1-naphtyl)-2-sodiosulfohydrazino]benzenesulfonic acid sodium salt
- CBNumber:
- CB0445649
- Molecular Formula:
- C23H27NO8
- Molecular Weight:
- 445.46
- MDL Number:
- MFCD00064903
- MOL File:
- 131-28-2.mol
| Melting point | 138°; mp 176° |
|---|---|
| Boiling point | 555.14°C (rough estimate) |
| Density | 1.3285 (rough estimate) |
| refractive index | 1.5614 (estimate) |
| pka | pKb (20°) = 10.7, pKa = 9.3 |
| Water Solubility | 579.1mg/L(15 ºC) |
| CAS DataBase Reference | 131-28-2 |
| FDA UNII | CTT09X2F1M |
CI 15511 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 45067 | Narceine ≥98% | 131-28-2 | 1mg | $72 | 2026-04-30 | Buy |
| Cayman Chemical | 45067 | Narceine ≥98% | 131-28-2 | 5mg | $288 | 2026-04-30 | Buy |
| ChemScene | CS-0026319 | Narceine | 131-28-2 | 5mg | $135 | 2026-06-04 | Buy |
| ChemScene | CS-0026319 | Narceine | 131-28-2 | 10mg | $217 | 2026-06-04 | Buy |
| ChemScene | CS-0026319 | Narceine | 131-28-2 | 25mg | $433 | 2026-06-04 | Buy |
CI 15511 Chemical Properties,Uses,Production
Description
An alkaloid of opium (Papaver somniferum) was first isolated by Pelletier in 1832 but not characterized until some years later by Couerbe and Anderson, the latter assigning to it the formula C23H2909N which was accepted until Freund showed that it contains H20 of crystallization. The base remains in the mother liquors after removal of the major alkaloids. It forms slender, colourless needles or prisms of the trihydrate, m.p. 170°C. It is optically inactive and dissolves readily in alkalies forming metallic derivatives. It behaves as a weak, monoacidic base forming well-crystallized salts. The hydrochloride crystallizes with 5.5 H20 from cold, dilute HCI, or as the trihydrate from hot solutions. From MeOH it yields crystals with 1 mole of solvent, m.p. 190-2°C. The aurichloride forms reddish-yellow needles, m.p. 130°C and the picrate has m.p. 195°C. With chlorine water, followed by the addition of ammonia, it gives a characteristic blood-red colour while with dilute iodine solution, the solid alkaloid develops a blue colour. With ethyl nitrite, narceine forms an oximino derivative which, on exhaustive methylation, furnishes trimethylamine, hemipinic acid and 2-cyano-3- methoxy-4: s-methylenedioxy-1-vinylbenzene.
Uses
Narceine (Narcein), a quinolone derivative, is an opium alkaloid with anti-diabetic property[1][2].
Definition
ChEBI: Narceine is a stilbenoid.
Purification Methods
Recrystallise Narcein from water (as trihydrate). The styphnate has m 185-189o (from EtOH), and the picrate has m 200o (from EtOH). [Beilstein 19 H 370, 19 I 797, 19 II 386, 19 IV 4382.]
References
Couerbe., Annalen, 17,171 (1836)
Anderson., ibid, 86, 182 (1853)
Roser., ibid, 247, 167 (1888)
Freund, Frankforter., ibid, 277,20 (1893)
Freund, Oppenheimer., Ber., 42, 1084 (1909)
CI 15511 Preparation Products And Raw materials
Raw materials
Preparation Products
CI 15511 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Yisiyan Technology Research Center | 010-56645598 13366904824; | bjkaida@163.com | China | 1596 | 59 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Jinan Ruisi Pharmaceutical Technology Co., LTD | 0531-0531-69900633 19963472814 | changyuan20@163.com | China | 9937 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-025-66113011 15955137747 | cb5@aikonchem.com | China | 10354 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
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