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3-Thiophenemalonic acid

3-Thiophenemalonic acid structure

CAS No.: 21080-92-2

Chemical Name:: 3-Thiophenemalonic acid

Synonyms: 3-THIENYLMALONIC ACID;THIOPHENE-3-MALONIC ACID;2-(Thiophen-3-yl)Malonic acid;3-TMA;LK01-A;Ticarcillin EP Imp C;3-Thienylpropanedioic;Crude thiophenic acid;LABOTEST-BB LT00112328;Thiophen-3-malonic acid

CBNumber:: CB0446974

Molecular Formula:: C7H6O4S

Molecular Weight:: 186.19

MDL Number:: MFCD00005469

MOL File:: 21080-92-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-06-29 21:06:38

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3-Thiophenemalonic acid Properties

Melting point	139 °C (dec.) (lit.)
Boiling point	290.67°C (rough estimate)
Density	1.5439 (rough estimate)
refractive index	1.5500 (estimate)
storage temp.	2-8°C
form	powder to crystal
pka	2.73±0.10(Predicted)
color	White to Orange to Green
BRN	6503620
InChI	InChI=1S/C7H6O4S/c8-6(9)5(7(10)11)4-1-2-12-3-4/h1-3,5H,(H,8,9)(H,10,11)
InChIKey	GCOOGCQWQFRJEK-UHFFFAOYSA-N
SMILES	C(O)(=O)C(C1C=CSC=1)C(O)=O
CAS DataBase Reference	21080-92-2(CAS DataBase Reference)
FDA UNII	KK6MPZ6HAH
EPA Substance Registry System	Propanedioic acid, 3-thienyl- (21080-92-2)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

TSCA

TSCA listed

HS Code

29309090

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

REACH Registrations

Active

NFPA 704

	0
1		0

3-Thiophenemalonic acid price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	BP1080	Ticarcillin impurity C British Pharmacopoeia (BP) Reference Standard	21080-92-2	25MG	$266	2026-04-30	Buy
Sigma-Aldrich	215317	3-Thiophenemalonic acid 97%	21080-92-2	5g	$180	2023-06-20	Buy
TCI Chemical	T1354	3-Thiophenemalonic Acid >98.0%(HPLC)(T)	21080-92-2	5g	$22	2026-04-30	Buy
TCI Chemical	T1354	3-Thiophenemalonic Acid >98.0%(HPLC)(T)	21080-92-2	25g	$69	2026-04-30	Buy
Usbiological	426690	3-Thiophenemalonic Acid	21080-92-2	1g	$326	2026-06-03	Buy

Product number	Packaging	Price	Buy
BP1080	25MG	$266	Buy
215317	5g	$180	Buy
T1354	5g	$22	Buy
T1354	25g	$69	Buy
426690	1g	$326	Buy

3-Thiophenemalonic acid Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

3-Thiophenemalonic Acid (Ticarcillin EP Impurity C) is an intermediate used to synthesize temocillin. It is also used to prepare malonate-based inhibitors of mammalian serine racemase.

3-Thiophenemalonic acid synthesis

Synthesis of 3-Thiophenemalonic acid from 2-CYANO-3-THIENYL ACETATE

3-Thiophenemalonic acid Preparation Products And Raw materials

Raw materials

2-CYANO-3-THIENYL ACETATE diethyl (3-thienyl)malonate

Preparation Products

3-Thiophenemalonic acid Suppliers

Global( 315)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHUHAI HRD PHARMACEUTICAL CO., LTD.	7737188 13326687259	sales@hrdpharm.com	China	141	58
Chengda Pharmaceuticals Co., LTD.	0573-84601188-809	chl.wen@chengdapharm.com	China	174	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Beijing Donghualituo Techonlogy Development Co.,Ltd.	010-88425576	sales@dhltchem.com	China	793	59
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
TAIYUAN RHF CO.,LTD.	+86 351 7031519	sales@RHFChem.com	China	2334	56
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61

Supplier	Advantage
ZHUHAI HRD PHARMACEUTICAL CO., LTD.	58
Chengda Pharmaceuticals Co., LTD.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Beijing Donghualituo Techonlogy Development Co.,Ltd.	59
INTATRADE GmbH	66
TAIYUAN RHF CO.,LTD.	56
TCI (Shanghai) Development Co., Ltd.	81
Beijing HwrkChemical Technology Co., Ltd	55
Energy Chemical	61

View Lastest Price from 3-Thiophenemalonic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	3-Thiophenemalonic acid 21080-92-2	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
2026-06-30	3-Thiophenemalonic acid 21080-92-2		1kg	98%	1000kgs	Shaanxi Dideu New Materials Co. Ltd
2026-04-09	3-Thiophenemalonic acid 21080-92-2		1KG Ton	99%+	2 tons/month	ZHUHAI HRD PHARMACEUTICAL CO., LTD.

3-Thiophenemalonic acid
21080-92-2
$1.10
99.00%
Dideu Industries Group Limited

3-Thiophenemalonic acid
21080-92-2
$0.00
98%
Shaanxi Dideu New Materials Co. Ltd

3-Thiophenemalonic acid
21080-92-2
$0.00
99%+
ZHUHAI HRD PHARMACEUTICAL CO., LTD.

3-Thiophenemalonic acid Spectrum

3-Thiophenemalonic acid(21080-92-2)MS 3-Thiophenemalonic acid(21080-92-2)¹HNMR 3-Thiophenemalonic acid(21080-92-2)¹³CNMR 3-Thiophenemalonic acid(21080-92-2)IR1 3-Thiophenemalonic acid(21080-92-2)IR2

21080-92-2(3-Thiophenemalonic acid)Related Search:

Thiophene Folic acid Malonic acid Diisopropyl malonate Isopropylmalonic acid

Stearic acid Diethyl methylmalonate Dimethyl malonate Ethyl 2-(Chlorosulfonyl)acetate 3-Thiopheneacetic acid

Ticarcillin EP Impurity D Ticarcillin EP Impurity A Ticarcillin EP Impurity E Citric acid Diethyl malonate

Ascoric Acid Thiophene-3-ethanol 2-Methylpropanedioic acid

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LABOTEST-BB LT00112328 3-THIENYLMALONIC ACID 3-THIOPHENEMALONIC ACID 3-thienyl-propanedioicaci 3-Thienylpropanedioic acid 3-Thiophenemalonic acids 3-TMA Thiophen-3-malonic acid 3-ThienylpropanedioicAcid(3-Tma)C7H6O4S 3-Thiophenemalonic acid, 98+ % 3-Thienylpropanedioic 3-thienylpropanedioic acid (intermediate of ticarcillin & temocillin) (Thien-3-yl)malonic acid (Thien-3-yl)propanedioic acid 3-THIENYLPROPANEDIOIC ACID (3-TMA) The key intermediate of Ticarcillin & Temocillin α-Carboxythiophene-3-acetic acid α-Carboxythiophene-3-acetic acid, (3-Thienyl)malonic acid 2-(3-Thienyl)malonic acid 2-Thiophen-3-ylpropanedioic acid Propanedioic acid, 3-thienyl- Thiophen-3-ylmalonic acid 3-ThiopheneMalonic acid, 98+ % 5GR Ticarcillin SodiuM IMpurity C 2-(Thiophen-3-yl)Malonic acid Ticarcillin EP Impurity C 3-Thiophenemalonic acid 97% LK01-A Crude thiophenic acid Ticarcillin Impurity 3(Ticarcillin EP Impurity C) Ticarcillin EP Imp C Propanedioic acid, 2-(3-thienyl)- 3-Thiophenemalonic acid ISO 9001：2015 REACH 2-thiophen-3-ylpropanedioicaci Ticarcillin Impurity C(EP) 2-(thiophen-3-yl)propanedioic acid (3-thienylmalonic acid) 3-thienylmalonic acid (3-TMA) TicaRelated Compoundillin EP Impurity C THIOPHENE-3-MALONIC ACID 21080-92-2 21008-92-2 21080-92-1 C7H6O4S Reagents for Conducting Polymer Research Thiophene Derivatives (for Conduting Polymer Research) Sulphur Derivatives Pharmaceutical material and intermeidates Thiophene&Benzothiophene Organic acids Functional Materials Reagents for Conducting Polymer Research Thiophene Derivatives (for Conduting Polymer Research)