DESMETHYL LOPERAMIDE
- CAS No.
- 66164-07-6
- Chemical Name:
- DESMETHYL LOPERAMIDE
- Synonyms
- dLop;R 20905;DESMETHYL LOPERAMIDE;N-Desmethyl Loperamid;N-Desmethyl Loperamide;Desmethylloperamide D5;Desmethyl loperamide HCl;Loperamide-N-desmethyl 100 μg/mL in Acetonitrile;4-(4-Chlorophenyl)-4-hydroxy-N-methyl-a,a-diphenyl-1-piperidinebutanamide;4-(4-Chlorophenyl)-4-hydroxy-N-Methyl-α,α-diphenyl-1-piperidinebutanaMide
- CBNumber:
- CB0462831
- Molecular Formula:
- C28H31ClN2O2
- Molecular Weight:
- 463.01
- MDL Number:
- MFCD08063667
- MOL File:
- 66164-07-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| N-desmethyl Loperamide ≥98% | 16126 | 500μg | $203 |
| N-desmethyl Loperamide ≥98% | 16126 | 1mg | $363 |
| N-desmethyl Loperamide ≥98% | 16126 | 5mg | $1083 |
| N-Desmethyl-loperamide ≥98% | 16126 | 500μg | $184 |
| N-Desmethyl-loperamide ≥98% | 16126 | 1mg | $330 |
| More product size | |||
| Melting point | 219-221C |
|---|---|
| Boiling point | 678.3±55.0 °C(Predicted) |
| Density | 1+-.0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMF: 2 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 1 mg/ml |
| form | A crystalline solid |
| pka | 13.85±0.20(Predicted) |
| FDA UNII | 0R07BFN7L3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 | |||||||||
| HS Code | 9999999999 | |||||||||
| NFPA 704 |
|
DESMETHYL LOPERAMIDE price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16126 | N-desmethyl Loperamide ≥98% | 66164-07-6 | 500μg | $203 | 2026-04-30 | Buy |
| Cayman Chemical | 16126 | N-desmethyl Loperamide ≥98% | 66164-07-6 | 1mg | $363 | 2026-04-30 | Buy |
| Cayman Chemical | 16126 | N-desmethyl Loperamide ≥98% | 66164-07-6 | 5mg | $1083 | 2026-04-30 | Buy |
| Cayman Chemical | 16126 | N-Desmethyl-loperamide ≥98% | 66164-07-6 | 500μg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 16126 | N-Desmethyl-loperamide ≥98% | 66164-07-6 | 1mg | $330 | 2024-03-01 | Buy |
DESMETHYL LOPERAMIDE Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
A metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function
Uses
Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. N-Desmethyl-loperamide (dLop) is a major metabolite of loperamide. Like loperamide, dLop is a substrate of the ATP-dependent efflux transporter, P-glycoprotein. As a result, both the parent compound and the metabolite display restricted passage through the blood-brain barrier. dLop in biological samples can be analyzed by a variety of methods.
Definition
ChEBI: A monocarboxylic acid amide that is the methylamide of 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanoic acid.
DESMETHYL LOPERAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9539 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39039 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
View Lastest Price from DESMETHYL LOPERAMIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-21 | N-Desmethyl Loperamide
66164-07-6
|
$588.00-1260.00 | 99.73% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-12-25 | DESMETHYL LOPERAMIDE
66164-07-6
|
1gram | 99% | 10kg | Zhejiang J&C Biological Technology Co.,Limited |
-
- N-Desmethyl Loperamide
66164-07-6
- $588.00-1260.00
- 99.73%
- TargetMol Chemicals Inc.
-
- DESMETHYL LOPERAMIDE
66164-07-6
- $0.00
- 99%
- Zhejiang J&C Biological Technology Co.,Limited
