D-DOPA
- CAS No.
- 5796-17-8
- Chemical Name:
- D-DOPA
- Synonyms
- Levodopa Impurity D;3,4-DIHYDROXY-D-PHENYLALANINE;(R)-2-AMino-3-(3,4-dihydroxyphenyl)propanoic acid;D-DOPA;Dextrodopa;D-DOPA USP/EP/BP;3-Hydroxytyrosine;D-3-HYDROXYTYROSINE;3-HYDROXY-D-TYROSINE;H-D-TYR(3-HYDROXY)-OH
- CBNumber:
- CB0470294
- Molecular Formula:
- C9H11NO4
- Molecular Weight:
- 197.19
- MDL Number:
- MFCD00063061
- MOL File:
- 5796-17-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 276-278 °C(lit.) |
|---|---|
| alpha | D11 +13.0° (c = 5.27 in 1N HCl) |
| Boiling point | 448.4±45.0 °C(Predicted) |
| Density | 1.468±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | 0.5 M HCl: soluble |
| form | powder |
| pka | 2.24±0.20(Predicted) |
| color | white to tan |
| Merck | 13,3454 |
| BRN | 2417637 |
| Stability | Hygroscopic |
| InChI | InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m1/s1 |
| InChIKey | WTDRDQBEARUVNC-ZCFIWIBFSA-N |
| SMILES | C(O)(=O)[C@@H](CC1=CC=C(O)C(O)=C1)N |
| CAS DataBase Reference | 5796-17-8(CAS DataBase Reference) |
| FDA UNII | 8T862R29FY |
| UNSPSC Code | 12352209 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H335-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-23 | |||||||||
| HS Code | 2922500090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
D-DOPA price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D9378 | 3,4-Dihydroxy-D-phenylalanine powder, ≥95% | 5796-17-8 | 250mg | $279 | 2026-04-30 | Buy |
| Sigma-Aldrich | D9378 | 3,4-Dihydroxy-D-phenylalanine powder, ≥95% | 5796-17-8 | 1g | $803 | 2026-04-30 | Buy |
| Cayman Chemical | 13249 | D-DOPA ≥95% | 5796-17-8 | 50mg | $63 | 2026-04-30 | Buy |
| Cayman Chemical | 13249 | D-DOPA ≥95% | 5796-17-8 | 100mg | $118 | 2026-04-30 | Buy |
| Cayman Chemical | 13249 | D-DOPA ≥95% | 5796-17-8 | 250mg | $242 | 2026-04-30 | Buy |
D-DOPA Chemical Properties,Uses,Production
Chemical Properties
Tan Solid
Uses
A DOPA enantiomer that lacks biological activity.
Uses
D-DOPA (Levodopa EP Impurity D) is a DOPA enantiomer that lacks biological activity.
Definition
ChEBI: The D-enantiomer of dopa.
Biochem/physiol Actions
DOPA enantiomer that lacks biological activity.
Purification Methods
Likely impurities are vanillin, hippuric acid, 3-methoxytyrosine and 3-aminotyrosine. DOPA recrystallises from large volumes of H2O forming colourless white needles; its solubility in H2O is 0.165%, but it is insoluble in EtOH, *C6H6, CHCl3, and EtOAc. Also crystallise it by dissolving it in dilute HCl and adding dilute ammonia to give pH 5, under N2. Alternatively, crystallise it from dilute aqueous EtOH. It is rapidly oxidised in air when moist, and darkens, particularly in alkaline solution. Dry it in vacuo at 70o in the dark, and store it in a dark container preferably under N2. It has at 220.5nm (log 3.79) and 280nm (log 3.42) in 0.001N max HCl. [Yamada et al. Chem Pharm Bull Jpn 10 693 1962, Bretschneider et al. Helv Chim Acta 56 2857 1973, NMR: Jardetzky & Jardetzky J Biol Chem 233 383 1958, Beilstein 4 IV 2492, 2493.]
D-DOPA Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Junye Biopharmaceutical Technology Co., Ltd | 0512-0512-53662086-8001 18913766772 | wangli@jyk-biotech.cn | China | 490 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
View Lastest Price from D-DOPA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-27 | D-DOPA
5796-17-8
|
$198.00-797.00 | 10g | TargetMol Chemicals Inc. | |||
![]() |
2026-03-20 | D-DOPA
5796-17-8
|
$9.90 | 100KG | 99% | 10 tons | Hebei Chuanghai Biotechnology Co., Ltd | |
![]() |
2021-08-12 | D-DOPA
5796-17-8
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
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