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ChemicalBook >> CAS DataBase List >>N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide

N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide

N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide Structure
N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide structure
CAS No.
1126366-36-6
Chemical Name:
N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide
Synonyms
AZD8542;AZD-8542;AZD 8542;Benzamide, N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)-;N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide
CBNumber:
CB04772972
Molecular Formula:
C25H24N4O2
Molecular Weight:
412.48
MDL Number:
MOL File:
1126366-36-6.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
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N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide Properties

Boiling point 572.5±50.0 °C(Predicted)
Density 1.18±0.1 g/cm3(Predicted)
pka 13.32±0.70(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS07,GHS08
Signal word  Danger
Hazard statements  H360-H302
Precautionary statements  P264-P270-P301+P312-P330-P501

N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0078180 AZD8542 99.49% 1126366-36-6 1mg $361 2026-06-04 Buy
ChemScene CS-0078180 AZD8542 99.49% 1126366-36-6 5mg $845 2026-06-04 Buy
ChemScene CS-0078180 AZD8542 99.49% 1126366-36-6 10mg $1192 2026-06-04 Buy
ChemScene CS-0078180 AZD8542 99.49% 1126366-36-6 25mg $1809 2026-06-04 Buy
ChemScene CS-0078180 AZD8542 99.49% 1126366-36-6 50mg $2362 2026-06-04 Buy
Product number Packaging Price Buy
CS-0078180 1mg $361 Buy
CS-0078180 5mg $845 Buy
CS-0078180 10mg $1192 Buy
CS-0078180 25mg $1809 Buy
CS-0078180 50mg $2362 Buy

N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide Chemical Properties,Uses,Production

Description

AZD8542 is an antagonist of Smoothened (SMO), with potential as an oncology therapeutic. It is a novel Hedgehog (Hh) pathway antagonist on tumor progression with an emphasis on the role of the stroma compartment.

Uses

AZD8542 is an antagonist of Smoothened (SMO), playing an important role in oncology. AZD8542 is a Hedgehog (Hh) pathway antagonist on tumor progression with an emphasis on the role of the stroma compartment[1][2].

References

[1] Rosa F. Hwang, INHIBITION OF THE HEDGEHOG PATHWAY TARGETS THE TUMOR-ASSOCIATED STROMA IN PANCREATIC CANCER. Mol Cancer Res. 2012 Sep; 10(9): 1147–1157.
[2] Dakin Leslie, et al. Preparation of amide compounds containing heterocycle moiety as hedgehog pathway inhibitors. World Intellectual Property Organization, WO2009027746 A1

N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4861 55
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
Shenzhen Botel Biotechnology Co. Ltd. 13316949107 13316968096 1979313431@qq.com China 9618 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Changzhou Chenhong Biotechnology Co., Ltd. +86-0519-85788828 +86-13775037613 sales@chemrenpharm.com China 4058 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4565 58
Wuhan Topule +86-02787215551 19945035818 2936752263@qq.com China 7985 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2223443625@qq.com China 7996 58
Wuhan Augda Biotechnology Co., Ltd 15071299552 262933239@qq.com China 7200 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Supplier Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai Beckham Medical Technology Co., Ltd 55
Shenzhen Botel Biotechnology Co. Ltd. 58
TargetMol Chemicals Inc. 58
Changzhou Chenhong Biotechnology Co., Ltd. 58
ShangHai ChuanQian Chemcial Technique Centre 58
Wuhan Topule 58
Hubei Kele Fine Chemical Co., Ltd 58
Wuhan Augda Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58

View Lastest Price from N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AZD8542 pictures 2026-07-27 AZD8542
1126366-36-6
 $163.00-535.00 99.96% 10g TargetMol Chemicals Inc.
  • AZD8542 pictures
  • AZD8542
    1126366-36-6
  • $163.00-535.00
  • 99.96%
  • TargetMol Chemicals Inc.

N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide Spectrum

N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide(1126366-36-6)1HNMR

1126366-36-6(N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide)Related Search:

N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide Benzamide, N-[5-(1H-imidazol-2-yl)-2-methylphenyl]-4-(2-pyridinylmethoxy)-, hydrochloride (1:2) Hedgehog IN-2 N-[5-(1H-imidazol-2-yl)-2,4-dimethylphenyl]-4-[(pyridin-2-yl)methoxy]benzamide AZ 12080282 Dihydrochloride
Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)-

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N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide AZD 8542 AZD-8542 Benzamide, N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)- AZD8542 1126366-36-6