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2-Amino-5-nitropyrimidine

2-Amino-5-nitropyrimidine Structure
2-Amino-5-nitropyrimidine structure
CAS No.
3073-77-6
Chemical Name:
2-Amino-5-nitropyrimidine
Synonyms
5-nitropyrimidin-2-amine;Enheptin P;TIMTEC-BB SBB004166;2-AMINO-5-NITROPRIDINE;5-Nitro-2-pyrimidinamine;5-Nitro-2-aminopyrimidine;2-AMINO-5-NITROPYRIMIDINE;2-Pyrimidinamine, 5-nitro-;5-nitropyrimidin-2-ylamine;5-Nitropyrimidine-2(1H)-imine
CBNumber:
CB0495790
Molecular Formula:
C4H4N4O2
Molecular Weight:
140.1
MDL Number:
MFCD00006103
MOL File:
3073-77-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 22:50:20
Request For Quotation

2-Amino-5-nitropyrimidine Properties

Melting point 235-237 °C(lit.)
Boiling point 256.57°C (rough estimate)
Density 1.5799 (rough estimate)
refractive index 1.8010 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Dimethylformamide
form Fine Crystalline Powder
pka 0.04±0.10(Predicted)
color Light yellow
InChI 1S/C4H4N4O2/c5-4-6-1-3(2-7-4)8(9)10/h1-2H,(H2,5,6,7)
InChIKey SSHFCFRJYJIJDV-UHFFFAOYSA-N
SMILES Nc1ncc(cn1)[N+]([O-])=O
CAS DataBase Reference 3073-77-6(CAS DataBase Reference)
NIST Chemistry Reference 2-Amino-5-nitropyrimidine(3073-77-6)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P280a-P304+P340-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-37/39-36
WGK Germany  3
HazardClass  IRRITANT
HS Code  29335990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
0 0

2-Amino-5-nitropyrimidine price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A70836 2-Amino-5-nitropyrimidine 98% 3073-77-6 1g $34 2023-06-20 Buy
TCI Chemical A2031 2-Amino-5-nitropyrimidine >98.0%(GC) 3073-77-6 1g $88 2026-04-30 Buy
Usbiological A1379-19 2-Amino-5-nitropyrimidine 5g $403 2026-06-03 Buy
Usbiological 260144 2-Amino-5-nitropyrimidine Asreported 3073-77-6 2g $352 2026-06-03 Buy
Usbiological 260144 2-Amino-5-nitropyrimidine Asreported 3073-77-6 5g $542 2026-06-03 Buy
Product number Packaging Price Buy
A70836 1g $34 Buy
A2031 1g $88 Buy
A1379-19 5g $403 Buy
260144 2g $352 Buy
260144 5g $542 Buy

2-Amino-5-nitropyrimidine Chemical Properties, Uses, Production

Synthesis

Step 1: Add sodium nitromalondialdehyde monohydrate (2) (13.0 g, 0.1 mol) in H2O (100 mL) to a solution of 5-aminotetrazole monohydrate (10.9 g, 0.1 mol) in 2 N HCl (70 mL). Stir the reaction mixture for 30 minutes. Filter out the precipitated solid, wash with water and air dry. Volume 11.7 g (63%), yellow powder. Melting point 125-130°C (decomposes).

Step 2: Reflux a solution of compound 4 (7.70 g, 42 mmol) in PhMe (50 mL) for 30 minutes using a Dean-Stark trap. Evaporate the solvent under reduced pressure; the oily product crystallizes upon cooling, suitable for further synthesis without purification. Yield 6.25 g (90%), pale yellow crystals. Melting point 56-58°C.

Analytical grade azide 6 was obtained by sublimation of the crude product at 130–150°C (5 mm Hg). Step 3: Azide 6 (0.083 g, 0.5 mmol) was dissolved in MeCN (3 ml), and ammonia was allowed to flow through the solution for 5 minutes. The reaction mixture was kept at room temperature overnight. The precipitated solid was filtered off and then recrystallized from water. Yield: 0.043 g (61%), colorless crystals, 2-amino-5-nitropyrimidine.

Application

2-Amino-5-nitropyrimidine was first discovered in extremophilic bacteria. As a compatible solute that regulates cellular osmotic pressure, it helps microorganisms adapt to harsh environments such as high salt content. Therefore, 2-amino-5-nitropyrimidine shows broad commercial application prospects in many fields such as bioprotection, biomedicine, and biotechnology.

Chemical Properties

light yellow fine crystalline powder

2-Amino-5-nitropyrimidine Preparation Products And Raw materials

Raw materials

Ethanol Piperidine Pentane Sodium nitrite Guanidine hydrochloride
Mucobromic acid 2-methoxy-5-nitropyrimidine Pyrimidine, 5-nitro- (8CI,9CI) O-Methylisourea hydrochloride

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Preparation Products

2-Amino-5-nitropyrimidine Suppliers

Global Suppliers ( 290)
Supplier Tel Email Country ProdList Advantage
Shanghai jing Hao pharmaceutical technology co., LTD 021-68900963 15618693615 sales@jinghaopharma.com China 300 58
Nanbu County Chengxin Technology Co., Ltd. 0838-5675166 15883665058 nbcxkj@126.com China 956 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 94607 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
New Energy Chemicals 0515-82159099 13770142076 info@njuchem.com China 251 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Supplier Advantage
Shanghai jing Hao pharmaceutical technology co., LTD 58
Nanbu County Chengxin Technology Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
3B Pharmachem (Wuhan) International Co.,Ltd. 69
New Energy Chemicals 65
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56

View Latest Price from 2-Amino-5-nitropyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-5-nitropyrimidine pictures 2024-07-18 2-Amino-5-nitropyrimidine
3073-77-6
 $1.00 1Kg 98% 20T Shaanxi Dideu Medichem Co. Ltd
2-Amino-5-nitropyrimidine pictures 2021-08-12 2-Amino-5-nitropyrimidine
3073-77-6
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-Amino-5-nitropyrimidine pictures 2019-07-06 2-Amino-5-nitropyrimidine
3073-77-6
 $8.00 1kg 99% 10MT Career Henan Chemical Co

2-Amino-5-nitropyrimidine Spectrum

2-Amino-5-nitropyrimidine(3073-77-6)MS2-Amino-5-nitropyrimidine(3073-77-6)1HNMR2-Amino-5-nitropyrimidine(3073-77-6)13CNMR2-Amino-5-nitropyrimidine(3073-77-6)IR12-Amino-5-nitropyrimidine(3073-77-6)IR22-Amino-5-nitropyrimidine(3073-77-6)Raman

3073-77-6 (2-Amino-5-nitropyrimidine) Related Search:

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2-AMINO-5-NITROPYRIMIDINE TIMTEC-BB SBB004166 2-Pyrimidinamine, 5-nitro- 5-Nitro-2-pyrimidinamine 5-nitropyrimidin-2-ylamine 2-Amino-5-nitropyrimidine, 97+% 2-Pyrimidinamine, 5-nitro- (9CI) 2-AMINO-5-NITROPRIDINE 5-Nitro-2-aminopyrimidine Enheptin P 2-Amino-5-nitropyrimidine ,98% 5-Nitropyrimidine-2(1H)-imine 2-AMINO-5-NITROPYRIMIDINE 97% 5-nitropyrimidin-2-amine(SALTDATA: FREE) 5-Nitropyrimidin-2-amine, 2-Amino-5-nitro-1,3-diazine 2-Amino-5-nitropyrimidine > 2-Amino-5-nitropyrimidine ISO 9001：2015 REACH 5-nitropyrimidin-2-amine 3073-77-6 C4H4N4O2 Pyrimidines Heterocyclic Building Blocks Building Blocks Heterocycle-Pyrimidine series Pyrimidines Building Blocks Heterocyclic Building Blocks Pyridines, Pyrimidines, Purines and Pteredines PYRIMIDINE