Leoidin(SH)
- CAS No.
- 105350-54-7
- Chemical Name:
- Leoidin(SH)
- Synonyms
- LEOIDIN(AS);Leoidin(SH);11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2,4-dichloro-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-, methyl ester
- CBNumber:
- CB0506986
- Molecular Formula:
- C18H14Cl2O7
- Molecular Weight:
- 413.208
- MDL Number:
- MFCD07779122
- MOL File:
- 105350-54-7.mol
- MSDS File:
- SDS
Leoidin(SH) price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29939 | Leoidin ≥95% | 105350-54-7 | 1mg | $174 | 2026-04-30 | Buy |
| Cayman Chemical | 29939 | Leoidin ≥95% | 105350-54-7 | 5mg | $648 | 2026-04-30 | Buy |
| Biosynth | FEA35054 | Leoidin | 105350-54-7 | 5mg | $1067.3 | 2026-06-04 | Buy |
| Biosynth | FEA35054 | Leoidin | 105350-54-7 | 10mg | $1484.9 | 2026-06-04 | Buy |
| Biosynth | FEA35054 | Leoidin | 105350-54-7 | 25mg | $2784.25 | 2026-06-04 | Buy |
Leoidin(SH) Chemical Properties,Uses,Production
Uses
Leoidin is an OATP1B1 and OATP1B3 inhibitor with Ki values of 0.08 and 1.84 μM，respectively. Leoidin inhibits sodium fluorescein uptake in CHO cells expressing the human OATP1B1 and OATP1B3. Leoidin is an antibacterial agent against both Gram-positive and Gram-negative pathogens. Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) (IC50= 42 μM) and inhibits protein synthesis in bacterial. Leoidin can be isolated from L. gangaleoides[1][2].
Definition
ChEBI: 8,10-dichloro-3,9-dihydroxy-1,4,7-trimethyl-6-oxo-2-benzo[b][1,4]benzodioxepincarboxylic acid methyl ester is a carbonyl compound.
References
[1] De Bruyn T, et al. Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol. 2013 Jun;83(6):1257-67. DOI:10.1124/mol.112.084152
[2] Hu Y, et al. Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4820-9. DOI:10.1128/AAC.00800-16
Leoidin(SH) Preparation Products And Raw materials
Raw materials
Preparation Products
Leoidin(SH) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8857 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Saikerui Biotechnology Co. , Ltd. | 021-58000709 13120558703 | sales@scrbio.com | China | 9873 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 11975 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | rose.shi@synzest.com | China | 6204 | 58 |
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