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BB-F-Yne

BB-F-Yne structure

CAS No.: 2219331-30-1

Chemical Name:: BB-F-Yne

Synonyms: BB-F-Yne;BBFYne,BB F Yne;[1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-fluoro-1-iminoethyl)amino]butyl]-4'-ethynyl-

CBNumber:: CB06197328

Molecular Formula:: C28H26FN5O

Molecular Weight:: 467.54

MDL Number:

MOL File:: 2219331-30-1.mol

MSDS File:: SDS

Last updated:2025-04-18 09:51:33

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BB-F-Yne Properties

Density	1.21±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 5 mg/mL; DMF:PBS (pH 7.2) (1:5): 0.16 mg/mL; DMSO: 20 mg/mL
form	A crystalline solid
pka	11.43±0.10(Predicted)

BB-F-Yne price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	25379	BB-F-Yne ≥98%	2219331-30-1	500μg	$121	2026-04-30	Buy
Cayman Chemical	25379	BB-F-Yne ≥98%	2219331-30-1	1mg	$193	2026-04-30	Buy
Cayman Chemical	25379	BB-F-Yne ≥98%	2219331-30-1	5mg	$667	2026-04-30	Buy
ChemScene	CS-0136693	BB-F-Yne	2219331-30-1	500??g	$352	2026-06-04	Buy
ChemScene	CS-0136693	BB-F-Yne	2219331-30-1	1mg	$563	2026-06-04	Buy

Product number	Packaging	Price	Buy
25379	500μg	$121	Buy
25379	1mg	$193	Buy
25379	5mg	$667	Buy
CS-0136693	500??g	$352	Buy
CS-0136693	1mg	$563	Buy

BB-F-Yne Chemical Properties, Uses, Production

Description

BB-F-Yne is a cell-permeable derivative of the protein arginine diminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-F-Yne inhibits PAD1-4 and has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.

Uses

BB-F-Yne is a protein arginine deiminase (PAD) inhibitor with Ki values of PAD1-4.are 2050, 1700, 1100, 3100 M-1min-1 respectively. BB-F-Yne can be used as a click probe to label PAD[1].

References

[1] Nemmara VV, et al. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). ACS Chem Biol. 2018 Mar 16;13(3):712-722. DOI:10.1021/acschembio.7b00957

BB-F-Yne Preparation Products And Raw materials

Raw materials

Preparation Products

BB-F-Yne Suppliers

Global Suppliers ( 7)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774 400-920-5774	sales@glpbio.cn	China	6705	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11123	58
Beijing Biocreative Technology Co., Ltd.	15522676233	3007606172@qq.com	China	1246	58

Supplier	Advantage
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Beijing Biocreative Technology Co., Ltd.	58

2219331-30-1 (BB-F-Yne) Related Search:

BB-F-Yne [1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-, hydrochloride (1:1) NA BB-Cl-Amidine BB-Cl-Yne

F-Amidine (trifluoroacetate salt)

1of2

BB-F-Yne BBFYne,BB F Yne [1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-fluoro-1-iminoethyl)amino]butyl]-4'-ethynyl- 2219331-30-1