7-Bromo-3-hydroxy-naphthalene-2-carboxylic acid
- CAS No.
- 1779-11-9
- Chemical Name:
- 7-Bromo-3-hydroxy-naphthalene-2-carboxylic acid
- Synonyms
- 7-bromo-3-hydroxy-2-naphthoic acid;2-amino-1-(6-bromophenyl)ethanol;3-Hydroxy-7-bromo-2-naphthoic acid;6-Bromo-2-naphthol-3-carboxylic Acid;7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBO;7-Bromo-3-hydroxy-2-naphthoic Acid >3-Isoxazolecarboxylicacid,5-(7-furanyl)-;7-bromo-3-hydroxy-2-naphthalenecarboxylicaci;7-bromo-3-hydroxynaphthalene-2-carboxylicaci;7-Bromo-3-hydroxy-2-naphthalenecarboxylic acid
- CBNumber:
- CB0679806
- Molecular Formula:
- C11H7BrO3
- Molecular Weight:
- 267.08
- MDL Number:
- MFCD00137823
- MOL File:
- 1779-11-9.mol
- MSDS File:
- SDS
| Melting point | 262 °C |
|---|---|
| Boiling point | 420.3±35.0 °C(Predicted) |
| Density | 1.772±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 2.81±0.30(Predicted) |
| form | powder to crystal |
| color | White to Yellow |
| BRN | 2372925 |
| InChIKey | XZWXQSGFZHRDNB-UHFFFAOYSA-N |
| CAS DataBase Reference | 1779-11-9 |
| EPA Substance Registry System | 2-Naphthalenecarboxylic acid, 7-bromo-3-hydroxy- (1779-11-9) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29181990 | |||||||||
| NFPA 704 |
|
7-Bromo-3-hydroxy-naphthalene-2-carboxylic acid price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 73178 | 7-Bromo-3-hydroxy-2-naphthoic acid ≥98.0% (HPLC), 98.0-102.0 wt. % (AT) | 1779-11-9 | 5g | $107 | 2026-04-30 | Buy |
| Sigma-Aldrich | 73178 | 7-Bromo-3-hydroxy-2-naphthoic acid ≥98.0% (HPLC), 98.0-102.0 wt. % (AT) | 1779-11-9 | 50g | $346 | 2026-04-30 | Buy |
| TCI Chemical | B3180 | 7-Bromo-3-hydroxy-2-naphthoic Acid >98.0%(GC)(T) | 1779-11-9 | 1g | $31 | 2026-04-30 | Buy |
| TCI Chemical | B3180 | 7-Bromo-3-hydroxy-2-naphthoic Acid >98.0%(GC)(T) | 1779-11-9 | 5g | $72 | 2026-04-30 | Buy |
| AstaTech | 56883 | 7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID 97% | 1779-11-9 | 1G | $10 | 2026-04-30 | Buy |
7-Bromo-3-hydroxy-naphthalene-2-carboxylic acid Chemical Properties, Uses, Production
Chemical Properties
Yellow solid
Synthesis Reference(s)
Journal of Medicinal Chemistry, 33, p. 171, 1990 DOI: 10.1021/jm00163a029
Synthesis
1779-10-8
1779-11-9
The general procedure for the synthesis of 3-hydroxy-7-bromo-2-naphthalenecarboxylic acid from 1,6-dibromo-2-hydroxynaphthalene-3-carboxylic acid was as follows: in a 1L three-necked flask, 40 g of 4,7-dibromo-3-hydroxy-2-naphthalenecarboxylic acid (0.116 mol) and 500 ml of glacial acetic acid were added, and the mixture was stirred thoroughly until uniform. Subsequently, 18 g of tin powder (0.153 mol) and 130 ml of concentrated hydrochloric acid were sequentially added to the reaction mixture. The reaction mixture was heated to 125°C and the reaction was refluxed at this temperature for 12 hours. After completion of the reaction, 300 ml of water was added to the mixture and cooled to room temperature with stirring. The reaction mixture was filtered and the filter cake was washed twice with 200 ml of water. Finally, the filter cake was dried in an oven to give 29.9 g of the target product 3-hydroxy-7-bromo-2-naphthalenecarboxylic acid in 96.5% yield.
References
[1] Patent: EP2573067, 2013, A1. Location in patent: Paragraph 0053; 0054
[2] Patent: CN106866433, 2017, A. Location in patent: Paragraph 0078; 0079; 0080
[3] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 1021
[4] Proceedings - Indian Academy of Sciences, Section A, 1950, vol. 32, p. 292,298
[5] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 19, p. 790
7-Bromo-3-hydroxy-naphthalene-2-carboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 45000 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Changzhou Huanling Chemical Co., Ltd. | 89803005 18206112582 | info@huanlingchem.com | China | 983 | 68 |
| Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. | 21-57721279 18121011378 | sales@shydchem.com.cn | China | 998 | 56 |
| Accela ChemBio Co.,Ltd. | 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Paulshine Chemical Co., Ltd. | +86-021-37788663 | China | 186 | 64 |
View Latest Price from 7-Bromo-3-hydroxy-naphthalene-2-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | 7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID
1779-11-9
|
$6.68 | 1KG | 97%-99% | 1kg-1000kg | Career Henan Chemical Co |
-
- 7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID
1779-11-9
- $6.68
- 97%-99%
- Career Henan Chemical Co
