D-chiro-inositol
- CAS No.
- 643-12-9
- Chemical Name:
- D-chiro-inositol
- Synonyms
- D-CHIRO-INOSITOL;D-Inositol;chiro-Inositol;1D-CHIRO-INOSITOL;L-(−D-chiro-inosito1;D - Chiral inositol;D-chiro-Inositol,95%;D-(+)-CHIRO-INOSITOL;1D-chiro-Inositol>
- CBNumber:
- CB0718693
- Molecular Formula:
- C6H12O6
- Molecular Weight:
- 180.16
- MDL Number:
- MFCD00272608
- MOL File:
- 643-12-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 230 °C |
|---|---|
| Boiling point | 232.96°C (rough estimate) |
| Density | 1.2805 (rough estimate) |
| refractive index | 1.5730 (estimate) |
| storage temp. | 2-8°C |
| solubility | Water |
| pka | 12.63±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| optical activity | [α]23/D +60°, c = 1.2 in H2O |
| Water Solubility | 403.4g/L(11 ºC) |
| InChI | InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3-,4-,5+,6+/m0/s1 |
| InChIKey | CDAISMWEOUEBRE-LKPKBOIGSA-N |
| SMILES | O[C@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O |
| CAS DataBase Reference | 643-12-9(CAS DataBase Reference) |
| FDA UNII | 6R79WV4R10 |
| UNSPSC Code | 12352201 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 24/25-36-26 |
| WGK Germany | 3 |
| HS Code | 29061390 |
| Storage Class | 11 - Combustible Solids |
D-chiro-inositol price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 468045 | D-(+)-chiro-Inositol 95% | 643-12-9 | 100mg | $161 | 2026-04-30 | Buy |
| Sigma-Aldrich | 468045 | D-(+)-chiro-Inositol 95% | 643-12-9 | 1g | $344 | 2026-04-30 | Buy |
| TRC | TRC-I666055-500MG | D-chiro-inositol >95%(HPLC) | 643-12-9 | 500mg | $153 | 2026-06-03 | Buy |
| TRC | TRC-I666055-1G | D-chiro-inositol >95%(HPLC) | 643-12-9 | 1g | $195 | 2026-06-03 | Buy |
| TRC | TRC-I666055-100MG | D-chiro-inositol >95%(HPLC) | 643-12-9 | 100mg | $95 | 2026-06-03 | Buy |
D-chiro-inositol Chemical Properties, Uses, Production
Preparation
D-chiro-inositol, in its pure form, is a white powder, slightly sweet, and readily soluble in water. Currently, the main method for industrial-scale production is natural extraction. D-chiro-inositol exists in nature as compounds in plants such as legumes and buckwheat, as well as insects (see Table 1). Its precursor, pinol, is also found in various plants, such as bougainvillea, sugar pine, and red sandalwood. Chemical synthesis of chiral inositol has not yet achieved a breakthrough, as the process is cumbersome and costly. Genetic engineering production of D-chiro-inositol involves genetically modifying Bacillus subtilis to convert muscle inositol into D-chiro-inositol; however, this method currently suffers from low bioconversion rates and high costs. The antibiotic kasugamycin, as a precursor of D-chiro-inositol, can be purified after acetylation, representing another production route.
Chemical Properties
Off-White Powder
Uses
The inositols and their phosphates have been used in the development of metabolically stable insulin mediators, inhibitors, and modulators of important metabolic functions such as glycolysis. Inositols are stable to degradative enzymes in vivo because they lack a hydrolytically labile glycosidic linkage.
Definition
ChEBI: Myo-inositol is an inositol having myo- configuration. It has a role as a member of compatible osmolytes, a nutrient, an EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor, a human metabolite, a Daphnia magna metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite.
Biochem/physiol Actions
Important second messenger in insulin signal transduction.
D-chiro-inositol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Varror Biotech Co., Ltd. | 15817492830;18689229217 15817492830 | sales@varror.com | China | 50 | 58 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 | sales@uhnshanghai.com | China | 1983 | 58 |
| Shaanxi Pioneer Biotech Co.,Ltd. | 029-84385017-8011 15202491660 | sales8@pioneerbiotech.com | China | 449 | 58 |
| Shanxi Bethlehem Pharm-Tech Co.,Ltd. | 19135651983 19135651206 | 243332738@qq.com | China | 959 | 58 |
| Hubei jian chu biological technology co., LTD | 027-65528353 13554206703 | HBJC3279834739@foxmail.com | China | 1000 | 58 |
| Hunan Xinbelai Biotechnology Co., LTD | 18667946270 18667946270 | wangzeren1@synbiolab.cn | China | 114 | 58 |
| Wuxi Jingyao Bio-Technology Co., Ltd. | 88770633 13961738808 | jingyaobiotech@126.com | China | 389 | 55 |
| Nanjing Yiming Pharmaceutical Technology Co., Ltd. | 19850700912; 19850700912 | 13851286085@163.com | China | 979 | 58 |
| Shenzhen Hyra Biotech Co., Ltd | 0755-27208059 15115151094 | sylvia@hygieia.com.cn | China | 56 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
Related articles
- Inositol, myo-inositol & D-chiro-inositol
- Inositol can be found in nine forms. Myo-inositol and D-chiro-inositol are most common in supplements.
- Nov 22,2023
View Latest Price from D-chiro-inositol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | D-(+)-CHIRO-INOSITOL
643-12-9
|
$28.00-400.00 | 25g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
 |
2026-09-15 | D-(+)-CHIRO-INOSITOL
643-12-9
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-09-15 | D-chiro-inositol
643-12-9
|
$300.00-500.00 | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD |
-
- D-(+)-CHIRO-INOSITOL
643-12-9
- $28.00-400.00
- 0.98
- Shanghai UCHEM Inc.
-
- D-(+)-CHIRO-INOSITOL
643-12-9
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- D-chiro-inositol
643-12-9
- $300.00-500.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
643-12-9 (D-chiro-inositol ) Related Search:
1of4
