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4-Aminoantipyrine hydrochloride

CAS No.
22198-72-7
Chemical Name:
4-Aminoantipyrine hydrochloride
Synonyms
4-AA HCl;Ampyrone HCl;4-AMINOANTIPYRINE HCL;AMPYRONE HYDROCHLORIDE;Aminoantipyrine Hydrochloride;4-AMINOPHENAZONE HYDROCHLORIDE;4-Aminoantipyrine hydrochloride;4-AMINOANTIPYRINE HYDROCHLORIDE 99%;4-Aminoantipyrine hydrochloride,99%;4-Aminoantipyrine Hydrochloride 
CBNumber:
CB0726324
Molecular Formula:
C11H14ClN3O
Molecular Weight:
239.7
MDL Number:
MFCD00042012
MOL File:
22198-72-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:48:28

4-Aminoantipyrine hydrochloride Properties

Melting point 220-225 °C
storage temp. Storage temp. 2-8°C
form powder to crystal
color White to Light yellow to Light orange
Water Solubility almost transparency
CAS DataBase Reference 22198-72-7(CAS DataBase Reference)
FDA UNII F7WGH82I6D
EPA Substance Registry System 3H-Pyrazol-3-one, 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-, monohydrochloride (22198-72-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501
Hazard Codes  Xn
Risk Statements  36/37/38-22
Safety Statements  36/37/39-26
TSCA  TSCA listed
HS Code  2933.11.0000
NFPA 704
0
1 0

4-Aminoantipyrine hydrochloride price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A0257 4-Aminoantipyrine Hydrochloride [for Biochemical Research] >98.0%(HPLC)(T) 22198-72-7 5g $35 2026-04-30 Buy
TCI Chemical A0257 4-Aminoantipyrine Hydrochloride [for Biochemical Research] >98.0%(HPLC)(T) 22198-72-7 25g $90 2026-04-30 Buy
ChemScene CS-0153632 4-Amino-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one hydrochloride ≥95% 22198-72-7 25g $81 2026-06-04 Buy
Chem-Impex 39280 4-Aminoantipyrine hydrochloride [for Biochemical Research] ≥98%(Assaybytitration,HPLC) 22198-72-7 5G $61.19 2026-05-19 Buy
Chem-Impex 39280 4-Aminoantipyrine hydrochloride [for Biochemical Research] ≥98%(Assaybytitration,HPLC) 22198-72-7 25G $185.18 2026-05-19 Buy
Product number Packaging Price Buy
A0257 5g $35 Buy
A0257 25g $90 Buy
CS-0153632 25g $81 Buy
39280 5G $61.19 Buy
39280 25G $185.18 Buy

4-Aminoantipyrine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

faint yellow to orange crystalline powder

Uses

4-Aminoantipyrine (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

Method for synthesizing free base:
1) Prepare a solution of antipyrine with 50% sulfuric acid.
2)Flow the solution and sodium nitrite solution into the nitrosation reactor at the same time, control the flow rate of both, control the reaction temperature 45-50, react under stirring, and measure the reaction endpoint with iodine powder starch test paper to adjust the water flow rate.
3) The nitrosative antipyrine generated by nitrosation immediately flows into the reduction tank and reacts with the aqueous solution of reductant prepared in the tank.
4) Take a sample to measure the pH value, the pH value between 5.4-5.8 when the reduction is over, adjust the pH value to 5.8-6.0, raise the temperature to 100 , hydrolyze for 3h, lower the temperature to 80 , neutralize with liquid ammonia to pH 7-7.5, and leave it to stratify.
5) Separate the waste water to get 4-aminoantipyrine oil, which is pressed into a crystallization tank, stirred, cooled crystallized and filtered to get 4-aminoantipyrine.

4-Aminoantipyrine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

4-Aminoantipyrine hydrochloride Suppliers

Global( 98)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853 ivy@hnhbsj.com China 7236 62
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75

View Lastest Price from 4-Aminoantipyrine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-AMINOANTIPYRINE HYDROCHLORIDE pictures 2026-07-02 4-AMINOANTIPYRINE HYDROCHLORIDE
22198-72-7
1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
4-AMINOANTIPYRINE HYDROCHLORIDE pictures 2021-08-12 4-AMINOANTIPYRINE HYDROCHLORIDE
22198-72-7
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
AMPYRONE HYDROCHLORIDE 4-AMINOPHENAZONE HYDROCHLORIDE 4-AMINOANTIPYRINE HCL 4-AMINO-1,5-DIMETHYL-2-PHENYL-3-PYRAZOLONE HYDROCHLORIDE 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-3h-pyrazol-3-onmonohydrochloride 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one monohydrochloride 4-AMINOANTIPYRINE HYDROCHLORIDE 99% Aminoantipyrine Hydrochloride 4-Aminoantipyrine Hydrochloride [for Biochemical Research] 4-Aminoantipyrine hydrochloride,99% 4-AA HCl 1,5-DIMETHYL-2-PHENYL-4-AMINOPYRAZOLONE HYDROCHLORIDE 4-AMino-1,5-diMethyl-2-phenyl-1H-pyrazol-3(2H)-one hydrochloride 4-Aminoantipyrine Hydrochloride  4-Aminoantipyrine Hydrochloride [for Biochemical Research]> 4-Amino-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-onmonohydrochlorid 4-amino-1,5-dimethyl-2-phenylpyrazol-3-one,hydrochloride Ampyrone HCl 4-amino-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one hydrochloride 4-Aminoantipyrine hydrochloride 22198-72-7