4-Aminoantipyrine hydrochloride
- CAS No.
- 22198-72-7
- Chemical Name:
- 4-Aminoantipyrine hydrochloride
- Synonyms
- 4-AA HCl;Ampyrone HCl;4-AMINOANTIPYRINE HCL;AMPYRONE HYDROCHLORIDE;Aminoantipyrine Hydrochloride;4-AMINOPHENAZONE HYDROCHLORIDE;4-Aminoantipyrine hydrochloride;4-AMINOANTIPYRINE HYDROCHLORIDE 99%;4-Aminoantipyrine hydrochloride,99%;4-Aminoantipyrine Hydrochloride 
- CBNumber:
- CB0726324
- Molecular Formula:
- C11H14ClN3O
- Molecular Weight:
- 239.7
- MDL Number:
- MFCD00042012
- MOL File:
- 22198-72-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 220-225 °C |
|---|---|
| storage temp. | Storage temp. 2-8°C |
| form | powder to crystal |
| color | White to Light yellow to Light orange |
| Water Solubility | almost transparency |
| CAS DataBase Reference | 22198-72-7(CAS DataBase Reference) |
| FDA UNII | F7WGH82I6D |
| EPA Substance Registry System | 3H-Pyrazol-3-one, 4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-, monohydrochloride (22198-72-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 36/37/39-26 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2933.11.0000 | |||||||||
| NFPA 704 |
|
4-Aminoantipyrine hydrochloride price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A0257 | 4-Aminoantipyrine Hydrochloride [for Biochemical Research] >98.0%(HPLC)(T) | 22198-72-7 | 5g | $35 | 2026-04-30 | Buy |
| TCI Chemical | A0257 | 4-Aminoantipyrine Hydrochloride [for Biochemical Research] >98.0%(HPLC)(T) | 22198-72-7 | 25g | $90 | 2026-04-30 | Buy |
| ChemScene | CS-0153632 | 4-Amino-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one hydrochloride ≥95% | 22198-72-7 | 25g | $81 | 2026-06-04 | Buy |
| Chem-Impex | 39280 | 4-Aminoantipyrine hydrochloride [for Biochemical Research] ≥98%(Assaybytitration,HPLC) | 22198-72-7 | 5G | $61.19 | 2026-05-19 | Buy |
| Chem-Impex | 39280 | 4-Aminoantipyrine hydrochloride [for Biochemical Research] ≥98%(Assaybytitration,HPLC) | 22198-72-7 | 25G | $185.18 | 2026-05-19 | Buy |
4-Aminoantipyrine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
faint yellow to orange crystalline powder
Uses
4-Aminoantipyrine (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
Method for synthesizing free base:
1) Prepare a solution of antipyrine with 50% sulfuric acid.
2)Flow the solution and sodium nitrite solution into the nitrosation reactor at the same time, control the flow rate of both, control the reaction temperature 45-50, react under stirring, and measure the reaction endpoint with iodine powder starch test paper to adjust the water flow rate.
3) The nitrosative antipyrine generated by nitrosation immediately flows into the reduction tank and reacts with the aqueous solution of reductant prepared in the tank.
4) Take a sample to measure the pH value, the pH value between 5.4-5.8 when the reduction is over, adjust the pH value to 5.8-6.0, raise the temperature to 100 , hydrolyze for 3h, lower the temperature to 80 , neutralize with liquid ammonia to pH 7-7.5, and leave it to stratify.
5) Separate the waste water to get 4-aminoantipyrine oil, which is pressed into a crystallization tank, stirred, cooled crystallized and filtered to get 4-aminoantipyrine.
4-Aminoantipyrine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
4-Aminoantipyrine hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
View Lastest Price from 4-Aminoantipyrine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-02 | 4-AMINOANTIPYRINE HYDROCHLORIDE
22198-72-7
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
![]() |
2021-08-12 | 4-AMINOANTIPYRINE HYDROCHLORIDE
22198-72-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-

- 4-AMINOANTIPYRINE HYDROCHLORIDE
22198-72-7
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-

- 4-AMINOANTIPYRINE HYDROCHLORIDE
22198-72-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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