Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Chloro-4-hydroxyquinazoline

2-Chloro-4-hydroxyquinazoline

2-Chloro-4-hydroxyquinazoline Structure
2-Chloro-4-hydroxyquinazoline structure
CAS No.
607-69-2
Chemical Name:
2-Chloro-4-hydroxyquinazoline
Synonyms
2-chloroquinazolin-4-ol;2-Chloroquinazolin-4(3H);2-Chloroquinazolin-4-one;2-Chloro-4(1H)-quinazolinone;2-chloroquinazolin-4(1H)-one;2-Chloro-4-hydroxyquinazoline;4(3H)-Quinazolinone, 2-chloro-;2-chloro-3,4-dihydroquinazolin-4-one
CBNumber:
CB0741451
Molecular Formula:
C8H5ClN2O
Molecular Weight:
180.59
MDL Number:
MFCD04086742
MOL File:
607-69-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:48:28
Request For Quotation

2-Chloro-4-hydroxyquinazoline Properties

Melting point 218-220℃
Boiling point 325.9±25.0 °C(Predicted)
Density 1.50
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -2.12±0.20(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

2-Chloro-4-hydroxyquinazoline price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR322827 2-Chloro-3H-quinazolin-4-one 97% 607-69-2 100mg $32 2026-06-04 Buy
Apolloscientific OR322827 2-Chloro-3H-quinazolin-4-one 97% 607-69-2 250mg $37 2026-06-04 Buy
Apolloscientific OR322827 2-Chloro-3H-quinazolin-4-one 97% 607-69-2 1g $98 2026-06-04 Buy
AK Scientific Z4933 2-Chloroquinazolin-4(3H)-one 97% 607-69-2 250mg $42 2026-06-04 Buy
AK Scientific Z4933 2-Chloroquinazolin-4(3H)-one 97% 607-69-2 1g $121 2026-06-04 Buy
Product number Packaging Price Buy
OR322827 100mg $32 Buy
OR322827 250mg $37 Buy
OR322827 1g $98 Buy
Z4933 250mg $42 Buy
Z4933 1g $121 Buy

2-Chloro-4-hydroxyquinazoline Chemical Properties, Uses, Production

Uses

2-Chloroquinazolin-4(3H)-one is used in the preparation of some quinazoline derivatives with multiple biological properties.

Synthesis

2,4-Dichloroquinazoline

607-68-1

2-CHLORO-4-HYDROXYQUINAZOLINE

607-69-2

General procedure for the synthesis of 2-chloroquinazolin-4-one from 2,4-dichloroquinazoline: 2,4-dichloroquinazoline (0.72 g, 3.62 mmol) was dissolved in tetrahydrofuran (6 mL), followed by the addition of aqueous sodium hydroxide solution (8 mL, 1 mol/L). The reaction mixture was stirred and reacted at room temperature overnight. Upon completion of the reaction, the pH of the reaction solution was adjusted to 5-6 with acetic acid to terminate the reaction. The reaction mixture was filtered and the filtrate was concentrated to dryness under reduced pressure to give 2-chloroquinazolin-4-one (0.60 g, 91.9% yield) as a yellow solid.

References

[1] Organic Process Research and Development, 2004, vol. 8, # 3, p. 330 - 340
[2] Journal of Medicinal Chemistry, 1986, vol. 29, # 5, p. 627 - 629
[3] European Journal of Organic Chemistry, 2012, # 11, p. 2118 - 2122
[4] Patent: CN105732591, 2016, A. Location in patent: Paragraph 0311; 0312; 0313; 0314
[5] Journal of Medicinal Chemistry, 2007, vol. 50, # 10, p. 2297 - 2300

2-Chloro-4-hydroxyquinazoline Preparation Products And Raw materials

Raw materials

2,4-Dichloroquinazoline Sodium hydroxide Water Tetrahydrofuran

Preparation Products

2-Chloro-4-hydroxyquinazoline Suppliers

Global Suppliers ( 80)
Supplier Tel Email Country ProdList Advantage
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Carbott PharmTech Inc. 0535-6385396 info@carbottpharm.com China 996 56
Atop-Pharma (Shanghai) Technology Co., Ltd. +86 (21) 5196-9732 China 996 57
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3996 55
Shanghai Raise Chemical Technology Co.,Ltd 15026594951 rs@raise-chem.com China 4904 55
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Shanghai Carlow Chemicals Co., Ltd. 21-33526724 18930996265 info@carlowchem.com China 1996 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Chiral bio-compound co., Ltd. 021-5068 3667/17749785980/1029026415; 17749785980 1029026415@qq.com China 4501 58
Supplier Advantage
PharmaBlock Sciences (Nanjing),Inc. 55
Carbott PharmTech Inc. 56
Atop-Pharma (Shanghai) Technology Co., Ltd. 57
Shanghai Sphchem Co., Ltd. 55
Chiba Pharmaceutical Science and technology Co, Ltd. 55
Shanghai Raise Chemical Technology Co.,Ltd 55
Shanghai Raise Chemical Technology Co.,Ltd 55
Shanghai Carlow Chemicals Co., Ltd. 58
Bide Pharmatech Ltd. 60
Shanghai Chiral bio-compound co., Ltd. 58

View Latest Price from 2-Chloro-4-hydroxyquinazoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloroquinazolin-4(3H)-one pictures 2019-07-10 2-Chloroquinazolin-4(3H)-one
607-69-2
 $8.80 1KG 97%-99% 100kg Career Henan Chemical Co

2-Chloro-4-hydroxyquinazoline Spectrum

2-CHLORO-4-HYDROXYQUINAZOLINE(607-69-2)1HNMR

607-69-2 (2-Chloro-4-hydroxyquinazoline) Related Search:

2-Chloro-6,7-dimethoxy-quinazolin-4-ol 4-(Benzyloxy)-2-chloro-6,7-dimethoxyquinazoline 2,7-Dichloroquinazolin-4-ol 2-Chloro-4,6-dimethoxyquinazoline 2-Chloro-4-methoxyquinazoline
2-Chloro-4-hydroxyquinazoline 4-Hydroxyquinazoline 1-((2-Chloro-6,7-dimethoxy-4-quinazolinyl)oxy)-3-((1-methylethyl)amino )-2-propanol

1of2

4(3H)-Quinazolinone, 2-chloro- 2-Chloro-4(1H)-quinazolinone 2-Chloroquinazolin-4-one 2-chloroquinazolin-4-ol 2-Chloroquinazolin-4(3H) 2-chloro-3,4-dihydroquinazolin-4-one 2-chloroquinazolin-4(1H)-one 2-Chloro-4-hydroxyquinazoline 607-69-2