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5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE

5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE structure

CAS No.: 183208-36-8

Chemical Name:: 5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE

Synonyms: 5-METHOXY-7-AZAINDOLE;5-Methoxyl-7-azaindole;5-Methoxyl-8-azaindole;5-methoxy-1H-pyrrolopyridine;5-METHOXY-1H-PYRROLO[2,3-B]PYR;5-Methoxy-1H-pyrrolo[2,3-b]pyridin;5-Metho×y-1H-pyrrolo[2,3-b]pyridine;5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE;5-methoxy-1H-pyrrolo[2,3-b]x pyridine;1H-Pyrrolo[2,3-b]pyridine, 5-methoxy-

CBNumber:: CB0747958

Molecular Formula:: C8H8N2O

Molecular Weight:: 148.16

MDL Number:: MFCD06659675

MOL File:: 183208-36-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 22:55:22

Product description	Number	Pack Size	Price
5-Methoxy-1H-pyrrolo[2,3-b]pyridine Aldrich	ADE000892	1g	$761
5-Methoxy-1H-pyrrolo[2,3-b]pyridine 98%	OR964856	250mg	$21
5-Methoxy-1H-pyrrolo[2,3-b]pyridine 98%	OR964856	1g	$24
5-Methoxy-1H-pyrrolo[2,3-b]pyridine 98%	OR964856	5g	$66
5-Methoxy-1H-pyrrolo[2,3-b]pyridine 98%	OR964856	25g	$248
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5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE Properties

Boiling point	412.1±45.0 °C(Predicted)
Density	1.24
storage temp.	Sealed in dry,Room Temperature
pka	7.24±0.20(Predicted)
Appearance	white solid
InChI	InChI=1S/C8H8N2O/c1-11-7-4-6-2-3-9-8(6)10-5-7/h2-5H,1H3,(H,9,10)
InChIKey	AFUFCCUQHGSNAN-UHFFFAOYSA-N
SMILES	C12NC=CC1=CC(OC)=CN=2

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338
Hazard Codes	Xi,Xn
Risk Statements	22
Safety Statements	24/25
WGK Germany	3
HazardClass	IRRITANT
HS Code	29339900

5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	ADE000892	5-Methoxy-1H-pyrrolo[2,3-b]pyridine Aldrich	183208-36-8	1g	$761	2023-01-07	Buy
Apolloscientific	OR964856	5-Methoxy-1H-pyrrolo[2,3-b]pyridine 98%	183208-36-8	250mg	$21	2026-06-04	Buy
Apolloscientific	OR964856	5-Methoxy-1H-pyrrolo[2,3-b]pyridine 98%	183208-36-8	1g	$24	2026-06-04	Buy
Apolloscientific	OR964856	5-Methoxy-1H-pyrrolo[2,3-b]pyridine 98%	183208-36-8	5g	$66	2026-06-04	Buy
Apolloscientific	OR964856	5-Methoxy-1H-pyrrolo[2,3-b]pyridine 98%	183208-36-8	25g	$248	2026-06-04	Buy

Product number	Packaging	Price	Buy
ADE000892	1g	$761	Buy
OR964856	250mg	$21	Buy
OR964856	1g	$24	Buy
OR964856	5g	$66	Buy
OR964856	25g	$248	Buy

5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE Chemical Properties,Uses,Production

Chemical Properties

Tan solid

Uses

5-Methoxy-7-azaindole can be used as a pharmaceutical intermediate, mainly used in laboratory research and development processes and chemical production processes, especially in the synthesis of drug molecules with specific biological activities.

Synthesis

124-41-4

183208-35-7

183208-36-8

General procedure for the synthesis of 5-methoxy-1H-pyrrolo[2,3-b]pyridine (30) from sodium methanol and 5-bromo-7-azaindole: to a solution of 5-bromo-7-azaindole (0.98 g, 5.0 mmol) in DMF (32 mL) was added a 25% (w/w) solution of sodium methanol (48 mL, 210 mmol), followed by addition of copper(I) bromide (1.43 g, 10.0 mmol). The reaction mixture was heated at 140 °C for 2.5 hours. After completion of the reaction, the reaction mixture was cooled and concentrated under reduced pressure to remove DMF. water (100 mL) and saturated aqueous sodium bicarbonate (20 mL) were added to the residue. The aqueous phase was extracted with ethyl acetate (3 x 100 mL), the organic phases were combined and dried over anhydrous magnesium sulfate. After filtration, the organic phase was concentrated under reduced pressure to obtain the crude product. The crude product was purified by silica gel column chromatography (ethyl acetate:hexane, gradient elution to 30:70) to afford the target compound 30 as a green solid (0.58 g, 78% yield).1H NMR (400 MHz, CDCl3) δ 3.90 (s, 3H), 6.45 (d, J = 2.3 Hz, 1H), 7.33 (d, J = 2.8 Hz, 1H ), 7.48 (d, J = 2.2 Hz, 1H), 8.00-8.20 (bs, 1H), 10.60-10.80 (bs, NH).

References

[1] Journal of the American Chemical Society, 2006, vol. 128, # 45, p. 14426 - 14427
[2] Patent: EP1749829, 2007, A1. Location in patent: Page/Page column 52
[3] Patent: US2007/72896, 2007, A1. Location in patent: Page/Page column 51
[4] Patent: WO2012/88469, 2012, A1. Location in patent: Page/Page column 175-177
[5] Patent: WO2007/2325, 2007, A1. Location in patent: Page/Page column 122

5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE Preparation Products And Raw materials

Raw materials

Methanol Sodium Methoxide 5-Bromo-7-azaindole Cuprous bromide N,N-Dimethylformamide

Preparation Products

1H-PYRROLO[2,3-B]PYRIDIN-5-OL

5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE Suppliers

Global( 164)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+86-15350571055	Sibel@chuanghaibio.com	China	8737	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Shanghai Arbor Chemical Co., Ltd.	021-60451682	act@arborchemical.com	CHINA	903	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63645	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21135	58
Zhengzhou Alfa Chemical Co.,Ltd	+86-18530059196	sale04@alfachem.cn	China	9636	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17339	58
KARMEL TECHNOLOGY (HK) CO.,LIMITED	+8618795957998	karmelhk@126.com	CHINA	2886	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Shanghai Arbor Chemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Zhengzhou Alfa Chemical Co.,Ltd	58
SIMAGCHEM CORP	58
KARMEL TECHNOLOGY (HK) CO.,LIMITED	58

View Lastest Price from 5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE 183208-36-8	$1.00	1kg	99%	10 m	Hebei Chuanghai Biotechnology Co., Ltd
2025-11-18	5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE 183208-36-8	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2019-07-06	5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE 183208-36-8	$1.00	1KG	99%		Career Henan Chemical Co

5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE
183208-36-8
$1.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE
183208-36-8
$1.10
99.00%
Dideu Industries Group Limited

5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE
183208-36-8
$1.00
99%
Career Henan Chemical Co

5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE Spectrum

5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE(183208-36-8)¹HNMR

183208-36-8(5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE)Related Search:

3-(Cyanomethyl)-5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ,96%,3-(CYANOMETHYL)-5-METHOXY-1H-PYRROLO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID 3-IODO-5-METHOXY-1H-PYRROLO[3,2-B]PYRIDINE 5-METHOXY-1H-PYRROLO[3,2-B]PYRIDINE-3-CARBALDEHYDE ETHYL 3-((DIMETHYLAMINO)METHYL)-5-METHOXY-1H-PYRROLO[2,3-C]PYRIDINE-2-CARBOXYLATE 5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ,98%,5-METHOXY-1H-PYRROLO[2,3-C]PYRIDINE-2-CARBOXYLIC ACID

5-Methoxy-1H-pyrrolo[2,3-c]pyridine 5-METHOXY-1H-PYRROLO[3,2-B]PYRIDINE 5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE 5-METHOXY-2-VINYL-1H-PYRROLO[3,2-B]PYRIDINE 4-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE

(4-METHOXY-1H-PYRROLO[2,3-B]PYRIDIN-2-YL)METHANOL 5-Methoxy-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid ,97%,5-METHOXY-1H-PYRROLO[3,2-B]PYRIDINE-2-CARBOXYLIC ACID METHYL 4-METHOXY-1H-PYRROLO[3,2-C]PYRIDINE-2-CARBOXYLATE,4-METHOXY-1H-PYRROLO[3,2-C]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER ETHYL 4-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE-2-CARBOXYLATE 5-METHOXY-1H-PYRROLO[3,2-B]PYRIDINE-2-CARBALDEHYDE,5-Methoxy-1H-pyrrolo[3,2-b]pyridine-2-carbaldehyde ,97%

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5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE 5-METHOXY-7-AZAINDOLE 1H-Pyrrolo[2,3-b]pyridine,5-methoxy-(9CI) 1H-Pyrrolo[2,3-b]pyridine, 5-methoxy- 5-Methoxyl-7-azaindole 5-METHOXY-1H-PYRROLO[2,3-B]PYR 5-methoxy-1H-pyrrolopyridine 5-Metho×y-1H-pyrrolo[2,3-b]pyridine 5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE ISO 9001：2015 REACH 5-methoxy-1H-pyrrolo[2,3-b]x pyridine 5-Methoxyl-8-azaindole 5-Methoxy-1H-pyrrolo[2,3-b]pyridin 5-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE，98%ｍｉｎ 183208-36-8 PYRIDINE Azaindoles