2-Fluoro-4-pyridinemethanol
- CAS No.
- 131747-60-9
- Chemical Name:
- 2-Fluoro-4-pyridinemethanol
- Synonyms
- (2-Fluoropyridin-4-yl)methanol;2-Fluoro-4-pyridinemethanol;(2-fluoro-4-pyridyl)methanol;4-PyridineMethanol, 2-fluoro-;2-Fluoro-4-hydroxymethylpyridine;2-Fluoro-4-pyridinemethanol ,96%;4-Pyridinemethanol,2-fluoro-(9CI);(2-fluoro-4-pyridyl)methanol - [F82319]
- CBNumber:
- CB0752138
- Molecular Formula:
- C6H6FNO
- Molecular Weight:
- 127.12
- MDL Number:
- MFCD06200782
- MOL File:
- 131747-60-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 59.3-60.4 °C |
|---|---|
| Boiling point | 247.4±25.0 °C(Predicted) |
| Density | 1.262±0.06 g/cm3(Predicted) |
| storage temp. | Storage temp. 2-8°C |
| form | solid |
| pka | 13.05±0.10(Predicted) |
| Appearance | White to off-white Solid |
| InChI | 1S/C6H6FNO/c7-6-3-5(4-9)1-2-8-6/h1-3,9H,4H2 |
| InChIKey | IAFXOPAZVVMMLE-UHFFFAOYSA-N |
| SMILES | Fc1nccc(c1)CO |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H315-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Hazard Codes | F |
| Risk Statements | 10-36/37/38-20/21/22 |
| Safety Statements | 16-26-36 |
| WGK Germany | WGK 3 |
| HazardClass | IRRITANT |
| HS Code | 29333990 |
| Storage Class | 11 - Combustible Solids |
2-Fluoro-4-pyridinemethanol price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | MNO000064 | (2-Fluoropyridin-4-yl)methanol Aldrich | 131747-60-9 | 1g | $197 | 2026-04-30 | Buy |
| Usbiological | 230355 | 2-Fluoropyridine-4-methanol ≥96% (GC) ≥96%(GC) | 131747-60-9 | 250mg | $245 | 2026-06-03 | Buy |
| Usbiological | 230355 | 2-Fluoropyridine-4-methanol ≥96% (GC) ≥96%(GC) | 131747-60-9 | 1g | $340 | 2026-06-03 | Buy |
| Usbiological | 230355 | 2-Fluoropyridine-4-methanol ≥96% (GC) ≥96%(GC) | 131747-60-9 | 5g | $1042 | 2026-06-03 | Buy |
| Apolloscientific | PC905392 | (2-Fluoropyridin-4-yl)methanol 97% | 131747-60-9 | 250mg | $25 | 2026-06-04 | Buy |
2-Fluoro-4-pyridinemethanol Chemical Properties, Uses, Production
Chemical Properties
Light yellow low melting solid
Synthesis
1006300-11-3
131747-60-9
General procedure for the synthesis of 2-fluoro-4-pyridinemethanol (37) from 2-fluoro-4-pyridinecarboxylic acid phenylmethyl ester (36) (4.536 g, 19.62 mmol): to a stirred solution of 2-fluoro-4-pyridinecarboxylic acid phenylmethyl ester (36) in anhydrous methanol (40 mL) was added sodium methanolate (1.06 g, 19.62 mmol) under ice bath cooling. After stirring for 30 min, an excess of ammonium chloride was added to the reaction mixture. Subsequently, the mixture was concentrated by evaporation under vacuum and the residue was purified by silica gel column chromatography (eluent: ether/hexane, 1:1, v/v) to afford 2.34 g (94% yield) of 2-fluoro-4-pyridinylmethanol (37) as a white solid with a melting point of 70-71°C. 1H NMR (200 MHz, CDCl3) δ: 2.40 (1H, t, J = 4.0 Hz), 4.78 (2H, d, J = 4.0 Hz), 6.97 (1H, s), 7.15 (1H, m), 8.15 (1H, d, J = 5.0 Hz); Mass Spectrum (EI): m/z 127 (M+).
References
[1] Patent: US2008/70920, 2008, A1. Location in patent: Page/Page column 37-38
[2] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 5, p. 1585 - 1588
2-Fluoro-4-pyridinemethanol Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9848 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Bellen Chemistry Co., Ltd. | 010-60400365-8001 15910885229 | service@bellenchem.com | China | 4514 | 60 |
| JW & Y Pharmlab Co., Ltd. | 021-64340559 | xinyu_shi@jwypharmlab.com.cn | China | 11999 | 58 |
| Shanghai Chenzhu Pharmaceutical Co., Ltd. | 13162380607 | 1696175688@qq.com | China | 834 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| parabiochem | 025-83453382-8005 | sale@parabiochem.com | China | 9577 | 55 |
View Latest Price from 2-Fluoro-4-pyridinemethanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-03 | 2-FLUORO-4-PYRIDINEMETHANOL
131747-60-9
|
$1.00 | 1KG | 99% | 10000KGS | Career Henan Chemical Co |
-
- 2-FLUORO-4-PYRIDINEMETHANOL
131747-60-9
- $1.00
- 99%
- Career Henan Chemical Co
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