ChemicalBook >> CAS DataBase List >>2,3-Difluoropyridine-4-carboxylic acid
2,3-Difluoropyridine-4-carboxylic acid
- CAS No.
- 851386-31-7
- Chemical Name:
- 2,3-Difluoropyridine-4-carboxylic acid
- Synonyms
- 2,3-Difluoroisonicotinic acid;2,3-Fifluoroisonicotinic acid;2,3-Difluoro-4-carboxypyridine;2,3-Difluoroisonicotinic acid 97%;2,3-difluoro-4-pyridinecarboxylic acid;2,3-Difluoropyridine-4-carboxylic acid;2,3-difluoroisonicotinic acid, 98%min;4-Pyridinecarboxylic acid, 2,3-difluoro-;2,3-Difluoropyridine-4-carboxylicacid,97%;2,3-Difluoropyridine-4-carboxylic acid ISO 9001：2015 REACH
- CBNumber:
- CB11471031
- Molecular Formula:
- C6H3F2NO2
- Molecular Weight:
- 159.09
- MDL Number:
- MFCD09031174
- MOL File:
- 851386-31-7.mol
- MSDS File:
- SDS
Last updated:2026-01-13 11:13:28
| Product description | Number | Pack Size | Price |
| 2,3-Difluoropyridine-4-carboxylic acid 97% | 759392 | 1g | $68.9 |
| 2,3-Difluoroisonicotinic Acid >98.0%(GC)(T) | D5131 | 1g | $24 |
| 2,3-Difluoroisonicotinic Acid >98.0%(GC)(T) | D5131 | 5g | $105 |
| 2,3-Difluoropyridine-4-carboxylic acid | D445393 | 500mg | $75 |
| 2,3-Difluoroisonicotinic acid | FD63571 | 5G | $80 |
| More product size | |||
| Melting point | 159-160 °C |
|---|---|
| Boiling point | 377.4±37.0 °C(Predicted) |
| Density | 1.535 |
| storage temp. | 2-8°C |
| solubility | soluble in Methanol |
| pka | 2.10±0.10(Predicted) |
| form | powder to crystal |
| color | White to Orange to Green |
| InChI | 1S/C6H3F2NO2/c7-4-3(6(10)11)1-2-9-5(4)8/h1-2H,(H,10,11) |
| InChIKey | FFGHMEKFPCGYEG-UHFFFAOYSA-N |
| SMILES | OC(=O)c1ccnc(F)c1F |
| CAS DataBase Reference | 851386-31-7 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H302 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
2,3-Difluoropyridine-4-carboxylic acid price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 759392 | 2,3-Difluoropyridine-4-carboxylic acid 97% | 851386-31-7 | 1g | $68.9 | 2023-06-20 | Buy |
| TCI Chemical | D5131 | 2,3-Difluoroisonicotinic Acid >98.0%(GC)(T) | 851386-31-7 | 1g | $24 | 2026-03-19 | Buy |
| TCI Chemical | D5131 | 2,3-Difluoroisonicotinic Acid >98.0%(GC)(T) | 851386-31-7 | 5g | $105 | 2026-03-19 | Buy |
| TRC | D445393 | 2,3-Difluoropyridine-4-carboxylic acid | 851386-31-7 | 500mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD63571 | 2,3-Difluoroisonicotinic acid | 851386-31-7 | 5G | $80 | 2021-12-16 | Buy |
2,3-Difluoropyridine-4-carboxylic acid Chemical Properties,Uses,Production
Uses
2,3-Difluoropyridine-4-carboxylic acid is particularly important as starting materials for agrochemicals and pharmaceuticals.
Synthesis
To a solution of n-BuLi (26.1 mL, 52.09 mmol) in THF (70 mL, Na distilled) was added N,N-diisopropylamine (7.30 mL, 52.09 mmol) and 2,3-difluoropyridine (5.00 g, 43.41 mmol) successively at -78 C. The resulting mixture was stirred at -78C for 1 hour and then poured over crushed dry ice (excess). The reaction was allowed to warm up to room temperature for 1 h and after evaporation of the excess dry ice and THF, the residue was added to water (100 mL) and washed with EtOAc (2 x 50 mL). The aqueous layer was then acidified to pH 1 and extracted with EtOAc (2 x 100 mL). The combined organic extracts were dried and evaporated to give the product 2,3-difluoropyridine-4-carboxylic acid. Yield = 2.39 g, 35%.
2,3-Difluoropyridine-4-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 196)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 10000 | 58 |
| Alfa Chemistry | info@alfa-chemistry.com | United States | 2344 | 58 |
View Lastest Price from 2,3-Difluoropyridine-4-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | 2,3-Difluoropyridine-4-carboxylic acid
851386-31-7
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-04-04 | 2,3-Difluoropyridine-4-carboxylic acid
851386-31-7
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2019-07-12 | 2,3-Difluoropyridine-4-carboxylic acid
851386-31-7
|
US $1.00 / KG | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- 2,3-Difluoropyridine-4-carboxylic acid
851386-31-7
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- 2,3-Difluoropyridine-4-carboxylic acid
851386-31-7
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2,3-Difluoropyridine-4-carboxylic acid
851386-31-7
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
851386-31-7(2,3-Difluoropyridine-4-carboxylic acid)Related Search:
2,3-Difluoropyridine-4-carboxylic acid
4-Pyridinecarboxylic acid, 2,3-difluoro-
2,3-Difluoropyridine-4-carboxylic acid, 4-Carboxy-2,3-difluoropyridine
2,3-Difluoro-4-carboxypyridine
2,3-Fifluoroisonicotinic acid
2,3-difluoro-4-pyridinecarboxylic acid
2,3-Difluoroisonicotinic acid
2,3-Difluoroisonicotinic acid 97%
2,3-Difluoropyridine-4-carboxylicacid,97%
2,3-Difluoropyridine-4-carboxylic acid ISO 9001：2015 REACH
2, 3-difluoroisonicotinic acid /2, 3-difluoropyridine-4-carboxylic acid
2,3-difluoroisonicotinic acid, 98%min
851386-31-7
Fluorine series
