COX-2 (human) Monoclonal Antibody (Clone CX229)
- CAS No.
- Chemical Name:
- COX-2 (human) Monoclonal Antibody (Clone CX229)
- Synonyms
- COX-2 (human) Monoclonal Antibody (Clone CX229)
- CBNumber:
- CB07533808
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
COX-2 (human) Monoclonal Antibody (Clone CX229) Chemical Properties,Uses,Production
Description
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2; ), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2 . COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosynthesis of PGs under acute inflammatory conditions. Thus, COX-2 has been the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development. Cayman''s COX-2 (human) Monoclonal Antibody (Clone CX229) can be used for immunohistochemistry (IHC) and Western blot (WB) applications. The antibody recognizes a unique C-terminal region of COX-2 that is not present in COX-1, specifically detecting COX-2 ~70 kDa from human and ovine samples.
References
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COX-2 (human) Monoclonal Antibody (Clone CX229) Preparation Products And Raw materials
Raw materials
Preparation Products
COX-2 (human) Monoclonal Antibody (Clone CX229) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cayman Chemical Company | -- | sales@caymanchem.com | China | 6808 | 58 |
| Shenzhen Campbell Biotechnology Co., Ltd. | -- | CHINA | 6891 | 58 |
| Supplier | Advantage |
|---|---|
| Cayman Chemical Company | 58 |
| Shenzhen Campbell Biotechnology Co., Ltd. | 58 |
