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COX-2 Monoclonal Antibody (Clone 12C10)

COX-2 Monoclonal Antibody (Clone 12C10) structure

CAS No.

Chemical Name:: COX-2 Monoclonal Antibody (Clone 12C10)

Synonyms: COX-2 Monoclonal Antibody (Clone 12C10)

CBNumber:: CB94814455

Molecular Formula:

Molecular Weight:: 0

MDL Number:

MOL File:: Mol file

Last updated:2025-08-20 16:56:28

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COX-2 Monoclonal Antibody (Clone 12C10) price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	20198	COX-2 Monoclonal Antibody (Clone 12C10)		50μg	$347	2026-04-30	Buy

Product number	Packaging	Price	Buy
20198	50μg	$347	Buy

COX-2 Monoclonal Antibody (Clone 12C10) Chemical Properties,Uses,Production

Description

Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) to the hydroperoxy endoperoxide prostaglandin G₂ (PGG₂; ), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH₂ . COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosynthesis of PGs under acute inflammatory conditions. Thus, COX-2 has been the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development. Cayman''s COX-2 Monoclonal Antibody (Clone 12C10) can be used for ELISA, flow cytometry (FC), immunofluorescence (IF), and Western blot (WB) applications. The antibody recognizes a unique C-terminal region of COX-2 that is not present in COX-1, specifically detecting COX-2 at 72 kDa from human, mouse, and ovine samples.

References

[1] JIALI FANG. Epigenetic changes mediated by microRNA miR29 activate cyclooxygenase 2 and lambda-1 interferon production during viral infection.[J]. ACS Applied Energy Materials, 2012: 1010-1020. DOI: 10.1128/jvi.06169-11

COX-2 Monoclonal Antibody (Clone 12C10) Preparation Products And Raw materials

Raw materials

Preparation Products

COX-2 Monoclonal Antibody (Clone 12C10) Suppliers

Global( 4)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Universal Biotech Co.,Ltd	15921930842 15921930842	yh-wang@univ-bio.com	China	25030	58

Supplier	Advantage
Shanghai Universal Biotech Co.,Ltd	58

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COX-2 Monoclonal Antibody (Clone 12C10)