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2-Fluoro-4-methylbenzoic acid

2-Fluoro-4-methylbenzoic acid structure

CAS No.: 7697-23-6

Chemical Name:: 2-Fluoro-4-methylbenzoic acid

Synonyms: RARECHEM AL BO 2237;2-Fluoro-p-toluic Acid;4-Carboxy-3-fluorotoluene;2-Fluoro-4-methylbenzoicaci;2-FLUORO-4-METHYLBENZOIC ACID;2-Fluoro-4-methylbenzoicAcid>Benzoic acid, 2-fluoro-4-methyl-;4-Carboxy-3-fluorotoluene, 2-Fluoro-p-toluic acid

CBNumber:: CB0754783

Molecular Formula:: C8H7FO2

Molecular Weight:: 154.14

MDL Number:: MFCD03092906

MOL File:: 7697-23-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 22:51:19

Product description	Number	Pack Size	Price
2-Fluoro-4-methylbenzoic Acid >98.0%(GC)(T)	F0813	1g	$43
2-Fluoro-4-methylbenzoic Acid >98.0%(GC)(T)	F0813	5g	$128
2-Fluoro-4-methylbenzoic acid	FF64207	1g	$150
2-Fluoro-4-methylbenzoic acid	FF64207	5g	$150
2-Fluoro-4-methylbenzoic acid	FF64207	2g	$150
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2-Fluoro-4-methylbenzoic acid Properties

Melting point	186-189°C
Boiling point	271.7±20.0 °C(Predicted)
Density	1.258±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Methanol
form	powder to crystal
pka	3.44±0.10(Predicted)
color	White to Light yellow to Light orange
InChI	InChI=1S/C8H7FO2/c1-5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)
InChIKey	ALFWHEYHCZRVLO-UHFFFAOYSA-N
SMILES	C(O)(=O)C1=CC=C(C)C=C1F
CAS DataBase Reference	7697-23-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-22

Safety Statements

26-36-37

HazardClass

IRRITANT

HS Code

29163990

NFPA 704

	0
2		0

2-Fluoro-4-methylbenzoic acid price More Price(66)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	F0813	2-Fluoro-4-methylbenzoic Acid >98.0%(GC)(T)	7697-23-6	1g	$43	2026-04-30	Buy
TCI Chemical	F0813	2-Fluoro-4-methylbenzoic Acid >98.0%(GC)(T)	7697-23-6	5g	$128	2026-04-30	Buy
Biosynth	FF64207	2-Fluoro-4-methylbenzoic acid	7697-23-6	1g	$150	2026-06-04	Buy
Biosynth	FF64207	2-Fluoro-4-methylbenzoic acid	7697-23-6	5g	$150	2026-06-04	Buy
Biosynth	FF64207	2-Fluoro-4-methylbenzoic acid	7697-23-6	2g	$150	2026-06-04	Buy

Product number	Packaging	Price	Buy
F0813	1g	$43	Buy
F0813	5g	$128	Buy
FF64207	1g	$150	Buy
FF64207	5g	$150	Buy
FF64207	2g	$150	Buy

2-Fluoro-4-methylbenzoic acid Chemical Properties,Uses,Production

Chemical Properties

Light yellow to dark yellow solid

Uses

2-Fluoro-4-methylbenzoic Acid is a useful reagent for preparing tubulin inhibitors for antitumor agents.

Synthesis

352-70-5

865-47-4

7697-23-6

Step A: 3-Fluorotoluene (Compound 1, 18.7 g, 170 mmol) was added to a 500 mL three-necked flask under nitrogen protection and cooled to -78 °C. Subsequently, a THF solution of potassium tert-butoxide (11.0 g, 170 mmol) was slowly added via syringe.After 10 min, a pentane solution of tert-butyllithium (19.0 g, 170 mmol) was slowly added via cannula. The reaction mixture was stirred at -78 °C for 2.5 hours. Upon completion of the reaction, the reaction was quenched with a large amount of crushed fresh dry ice, removed from the -78 °C bath and manually stirred with a metal spatula until the dark brown substance was transformed into a light yellow slurry. After 20 minutes of manual mixing, approximately 500 mL of water was added and the reaction mixture continued to be stirred. Subsequently, the reaction mixture was washed with ether (Et2O) and then acidified with 6N hydrochloric acid to pH less than 3 and extracted again with ether. The organic phases were combined, washed with brine, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated to give compound 2 (10 g, 45% yield).1H NMR (400 MHz, CDCl3) δ 7.90 (t, 1H), 7.04 (d, 1H), 6.97 (d, 1H), 2.39 (s, 3H).

References

[1] Patent: US2004/176325, 2004, A1. Location in patent: Page/Page column 31; sheet 33

2-Fluoro-4-methylbenzoic acid Preparation Products And Raw materials

Raw materials

3-Fluorotoluene Potassium tert-butoxide Tetrahydrofuran Pentane tert-Butyllithium

Preparation Products

4-Fluoro-2-methylbenzoic acid Benzoic acid, 2-fluoro-4-methyl-5-nitro- (9CI) 4-(Bromomethyl)-2-fluorobenzoicacid

2-Fluoro-4-methylbenzoic acid Suppliers

Global( 288)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Speranza Chemical Co., Ltd.	+86-86-075521030354 +86-18688942810	sophieliu@speranzachem.com	China	923	55
Hebei Chuanghai Biotechnology Co., Ltd	+86-15350571055	Sibel@chuanghaibio.com	China	8737	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	809	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10399	58
Accela ChemBio Inc.	+1-858-6993322 +86-18019713315	info@accelachem.com	United States	21189	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114	sales@amoychem.com	China	6361	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88298848	info@edengenechem.com	China	2163	58

Supplier	Advantage
Speranza Chemical Co., Ltd.	55
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Accela ChemBio Inc.	58
Xiamen AmoyChem Co., Ltd	58
Changzhou Ditong Chemical Co.,Ltd	58

View Lastest Price from 2-Fluoro-4-methylbenzoic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-07	2-fluoro-4-methylbenzoic acid 7697-23-6		1KG	98%	100MT/Year	Speranza Chemical Co., Ltd.
2026-03-20	2-Fluoro-4-methylbenzoic acid 7697-23-6		1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd
2021-08-12	2-Fluoro-4-methylbenzoic acid 7697-23-6	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

2-fluoro-4-methylbenzoic acid
7697-23-6
98%
Speranza Chemical Co., Ltd.

2-Fluoro-4-methylbenzoic acid
7697-23-6
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-Fluoro-4-methylbenzoic acid
7697-23-6
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

2-Fluoro-4-methylbenzoic acid Spectrum

2-Fluoro-4-methylbenzoic acid(7697-23-6)¹HNMR 2-Fluoro-4-methylbenzoic acid(7697-23-6)FT-IR

7697-23-6(2-Fluoro-4-methylbenzoic acid)Related Search:

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2,3,5,6-TETRAFLUORO-4-METHYLBENZOIC ACID 4-CYANO-2-FLUOROBENZOIC ACID 4-ALLYL-2,3,5,6-TETRAFLUOROBENZOIC ACID

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2-FLUORO-4-METHYLBENZOIC ACID RARECHEM AL BO 2237 4-Carboxy-3-fluorotoluene 4-Carboxy-3-fluorotoluene, 2-Fluoro-p-toluic acid 2-Fluoro-p-toluic Acid Benzoic acid, 2-fluoro-4-methyl- 2-Fluoro-4-methylbenzoicAcid> 2-Fluoro-4-methylbenzoicaci 7697-23-6 Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Fluorin-contained Benzoic acid series Fluorine series