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Amino-(3-nitro-phenyl)-acetic acid

CAS No.
30077-08-8
Chemical Name:
Amino-(3-nitro-phenyl)-acetic acid
Synonyms
3-Nitrophenylglycine;RS-3-Nitrophenylglycine;DL-m-Nitrophenylglycine;m-Nitro-DL-phenylglycine;2-Amino-2-(3-nitrophenyl);a-Amino-3-nitrobenzeneacetic acid;Amino-(3-nitro-phenyl)-acetic acid;Benzeneacetic acid, α-amino-3-nitro-;Benzeneacetic acid, a-amino-3-nitro-;2-Amino-2-(3-nitrophenyl)acetic acid
CBNumber:
CB0757885
Molecular Formula:
C8H8N2O4
Molecular Weight:
196.16
MDL Number:
MFCD04966788
MOL File:
30077-08-8.mol
MSDS File:
SDS
Last updated:2026-09-12 18:48:29

Amino-(3-nitro-phenyl)-acetic acid Properties

Melting point 166 °C
Boiling point 370.262±37.00 °C(Press: 760.00 Torr)(predicted)
Density 1.473±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 1.685±0.10(predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

Amino-(3-nitro-phenyl)-acetic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FBA07708 2-amino-2-(3-nitrophenyl)acetic acid 30077-08-8 100mg $342 2026-06-04 Buy
Biosynth FBA07708 2-amino-2-(3-nitrophenyl)acetic acid 30077-08-8 1g $1073.8 2026-06-04 Buy
aablocks AA007JIE AMINO-(3-NITRO-PHENYL)-ACETIC ACID 30077-08-8 1g $990 2026-05-28 Buy
ACHEMBLOCK AD245984 2-amino-2-(3-nitrophenyl)acetic acid 95% 30077-08-8 250MG $240 2026-05-27 Buy
ACHEMBLOCK AD245984 2-amino-2-(3-nitrophenyl)acetic acid 95% 30077-08-8 1G $635 2026-05-27 Buy
Product number Packaging Price Buy
FBA07708 100mg $342 Buy
FBA07708 1g $1073.8 Buy
AA007JIE 1g $990 Buy
AD245984 250MG $240 Buy
AD245984 1G $635 Buy

Amino-(3-nitro-phenyl)-acetic acid Chemical Properties, Uses, Production

Synthesis

2-Amino-2-phenylacetic acid

2835-06-5

AMINO-(3-NITRO-PHENYL)-ACETIC ACID

30077-08-8

General procedure for the synthesis of 2-amino-2-(3-nitrophenyl)acetic acid from 2-amino-2-phenylacetic acid: 2-amino-2-phenylacetic acid (33 mmol, 5 g) was cooled to 0 °C and slowly added to a mixture of concentrated sulfuric acid (98% w/w, 5 mL) and fuming nitric acid (90% w/w, 5 mL). The reaction mixture was stirred at 0 °C for 1 h, followed by continued stirring at room temperature for 30 min. Upon completion of the reaction, hydrolysis was carried out with cold water (60 mL). The pH of the reaction solution was adjusted to neutral by dropwise addition of 10 M ammonia. The resulting mixture was stirred at 4 °C for 10 h. 2-Amino-2-(3-nitrophenyl)acetic acid was isolated by filtration. The product was washed with cold water to give a yellow powdery solid. Yield: 64%. 1H-NMR (DMSO, 200 MHz): δ= 8.27 (s, 1H, H-4), 8.10 (d, J = 8.1 Hz, 1H, H-6), 7.83 (d, J = 7.9 Hz, 1H, H-8), 7.64 (t, J = 7.9 Hz, 1H, H-7), 4.51 (s, 1H, H-2). Elemental analysis: calculated values for C8H8N2O4: C, 48.98; H, 4.11; N, 14.28. measured values: C, 48.92; H, 4.19; N, 14.31.

References

[1] Medicinal Chemistry Research, 2017, vol. 26, # 5, p. 975 - 986
[2] Chemische Berichte, 1885, vol. 18, p. 1181

2835-06-5
30077-08-8
Synthesis of Amino-(3-nitro-phenyl)-acetic acid from 2-Amino-2-phenylacetic acid

Amino-(3-nitro-phenyl)-acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Amino-(3-nitro-phenyl)-acetic acid Suppliers

Global Suppliers ( 26)
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Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Bejing Famous Pharmaceutical Technology Co., Ltd. 010-80339217; 13331045123 2559355526@qq.com China 14180 58
Nanjing crow LuNing pharmaceutical technology co., LTD 13382066392 CHINA 4851 58
Nextpeptide Inc +86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19904 58
Zhejiang Lianshuo Biotechnology Co., Ltd. 18616526224 lianshuo@vip.126.com China 9605 58
TIANJIN JINGYE FINE CHEMICAL CO.,LTD. 18202564928 529439566@qq.com China 489 58
SHAANXI?DIDEU?MEDICHEM CO.LTD 17691182729 17392216275 1073@dideu.com China 9993 58
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales1@amateksci.com China 8528 58
2-Amino-2-(3-nitrophenyl)acetic acid m-Nitro-DL-phenylglycine DL-m-Nitrophenylglycine alpha-Amino-3-nitrobenzeneacetic acid 3-Nitrophenylglycine 2-Amino-2-(3-nitrophenyl) RS-3-Nitrophenylglycine Benzeneacetic acid, a-amino-3-nitro- Benzeneacetic acid, α-amino-3-nitro- a-Amino-3-nitrobenzeneacetic acid Amino-(3-nitro-phenyl)-acetic acid 30077-08-8 pharmacetical