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2-Amino-2-phenylacetic acid

CAS No.
2835-06-5
Chemical Name:
2-Amino-2-phenylacetic acid
Synonyms
2-Phenylglycine;α-phenylglycine;DL-ALPHA-PHENYLGLYCINE;H-DL-PHG-OH;DL-PHENYLGLYCINE;DL-2-PHENYLGLYCINE;DL-α-Phenylglycine;2-Amino-2-phenyL;DL-A-PHENYLGLYCINE;RARECHEM AK ML 0501
CBNumber:
CB1420201
Molecular Formula:
C8H9NO2
Molecular Weight:
151.17
MDL Number:
MFCD00064402
MOL File:
2835-06-5.mol
MSDS File:
SDS
Last updated:2026-02-11 10:48:38
Product description Number Pack Size Price
2-Phenylglycine 95% P25507 100g $57
DL-2-Phenylglycine >98.0%(HPLC)(T) P0326 25g $23
DL-2-Phenylglycine >98.0%(HPLC)(T) P0326 500g $267
DL-α-Phenylglycine P327120 50g $85
DL-a-Phenylglycine 287588 250g $389
More product size

2-Amino-2-phenylacetic acid Properties

Melting point 290 °C (subl.)(lit.)
alpha [α]D20-0.5~+0.5゜ (c=5, dil. HCl)
Boiling point 273.17°C (rough estimate)
Density 1.2023 (rough estimate)
refractive index 1.5810 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility almost transparency in Sodium hydroxide solution
pka 1.94±0.10(Predicted)
form Crystalline Powder
color White to off-white
Water Solubility 115g/L(100 ºC)
Merck 14,7291
BRN 3197862
Major Application detection
InChI 1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)
InChIKey ZGUNAGUHMKGQNY-UHFFFAOYSA-N
SMILES NC(C(O)=O)c1ccccc1
CAS DataBase Reference 2835-06-5(CAS DataBase Reference)
FDA UNII 96S7ZZ1KHE
NIST Chemistry Reference Benzeneacetic acid, «alpha»-amino-, (.+/-.)-(2835-06-5)
EPA Substance Registry System 2-Phenylglycine (2835-06-5)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  F,C
Risk Statements  11-34
Safety Statements  24/25-45-36/37/39-26-16
WGK Germany  3
TSCA  TSCA listed
HS Code  29224999
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

2-Amino-2-phenylacetic acid price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P25507 2-Phenylglycine 95% 2835-06-5 100g $57 2025-07-31 Buy
TCI Chemical P0326 DL-2-Phenylglycine >98.0%(HPLC)(T) 2835-06-5 25g $23 2025-07-31 Buy
TCI Chemical P0326 DL-2-Phenylglycine >98.0%(HPLC)(T) 2835-06-5 500g $267 2025-07-31 Buy
TRC P327120 DL-α-Phenylglycine 2835-06-5 50g $85 2021-12-16 Buy
Usbiological 287588 DL-a-Phenylglycine 2835-06-5 250g $389 2021-12-16 Buy
Product number Packaging Price Buy
P25507 100g $57 Buy
P0326 25g $23 Buy
P0326 500g $267 Buy
P327120 50g $85 Buy
287588 250g $389 Buy

2-Amino-2-phenylacetic acid Chemical Properties,Uses,Production

Description

2-Amino-2-phenylacetic acid is a natural compound that has been identified as a selective inhibitor of cyclooxygenase 2 (COX-2), and it exhibits antiinflammatory activity. It has been shown to inhibit COX-2 at low concentrations and to be less potent than aspirin in inhibiting COX-1. It is also an amide, with a molecular weight of 296. In order to determine the structure of it, XRD data was collected from the monosodium salt form of the compound. The ester hydrochloride form was used for enzyme activity assays because it is more soluble in water than the free base form. The synthesis of 2-Amino-2-phenylacetic acid was achieved through a two step process involving amide formation and hydrolysis.

Chemical Properties

white amorphous powder

Uses

DL-α-Phenylglycine is used as a reagent in the synthesis of benzoquinone-amino acid conjugates which have antibacterial activity.

Definition

ChEBI: An amino acid with a structure in which a phenyl ring is bonded to the alpha-carbon of glycine.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 84, 1955
Synthetic Communications, 2, p. 423, 1972 DOI: 10.1080/00397917208081791

reaction suitability

reaction type: solution phase peptide synthesis

611-73-4
2835-06-5
Synthesis of 2-Amino-2-phenylacetic acid from Benzoylformic acid
Global( 352)Suppliers
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DONBOO AMINO ACID COMPANY
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ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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View Lastest Price from 2-Amino-2-phenylacetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DL-Phenylglycine pictures 2026-02-13 DL-Phenylglycine
2835-06-5
US $0.00 / Kg/Drum 1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
2-Phenylglycine pictures 2026-02-01 2-Phenylglycine
2835-06-5
US $0.00 / removed 98.84% 10g TargetMol Chemicals Inc.
2-Phenylglycine pictures 2026-02-01 2-Phenylglycine
2835-06-5
US $0.00 / removed 98.84% 10g TargetMol Chemicals Inc.
  • DL-Phenylglycine pictures
  • DL-Phenylglycine
    2835-06-5
  • US $0.00 / Kg/Drum
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
RARECHEM AK ML 0501 (.+/-.)-alpha-Phenylglycine (+/-)-benzeneaceticaci .alpha.-amino-,(+-)-Benzeneaceticacid -Aminobenzeneaceticacid Benzeneacetic acid, alpha-amino-, (± Benzeneaceticacid,-amino-,(+-)- PHENYLGLYCINE(D,L-) DL-A-AMINOPHENYLACETIC ACID CRYSTALLINE Benzeneacetic acid, alpha-amino- (9CI) Benzeneacetic acid, .alpha.-amino- (n)-à-aminophenylacetic acid 2-Amino-2-phenylacetic acid 2-Phenylglycine DL-a-Aminophenylglycine acid (±)-α-Aminophenylacetic acid, DL-α-Phenylglycine DL-α-Aminophenylacetic acid 2-Phenyl-DL-glycine rac-(R*)-Aminophenylacetic acid DL-alpha-Phenylglycine,99% DL-2-Phenylglycine (±)-α-Aminophenylacetic acid 2-Phenylglycine,(±)-α-Aminophenylacetic acid, DL-α-Phenylglycine DL-alpha-Phenylglycine, 99% 100GR (-)-1-phenylglycine DL-A-AMINOPHENYLACETIC ACID FOR SYNTHESI Benzeneaceticacid,a-aMino- Glycine, 2-phenyl-, DL- AMINO-PHENYL-ACETIC ACID 2-Phenylglycine 95% DL-A-AMINOPHENYLACETIC ACID DL-2-PHENYLGLYCINE DL-2-AMINOPHENYLACETIC ACID DL-A-PHENYLGLYCINE DL-ALPHA-PHENYLAMINOACETIC ACID DL-ALPHA-PHENYLGLYCINE DL-ALPHA-AMINOPHENYLACETIC ACID DL-PHENYLGLYCINE LABOTEST-BB LT00005726 H-DL-(PHENYL)GLY-OH H-DL-PHG-OH Mezlocillin Impurity 6 2-Amino-2-phenyL Clopidogrel Impurity 28 DL-α-Phenylg151.16 lycine DL-2-Phenylglycine> α-phenylglycine DL-α-Phenylglycine 2-Amino-2-phenylacetic acid USP/EP/BP Chemical Reagent Bloom Tech 2-Amino-2-Phenylacetic Acid CAS?2835-06-5 DL-Phenyl glycine, GR 99%+ 2-Phenylglycine,lactation,Endogenous Metabolite,inhibit,2Phenylglycine,breast,period,milk,Inhibitor,2 Phenylglycine Benzeneacetic acid, α-amino- (+/-)-Alpha-AMinophenylacetic Acid 2-Phenylglycine, 98% 2835-06-5 835-06-5 2383-06-5 2835-06-05