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6-Chloro-1-tetralone

6-Chloro-1-tetralone structure

CAS No.: 26673-31-4

Chemical Name:: 6-Chloro-1-tetralone

Synonyms: 6-chloro-3,4-dihydronaphthalen-1(2H)-one;6-Chloro-3,4-dihydro-2H-naphthalen-1-one;6-chloro-3;5-CHLORO-1-INDOMONE;5-CHLORO-L-INDOMONE;6-Chloro-α-Tetralone;6-Chloro-1-tetralone;6-CHLORO-TETRAL-1-ON;6-Chloro-tetral-1-one;6-chlorotetralin-1-one

CBNumber:: CB0766902

Molecular Formula:: C10H9ClO

Molecular Weight:: 180.63

MDL Number:: MFCD04114377

MOL File:: 26673-31-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-06 20:15:29

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6-Chloro-1-tetralone Properties

Melting point	53 °C
Boiling point	150°C/0.7mmHg(lit.)
Density	1.248±0.06 g/cm3(Predicted)
refractive index	1.59
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to lump
color	White to Yellow to Orange
InChI	InChI=1S/C10H9ClO/c11-8-4-5-9-7(6-8)2-1-3-10(9)12/h4-6H,1-3H2
InChIKey	WQKHERPPDYPMNX-UHFFFAOYSA-N
SMILES	C1(=O)C2=C(C=C(Cl)C=C2)CCC1
CAS DataBase Reference	26673-31-4
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P301+P312+P330

WGK Germany

WGK 3

HS Code

2914390090

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

NFPA 704

	1
1		0

6-Chloro-1-tetralone price More Price(65)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	JRD0960	6-Chloro-3,4-dihydronaphthalen-1(2H)-one	26673-31-4	1g	$379	2026-04-30	Buy
TCI Chemical	C2917	6-Chloro-1-tetralone >96.0%(GC)	26673-31-4	1g	$84	2026-04-30	Buy
TCI Chemical	C2917	6-Chloro-1-tetralone >96.0%(GC)	26673-31-4	5g	$286	2026-04-30	Buy
ChemScene	CS-W004311	6-Chloro-1-tetralone ≥97%	26673-31-4	1g	$10	2026-06-04	Buy
ChemScene	CS-W004311	6-Chloro-1-tetralone ≥97%	26673-31-4	5g	$23	2026-06-04	Buy

Product number	Packaging	Price	Buy
JRD0960	1g	$379	Buy
C2917	1g	$84	Buy
C2917	5g	$286	Buy
CS-W004311	1g	$10	Buy
CS-W004311	5g	$23	Buy

6-Chloro-1-tetralone Chemical Properties, Uses, Production

Uses

6-Chloro-1-tetralone is a novel and potent intermediate used for synthesis of pharmaceutical compounds.

Synthesis

A solution of sodium nitrite (173 mg, 2.51 mmol) in water (5 mL) at 0 °C (ice-bath) was added to a magnetically stirred suspension of 6-Amino-1-tetralone (360 mg, 2.23 mmol) in aqueous hydrochloric acid (10 mL, 6 M) at 0 °C. This reaction mixture was added dropwise to a solution of copper(I) chloride (267 mg, 2.70 mmol) in concentrated hydrochloric acid (5 mL) at 0 °C. It was allowed to warm up to room 100 temperature and stirred for a further 2 h after which it was neutralised with solid sodium carbonate, extracted with ethyl acetate (3 × 20 mL) and concentrated in vacuo to give slightly yellow oil. This material was subjected to flash chromatography (50% chloroform in hexane) and concentration of the appropriate fractions afforded 6-chloro-1-tetralone (180 mg, 45%) as a waxy solid.

References

[1] Patent: US2015/105351, 2015, A1. Location in patent: Paragraph 0440
[2] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 11, p. 1259 - 1262
[3] Organic Letters, 2011, vol. 13, # 24, p. 6488 - 6491
[4] Patent: US2012/302562, 2012, A1. Location in patent: Page/Page column 21
[5] Australian Journal of Chemistry, 2010, vol. 63, # 2, p. 211 - 226

6-Chloro-1-tetralone synthesis

Synthesis of 6-Chloro-1-tetralone from 6-Amino-3,4-dihydro-1(2H)-naphthalenone

6-Chloro-1-tetralone Preparation Products And Raw materials

Raw materials

Benzenebutanoic acid, 3-chloro-, ethyl ester Acetonitrile tert-Butyl nitrite 1-(4-Chlorophenyl)cyclobutanol Copper(II) chloride

6-Amino-3,4-dihydro-1(2H)-naphthalenone

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Preparation Products

1-Naphthalenol, 6-chloro-1,2,3,4-tetrahydro-

6-Chloro-1-tetralone Suppliers

Global Suppliers ( 213)

Supplier	Tel	Email	Country	ProdList	Advantage
Zhengzhou TRIZ Pharmaceutical Technology Co., Ltd.	19943855286	94644163@qq.com	China	1934	56
Changzhou Kechem Bio-Scientific Co., LTD.	0519-68985668 13685222090	sales@kechem.cn	China	26012	58
Wuhan EnTai Technology Development Co,.Ltd	86-27-82330560	2536851935@qq.com	China	346	69
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Shandong Xiya Chemical Co., Ltd	13355009207 13355009207	3007715519@qq.com	China	18722	57

Supplier	Advantage
Zhengzhou TRIZ Pharmaceutical Technology Co., Ltd.	56
Changzhou Kechem Bio-Scientific Co., LTD.	58
Wuhan EnTai Technology Development Co,.Ltd	69
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Capot Chemical Co., Ltd	66
Pure Chemistry Scientific Inc.	62
Accela ChemBio Co.,Ltd.	64
Chemsky（shanghai）International Co.,Ltd.	50
Shandong Xiya Chemical Co., Ltd	57

View Latest Price from 6-Chloro-1-tetralone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-18	6-Chloro-1-tetralone 26673-31-4		1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-09-02	5-chloro-l-indomone 26673-31-4	$1.00-200.00	1KG	99%, 99.5% Sublimated		Henan Fengda Chemical Co., Ltd
2026-07-06	6-Chloro-1-tetralone 26673-31-4	$29.00		99.80%	10g	TargetMol Chemicals Inc.

6-Chloro-1-tetralone
26673-31-4
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

5-chloro-l-indomone
26673-31-4
$1.00-200.00
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

6-Chloro-1-tetralone
26673-31-4
$29.00
99.80%
TargetMol Chemicals Inc.

6-Chloro-1-tetralone Spectrum

6-Chloro-1-tetralone(26673-31-4)¹HNMR 6-Chloro-1-tetralone(26673-31-4)FT-IR

26673-31-4 (6-Chloro-1-tetralone) Related Search:

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6-CHLORO-TETRAL-1-ON 6-Chloro-1-tetralone 6-Chloro-α-Tetralone 5-CHLORO-L-INDOMONE 6-Chloro-tetral-1-one 6-Chloro-3,4-dihydro-2H-naphthalen-1-one 6-Chloro-1-tetralone 98% 6-chlorotetralin-1-one 5-CHLORO-1-INDOMONE 3,4,6-trichloronaphthalen-1(2H)-one 6-chloro-3 1(2H)-Naphthalenone, 6-chloro-3,4-dihydro- 6-Chloro-1-tetralone > 6-Chloro-3,4-dihydro-1(2H)-naphthalenone 6-Chloro-3,4-dihydro-2H-1-naphthone 6-Chloro-1-tetralone, 10 mM in DMSO 6-Chloro-3,4-dihydronaphthalen-1(2H)-one 6-Chloro-3,4-dihydrophthalen-1(2H)-one 6-chloro-3,4-dihydronaphthalen-1(2H)-one 26673-31-4 11