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2,6-Dichloropurine riboside

2,6-Dichloropurine riboside structure

CAS No.: 13276-52-3

Chemical Name:: 2,6-Dichloropurine riboside

Synonyms: 105393;2,6-Dichloropurine r;2,6-DICHLOROPURINE RIBO;2,6-Dichloropurine Ribose;6-Dichloropurine riboside;2,6-dichloropuine nuceotide;2,6-DICHLOROPURINE RIBOSIDE;2,6-Dichloropurine nucleoside;2,6-Dichloro-9H-purine Riboside;2,6-Dichloropurine-9--D-riboside

CBNumber:: CB0776309

Molecular Formula:: C10H10Cl2N4O4

Molecular Weight:: 321.12

MDL Number:: MFCD03411342

MOL File:: 13276-52-3.mol

MSDS File:: SDS

Last updated:2026-07-16 07:06:08

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2,6-Dichloropurine riboside Properties

Melting point	>190°C (dec)
Boiling point	542.2±60.0 °C(Predicted)
Density	2.14±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	DMSO (Slightly), Methanol (Slightly), Water
form	Solid
pka	13.00±0.70(Predicted)
color	White to Off-White
CAS DataBase Reference	13276-52-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

2,6-Dichloropurine riboside price More Price(81)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	31405	2,6-Dichloropurine-9-β-D-riboside ≥98%	13276-52-3	25mg	$90	2026-04-30	Buy
Cayman Chemical	31405	2,6-Dichloropurine-9-β-D-riboside ≥98%	13276-52-3	50mg	$158	2026-04-30	Buy
Cayman Chemical	31405	2,6-Dichloropurine-9-β-D-riboside ≥98%	13276-52-3	100mg	$297	2026-04-30	Buy
Cayman Chemical	31405	2,6-Dichloropurine-9-β-D-riboside ≥98%	13276-52-3	500mg	$783	2026-04-30	Buy
Usbiological	295736	2,6-Dichloro-9-(b-D-ribofuranosyl)purine Asreported	13276-52-3	250mg	$375	2026-06-03	Buy

Product number	Packaging	Price	Buy
31405	25mg	$90	Buy
31405	50mg	$158	Buy
31405	100mg	$297	Buy
31405	500mg	$783	Buy
295736	250mg	$375	Buy

2,6-Dichloropurine riboside Chemical Properties, Uses, Production

Chemical Properties

White to Off-White Solid

Uses

2,6-Dichloropurine-9-β-D-riboside is a useful reagent for the design of AB680 as potent and selective inhibitor of CD73.

Synthesis

9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE

3056-18-6

13276-52-3

Under nitrogen protection, 450 mL of fully acetyl-protected 2,6-dichloropurine riboside (0.1 mol) and anhydrous methanol were added to a three-necked flask equipped with a dropping funnel, stirred until the system was completely clarified, and cooled to -10°C. The reaction was carried out by TLC. Acetyl chloride (1.2 moles) was added slowly dropwise and after completion of the dropwise addition, the reaction was continued for 1.5 h. The progress of the reaction was monitored by TLC. After completion of the reaction, solid potassium carbonate was added to the system in batches until the pH reached 7-8 and the reaction mixture was filtered. The filtrate was concentrated to dryness, appropriate amount of water was added and extracted three times with 250 mL of ethyl acetate. The organic phases were combined, dried over anhydrous sodium sulfate, filtered and the filtrate concentrated to dryness. Crystallization was carried out by adding 140 mL of isopropanol to give 27.3 g of 2,6-dichloropurine riboside as a white solid in 85% yield.

References

[1] Patent: CN105085595, 2017, B. Location in patent: Paragraph 0015; 0016; 0017; 0018

2,6-Dichloropurine riboside Preparation Products And Raw materials

Raw materials

9-[2,3,5-Tri-O-acetyl-beta-D-ribofuranosyl]-2,6-dichloropurine 9H-Purine, 2,6-dichloro-9-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)- 9H-Purine, 6-chloro-2-nitro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)- Methanol Acetyl chloride

Preparation Products

2,6-Dichloropurine riboside Suppliers

Global Suppliers ( 275)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Hongene Biotech Corporation	021-64757213	info@hongene.com	China	672	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078	sales@jingyan-chemical.com	China	9963	60
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
INTATRADE GmbH	66
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Hongene Biotech Corporation	61
Capot Chemical Co., Ltd	66
JinYan Chemicals(ShangHai) Co.,Ltd.	60
Jia Xing Isenchem Co.,Ltd	66
Adamas Reagent, Ltd.	59
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky（shanghai）International Co.,Ltd.	50

Preparation of 2,6-Dichloropurine riboside
2,6-Dichloropurine riboside is an antitumor and antiviral drug, and is effective in the treatment of infections caused by myco....
Sep 21,2022

View Latest Price from 2,6-Dichloropurine riboside manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-17	2,6-Dichloropurine riboside 13276-52-3		1kg	98%min	1000kg	WUHAN FORTUNA CHEMICAL CO., LTD
2026-07-15	2,6-Dichloropurine-9-β-D-riboside 13276-52-3	$287.00-978.00			10g	TargetMol Chemicals Inc.
2025-12-16	Regadenoson Impurity 13276-52-3		10mg	99%+ HPLC	1000	Moxin Chemicals

2,6-Dichloropurine riboside
13276-52-3
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

2,6-Dichloropurine-9-β-D-riboside
13276-52-3
$287.00-978.00
TargetMol Chemicals Inc.

Regadenoson Impurity
13276-52-3
99%+ HPLC
Moxin Chemicals

13276-52-3 (2,6-Dichloropurine riboside) Related Search:

Guanosine 2,6-Dichloropurine 2,4-Dichlorobenzoic acid Carbon tetrachloride Dichloroethane

Xylene Purine β-Nicotinamide adenine dinucleotide 2,6-Dichloropurine-2'-deoxyriboside 6-Chloropurine ribonucleoside

RIBAVIRINA 6-Chloropurine-2'-deoxyriboside 6-Chloro-9-(5-deoxy-D-ribofuranosyl)purine 9-[2,3,5-Tri-O-acetyl-beta-D-ribofuranosyl]-2,6-dichloropurine 2,6-Dichloropurine riboside

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2, 6-DICHLOROPURINE RIBOSIDE (2,6DClPR) 2,6-Dichloropurine r 2,6-dichloro-9-(β-D-ribofuranosyl)purine 2,6-Dichloro-9-(beta-D-ribofuranosyl)purine 2,6-Dichloro-9-β-D-ribofuranosyl-9H-purine 2,6-dichloropuine nuceotide (2R,3R,4S,5R)-2-(2,6-Dichloro-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol 2,6-Dichloropurine riboside###13276-52-3 2,6-DICHLOROPURINE-9-BETA-D-RIBOSIDE 2,6-DICHLOROPURINE RIBOSIDE 2,6-Dichloropurine-9-b-D-riboside 105393 (2R,3R,4S,5R)-2-(2,6-dichloro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 2,6-DICHLOROPURINE RIBO 2,6-Dichloro-9-(b-D-ribofuranosyl)purine 2,6-Dichloropurine-9--D-riboside 2,6-Dichloropurine Ribose 9H-Purine, 2,6-dichloro-9-β-D-ribofuranosyl- 2,6-Dichloropurine-9-β-D-riboside 6-Dichloropurine riboside 2,6-Dichloropurine riboside USP/EP/BP (2R,3R,4S,5R)-2-(2,6-dichloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 2,6-Dichloro-9H-purine Riboside 2,6-Dichloropurine nucleoside 2,6-Dichloro-9-(β-D-ribofuranosyl)-9H-purine 2,6-Dichloro-9-(β-D-ribofuranosyl)purine Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxy-5-methyl-, 2′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] (ACI) 13276-52-3 C10H10Cl2N4O4 API intermediates Miscellaneous Biochemicals Bases & Related Reagents Nucleotides