Biotin-PEG4-Dde-TAMRA-PEG3-Azide
- CAS No.
- 2353409-56-8
- Chemical Name:
- Biotin-PEG4-Dde-TAMRA-PEG3-Azide
- Synonyms
- Dde TAMRA Biotin Azide;Dde TAMRA Biotin Azide Dde;Biotin-PEG4-Dde-TAMRA-PEG3-Azide
- CBNumber:
- CB08054674
- Molecular Formula:
- C69H97N12O17S
- Molecular Weight:
- 1398.65
- MDL Number:
- MFCD34470009
- MOL File:
- 2353409-56-8.mol
Biotin-PEG4-Dde-TAMRA-PEG3-Azide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| dPEG | CCT-1367-5 | Dde TAMRA Biotin Azide | 5mg | $584 | 2026-06-04 | Buy | |
| dPEG | CCT-1367-25 | Dde TAMRA Biotin Azide | 25mg | $1961 | 2026-06-04 | Buy | |
| dPEG | CCT-1367-1 | Dde TAMRA Biotin Azide | 1mg | $170 | 2026-06-04 | Buy | |
| aablocks | AA01JOSU | Biotin-PEG4-Dde-TAMRA-PEG3-Azide >96% | 2353409-56-8 | 25mg | $1831 | 2026-05-30 | Buy |
| aablocks | AA01JOSU | Biotin-PEG4-Dde-TAMRA-PEG3-Azide >96% | 2353409-56-8 | 100mg | $5045 | 2026-05-30 | Buy |
Biotin-PEG4-Dde-TAMRA-PEG3-Azide Chemical Properties, Uses, Production
Description
Dde TAMRA Biotin Azide is a trifunctional, cleavable probe that allows for efficient recovery of avidin-bound protein complexes in affinity-based assays. This reagent contains a fluorescent dye (TAMRA) and biotin moiety linked to azide group through a spacer arm containing a hydrazine-cleavable Dde moiety. Under mild conditions (2% aqueous hydrazine), the Dde liner is cleaved, releasing the biotin tag and any avidin conjugate bound to it.
Uses
Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
Cleavable Linker
References
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
Biotin-PEG4-Dde-TAMRA-PEG3-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
Biotin-PEG4-Dde-TAMRA-PEG3-Azide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Zhengzhou Acme Chemical Co., Ltd. | 037163312495 13303845143 | 1416159398@qq.com | China | 10150 | 58 |
| Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd. | 0755-23251735 13302967066 | sales@geneseqtools.com | China | 1466 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 2980 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Affinity Linkers Ltd. | 15841022315 15841022315 | sales@affinitytech.cn | China | 7039 | 58 |
| Shanghai meikai technology co., ltd | 021-68689288 15300790979 | info@mkbio.com.cn | China | 9755 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50089 | 58 |
