(Rac)-Benpyrine
- CAS No.
- 1333714-43-4
- Chemical Name:
- (Rac)-Benpyrine
- Synonyms
- (Rac)-Benpyrine;Benpyrine racemate;(Rac)-Benpyrine, 10 mM in DMSO;4-((9H-Purin-6-yl)amino)-1-benzylpyrrolidin-2-one;2-Pyrrolidinone, 1-(phenylmethyl)-4-(9H-purin-6-ylamino)-;autoimmune,Inhibitor,anti-inflammatory,(Rac) Benpyrine,(Rac)-Benpyrine,Tumor Necrosis Factor Receptor,IFN-γ,IL-1β,(Rac)Benpyrine,inhibit,TNF Receptor,IL-6,NF-κB,TNFR,TNF-α,IL-10
- CBNumber:
- CB08057640
- Molecular Formula:
- C16H16N6O
- Molecular Weight:
- 308.34
- MDL Number:
- MOL File:
- 1333714-43-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
(Rac)-Benpyrine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 36680 | rac-Benpyrine ≥98% | 1333714-43-4 | 1mg | $57 | 2026-04-30 | Buy |
| Cayman Chemical | 36680 | rac-Benpyrine ≥98% | 1333714-43-4 | 5mg | $238 | 2026-04-30 | Buy |
| Cayman Chemical | 36680 | rac-Benpyrine ≥98% | 1333714-43-4 | 10mg | $445 | 2026-04-30 | Buy |
| Biosynth | IDC71443 | (rac)-Benpyrine | 1333714-43-4 | 50mg | $828.5 | 2026-06-04 | Buy |
| Biosynth | IDC71443 | (rac)-Benpyrine | 1333714-43-4 | 100mg | $1326 | 2026-06-04 | Buy |
(Rac)-Benpyrine Chemical Properties,Uses,Production
Uses
(Rac)-Benpyrine, a racemate of Benpyrine, is a potent and orally active TNF-α inhibitor. (Rac)-Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research[1].
in vivo
(Rac)-Benpyrine (Compound 001; 25-50 mg/kg; oral gavage; daily; for 3 weeks; Kunming mice) treatment obviously reduces the inflammatory cytokines IFN-γ, IL-1β and IL-6 in the blood serum, and the anti-inflammatory factor IL-10 is obviously increased, the foot swelling degree of the arthritis part is also obviously slowed down, and the weight index increase caused by the arthritis also has no obvious reduction[1].
| Animal Model: | Kunming mice (7-8 weeks) treated with bovine type II collagen and a CFA complete adjuvant[1] |
| Dosage: | 25 mg/kg, 50 mg/kg |
| Administration: | Oral gavage; daily; for 3 weeks |
| Result: | The inflammatory cytokines IFN-γ, IL-1β and IL-6 in the blood serum were obviously reduced, and the anti-inflammatory factor IL-10 was obviously increased. |
References
[1] Hua Li, et al. Compound with TNF- α inhibitory activity and application. CN111320630A.
(Rac)-Benpyrine Preparation Products And Raw materials
Raw materials
Preparation Products
(Rac)-Benpyrine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4861 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9699 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
View Lastest Price from (Rac)-Benpyrine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | (Rac)-Benpyrine
1333714-43-4
|
$40.00-163.00 | 98.55% | 10g | TargetMol Chemicals Inc. |
-
- (Rac)-Benpyrine
1333714-43-4
- $40.00-163.00
- 98.55%
- TargetMol Chemicals Inc.
