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ChemicalBook >> CAS DataBase List >>1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester

1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester

1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester Structure
1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester structure
CAS No.
2454244-02-9
Chemical Name:
1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester
Synonyms
IRAK4-IN-6;1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester
CBNumber:
CB08186368
Molecular Formula:
C25H32N10O2
Molecular Weight:
504.59
MDL Number:
MOL File:
2454244-02-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:07
Request For Quotation

1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester Properties

Boiling point 741.4±70.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 125 mg/mL (247.73 mM)
pka 7.18±0.70(Predicted)
form Powder
color Light yellow to yellow

1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0106052 IRAK4-IN-6 99.30% 2454244-02-9 5mg $542 2026-06-04 Buy
ChemScene CS-0106052 IRAK4-IN-6 99.30% 2454244-02-9 10mg $921 2026-06-04 Buy
ChemScene CS-0106052 IRAK4-IN-6 99.30% 2454244-02-9 25mg $1950 2026-06-04 Buy
ChemScene CS-0106052 IRAK4-IN-6 99.30% 2454244-02-9 50mg $3250 2026-06-04 Buy
ChemScene CS-0106052 IRAK4-IN-6 99.30% 2454244-02-9 100mg $4983 2026-06-04 Buy
Product number Packaging Price Buy
CS-0106052 5mg $542 Buy
CS-0106052 10mg $921 Buy
CS-0106052 25mg $1950 Buy
CS-0106052 50mg $3250 Buy
CS-0106052 100mg $4983 Buy

1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester Chemical Properties, Uses, Production

Uses

IRAK4-IN-6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma[1].

References

[1] Degorce SL, et al. Discovery of a Series of 5-Azaquinazolines as Orally Efficacious IRAK4 Inhibitors TargetingMyD88L265P Mutant Diffuse Large B Cell Lymphoma. J Med Chem. 2019 Nov 1. DOI:10.1021/acs.jmedchem.9b01346

1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester Suppliers

Global Suppliers ( 6)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9831 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Aladdin Scientific tp@aladdinsci.com United States 50068 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
RD International Technology Co., Limited 58
TargetMol Chemicals Inc. 58
Aladdin Scientific 58

2454244-02-9 (1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester) Related Search:

LCC-12 (formate) FMF-06-098-1 Anti-cancer compound library IRAK4-IN-1 2-Pyridinecarboxamide, 6-(1,1-difluoroethyl)-N-[2-[trans-4-[[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-7-azaspiro[3.5]non-7-yl]methyl]cyclohexyl]-6-methoxy-2H-indazol-5-yl]-
N-[2-[trans-4-[[6-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-2-azaspiro[3.3]hept-2-yl]methyl]cyclohexyl]-5-(1-hydroxy-1-methylethyl)-6-benzothiazolyl]-6-(trifluoromethyl)-2-pyridinecarboxamide

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1-Piperazinecarboxylic acid, 4-[trans-4-[[6-(cyanomethyl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-, methyl ester IRAK4-IN-6 2454244-02-9 C25H32N10O2