ChemicalBook >> CAS DataBase List >>IRAK4-IN-1
IRAK4-IN-1
- CAS No.
- 1820787-94-7
- Chemical Name:
- IRAK4-IN-1
- Synonyms
- IRAK4-IN-1;IRAK4-IN-1, >98%;IRAK4 inhibitor 1;IRAK4-IN-1 ，S0008;4-((trans-4-Morpholinocyclohexyl)amino)quinazoline-6-carbonitrile;6-Quinazolinecarbonitrile, 4-[[trans-4-(4-morpholinyl)cyclohexyl]amino]-;inhibit,IRAK4 IN 1,Inhibitor,IL-1R associated kinase,Interleukin-1 receptor associated kinase,IRAK4IN1,IRAK-4-IN-1,IRAK
- CBNumber:
- CB13355317
- Molecular Formula:
- C19H23N5O
- Molecular Weight:
- 337.42
- MDL Number:
- MFCD31620830
- MOL File:
- 1820787-94-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-14 16:49:18
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
IRAK4-IN-1 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 37548 | IRAK4 Inhibitor 1 ≥98% | 1820787-94-7 | 1mg | $63 | 2026-04-30 | Buy |
| Cayman Chemical | 37548 | IRAK4 Inhibitor 1 ≥98% | 1820787-94-7 | 5mg | $248 | 2026-04-30 | Buy |
| Cayman Chemical | 37548 | IRAK4 Inhibitor 1 ≥98% | 1820787-94-7 | 10mg | $403 | 2026-04-30 | Buy |
| Cayman Chemical | 37548 | IRAK4 Inhibitor 1 ≥98% | 1820787-94-7 | 25mg | $850 | 2026-04-30 | Buy |
| Biosynth | VXC78794 | IRAK4-IN-1 | 1820787-94-7 | 50mg | $590 | 2026-06-05 | Buy |
IRAK4-IN-1 Chemical Properties, Uses, Production
Uses
IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.
in vivo
Oral pharmacokinetic studies of IRAK4-IN-1 (Compound 23) show it to have high bioavailability of 73% and low plasma clearance (Clp=22 mL/min/kg) leading to a reasonable half-life of 1.3 h[1].
References
[1] Smith GF, et al. Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2721-2726. DOI:10.1016/j.bmcl.2017.04.050
IRAK4-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 51)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai JiYi Biotechnology Co. Ltd. | 13621943973 | sales@shjiyipharmatech.com | China | 1166 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Medi-tech Bioscientific Co., Ltd. | 0519-83246372 13585352506 | China | 1838 | 58 | |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3307 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
View Latest Price from IRAK4-IN-1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | IRAK4-IN-1
1820787-94-7
|
$64.00-239.00 | 99.85% | 10g | TargetMol Chemicals Inc. |
-
- IRAK4-IN-1
1820787-94-7
- $64.00-239.00
- 99.85%
- TargetMol Chemicals Inc.
IRAK4-IN-1
IRAK4-IN-1, >98%
IRAK4 inhibitor 1
6-Quinazolinecarbonitrile, 4-[[trans-4-(4-morpholinyl)cyclohexyl]amino]-
inhibit,IRAK4 IN 1,Inhibitor,IL-1R associated kinase,Interleukin-1 receptor associated kinase,IRAK4IN1,IRAK-4-IN-1,IRAK
4-((trans-4-Morpholinocyclohexyl)amino)quinazoline-6-carbonitrile
IRAK4-IN-1 ，S0008
1820787-94-7
