ChemicalBook >> CAS DataBase List >>IRAK4-IN-1

IRAK4-IN-1

IRAK4-IN-1 structure

CAS No.: 1820787-94-7

Chemical Name:: IRAK4-IN-1

Synonyms: IRAK4-IN-1;IRAK4-IN-1, >98%;IRAK4 inhibitor 1;4-((trans-4-Morpholinocyclohexyl)amino)quinazoline-6-carbonitrile;6-Quinazolinecarbonitrile, 4-[[trans-4-(4-morpholinyl)cyclohexyl]amino]-;inhibit,IRAK4 IN 1,Inhibitor,IL-1R associated kinase,Interleukin-1 receptor associated kinase,IRAK4IN1,IRAK-4-IN-1,IRAK

CBNumber:: CB13355317

Molecular Formula:: C19H23N5O

Molecular Weight:: 337.42

MDL Number:: MFCD31620830

MOL File:: 1820787-94-7.mol

Last updated:2025-04-30 13:36:08

Request For Quotation

IRAK4-IN-1 Properties

Boiling point	548.9±50.0 °C(Predicted)
Density	1.26±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 14.29 mg/mL (42.35 mM);Water : < 0.1 mg/mL (insoluble)
form	Solid
pka	7.81±0.20(Predicted)
color	White to off-white

IRAK4-IN-1 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-7925	IRAK4-IN-1 ≥99.0%	1820787-94-7	1mg	$180	2021-12-16	Buy
ChemScene	CS-7925	IRAK4-IN-1 ≥99.0%	1820787-94-7	5mg	$540	2021-12-16	Buy
ChemScene	CS-7925	IRAK4-IN-1 ≥99.0%	1820787-94-7	10mg	$900	2021-12-16	Buy
ChemScene	CS-7925	IRAK4-IN-1 ≥99.0%	1820787-94-7	25mg	$1800	2021-12-16	Buy
ChemScene	CS-7925	IRAK4-IN-1 ≥99.0%	1820787-94-7	50mg	$2640	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-7925	1mg	$180	Buy
CS-7925	5mg	$540	Buy
CS-7925	10mg	$900	Buy
CS-7925	25mg	$1800	Buy
CS-7925	50mg	$2640	Buy

IRAK4-IN-1 Chemical Properties,Uses,Production

Uses

IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.

in vivo

Oral pharmacokinetic studies of IRAK4-IN-1 (Compound 23) show it to have high bioavailability of 73% and low plasma clearance (Clp=22 mL/min/kg) leading to a reasonable half-life of 1.3 h^[1].

References

[1] Smith GF, et al. Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2721-2726. DOI:10.1016/j.bmcl.2017.04.050

IRAK4-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

IRAK4-IN-1 Suppliers

Global( 46)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32268	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38663	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Shanghai JiYi Biotechnology Co. Ltd.	13621943973	sales@shjiyipharmatech.com	China	1166	55
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847; 18021002903	3008007409@qq.com	China	71826	60

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
TargetMol Chemicals Inc.	58
InvivoChem	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Shanghai JiYi Biotechnology Co. Ltd.	55
Shanghai YuanYe Biotechnology Co., Ltd.	60

View Lastest Price from IRAK4-IN-1 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-04-30	IRAK4-IN-1 1820787-94-7	US $64.00-239.00 / mg		98.18%	10g	TargetMol Chemicals Inc.

IRAK4-IN-1
1820787-94-7
US $64.00-239.00 / mg
98.18%
TargetMol Chemicals Inc.

IRAK4-IN-1 IRAK4-IN-1, >98% IRAK4 inhibitor 1 6-Quinazolinecarbonitrile, 4-[[trans-4-(4-morpholinyl)cyclohexyl]amino]- inhibit,IRAK4 IN 1,Inhibitor,IL-1R associated kinase,Interleukin-1 receptor associated kinase,IRAK4IN1,IRAK-4-IN-1,IRAK 4-((trans-4-Morpholinocyclohexyl)amino)quinazoline-6-carbonitrile 1820787-94-7