ChemicalBook >> CAS DataBase List >>ZED-1227
ZED-1227
- CAS No.
- 1542132-88-6
- Chemical Name:
- ZED-1227
- Synonyms
- ZED-1227;ZED 1227,ZED1227;Methyl (S,E)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-2-oxo-1,2-dihydropyridin-3-yl)amino)-6-(1-methyl-1H-imidazole-5-carboxamido)-7-oxohept-2-enoate;2-Heptenoic acid, 7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1H-imidazol-5-yl)carbonyl]amino]-7-oxo-, methyl ester, (2E,6S)-
- CBNumber:
- CB08190819
- Molecular Formula:
- C26H36N6O6
- Molecular Weight:
- 528.6
- MDL Number:
- MFCD30532544
- MOL File:
- 1542132-88-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 22:54:10
| Product description | Number | Pack Size | Price |
| ZED-1227 ≥95% | 42333 | 500μg | $109 |
| ZED-1227 ≥95% | 42333 | 1mg | $196 |
| ZED-1227 ≥95% | 42333 | 5mg | $818 |
| ZED-1227 ≥95% | 42333 | 10mg | $1307 |
| Vilagletistat 99.82% | CS-0015432 | 1mg | $379 |
| Boiling point | 916.3±65.0 °C(Predicted) |
|---|---|
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | 10.63±0.20(Predicted) |
| color | Off-white to light yellow |
| FDA UNII | T4SR539YKF |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
ZED-1227 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 42333 | ZED-1227 ≥95% | 1542132-88-6 | 500μg | $109 | 2026-04-30 | Buy |
| Cayman Chemical | 42333 | ZED-1227 ≥95% | 1542132-88-6 | 1mg | $196 | 2026-04-30 | Buy |
| Cayman Chemical | 42333 | ZED-1227 ≥95% | 1542132-88-6 | 5mg | $818 | 2026-04-30 | Buy |
| Cayman Chemical | 42333 | ZED-1227 ≥95% | 1542132-88-6 | 10mg | $1307 | 2026-04-30 | Buy |
| ChemScene | CS-0015432 | Vilagletistat 99.82% | 1542132-88-6 | 1mg | $379 | 2026-06-04 | Buy |
ZED-1227 Chemical Properties,Uses,Production
Uses
(2E,6S)-7-[[1-[2-[(2-Ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1H-imidazol-5-yl)carbonyl]amino]-7-oxo-2-heptenoic Acid Methyl Ester is a derivative of pyridinone which serves as transglutaminase inhibitors.
in vivo
ZED-1227 reduces the activity of intestinal TG2 induced by Polyinosinic:Polycytidylic acid (40 mg/kg) to normal control levels and subdues intestinal inflammation in mice[1].
ZED-1227 (5 mg/kg; i.g.) is able to inhibit TG2 in the small intestinal mucosa[2].
| Animal Model: | BALB/c mice[2] |
| Dosage: | 5 mg/kg |
| Administration: | Oral gavage |
| Result: | Inhibited TG2 in vivo in the small intestinal mucosa. |
ZED-1227 Preparation Products And Raw materials
Raw materials
Preparation Products
ZED-1227 Suppliers
Global( 20)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Biolang biotechnology Co.,Ltd | 17764003753 | 2326587775@qq.com | China | 185 | 55 |
| Shanghai Biolang biotechnology Co.,Ltd | 17764003753 | 2326587775@qq.com | China | 185 | 55 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Hubei Weideli Chemical Reagent Co., Ltd. | 15871722230 | 15871722230@163.com | China | 4465 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44924 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2936 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5987 | 58 |
1542132-88-6(ZED-1227)Related Search:
1of2
2-Heptenoic acid, 7-[[1-[2-[(2-ethylbutyl)amino]-2-oxoethyl]-1,2-dihydro-2-oxo-3-pyridinyl]amino]-6-[[(1-methyl-1H-imidazol-5-yl)carbonyl]amino]-7-oxo-, methyl ester, (2E,6S)-
ZED-1227
ZED 1227,ZED1227
Methyl (S,E)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-2-oxo-1,2-dihydropyridin-3-yl)amino)-6-(1-methyl-1H-imidazole-5-carboxamido)-7-oxohept-2-enoate
1542132-88-6






