3-Heptanone
- CAS No.
- 106-35-4
- Chemical Name:
- 3-Heptanone
- Synonyms
- HEPTAN-3-ONE;ETHYL BUTYL KETONE;FEMA 2545;3-Heptanon;heptane-3-one;Butyl Ethanone;n-Heptan-3-one;heptan-3-;Heptan-3-on;3-HEPTANONE
- CBNumber:
- CB0852672
- Molecular Formula:
- C7H14O
- Molecular Weight:
- 114.19
- MDL Number:
- MFCD00009483
- MOL File:
- 106-35-4.mol
- MSDS File:
- SDS
| Melting point | -39 °C (lit.) |
|---|---|
| Boiling point | 146-149 °C (lit.) |
| Density | 0.818 g/mL at 25 °C (lit.) |
| vapor pressure | 1.4 at 25 °C (quoted, Verschueren, 1983) |
| FEMA | 2545 | 3-HEPTANONE |
| refractive index |
n |
| FLAVIS Number | 07.003 | Heptan-3-one |
| Flash point | 106 °F |
| storage temp. | Flammables area |
| solubility | 4.3g/l |
| form | Liquid |
| color | Clear slightly yellow |
| Odor | at 1.00 % in dipropylene glycol. powerful green fatty fruity |
| Odor Type | green |
| biological source | synthetic |
| Water Solubility | 3.3 g/L (20 ºC) |
| Thermal Conductivity | 0.137 W/(m·K) at 25 ℃ |
| JECFA Number | 285 |
| BRN | 506161 |
| Henry's Law Constant | 4.38 x 10-4(atmm3/mol) at 37 °C (static headspace-GC, Bylaite et al., 2004) |
| Exposure limits |
ACGIH:TLV-TWA 10 ppm OSHA:PEL-TWA 50 ppm (230 mg/m3) NIOSH:REL-TWA 50 ppm |
| Dielectric constant | 12.9(22℃) |
| Stability | Stable. Flammable. Incompatible with strong oxidizing agents, strong bases, strong reducing agents. May form peroxides in storage if in contact with air - store under inert gas. |
| Cosmetics Ingredients Functions | PERFUMING |
| InChI | 1S/C7H14O/c1-3-5-6-7(8)4-2/h3-6H2,1-2H3 |
| InChIKey | NGAZZOYFWWSOGK-UHFFFAOYSA-N |
| SMILES | CCCCC(=O)CC |
| LogP | 1.97 |
| CAS DataBase Reference | 106-35-4(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | 3-HEPTANONE |
| EWG's Food Scores | 1 |
| FDA UNII | 10GA6SR3AT |
| NIST Chemistry Reference | 3-Heptanone(106-35-4) |
| EPA Substance Registry System | 3-Heptanone (106-35-4) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H332-H303-H315-H319-H335-H336-H305-H226 | |||||||||
| Precautionary statements | P501-P240-P261-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P312-P331-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P301+P310-P304+P340+P312-P403+P233-P403+P235-P405 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-38-40-48/20/22-36-20-10 | |||||||||
| Safety Statements | 36-24-36/37-24/25 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| OEB | A | |||||||||
| OEL | TWA: 50 ppm (230 mg/m3) | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | MJ5250000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29141990 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Inhalation Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2 |
|||||||||
| Hazardous Substances Data | 106-35-4(Hazardous Substances Data) | |||||||||
| Toxicity | Acute oral LD50 for rats 2,760 mg/kg (quoted, RTECS, 1985). | |||||||||
| IDLA | 1,000 ppm | |||||||||
| NFPA 704 |
|
3-Heptanone price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W254509 | 3-Heptanone 96% | 106-35-4 | 1 each | $58 | 2026-04-30 | Buy |
| Sigma-Aldrich | W254509 | 3-Heptanone 96% | 106-35-4 | 1kg | $691 | 2026-04-30 | Buy |
| Sigma-Aldrich | 90046 | 3-Heptanone analytical standard | 106-35-4 | 1ml | $96.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | W254509 | 3-Heptanone 96% | 106-35-4 | 1 unit | $53.48 | 2025-07-31 | Buy |
| Sigma-Aldrich | 551325 | 3-Heptanone solution NMR reference standard, 1% in chloroform-d (99.8 atom % D), NMR tube size 5?mm × 8?in. | 106-35-4 | 1EA | $194 | 2022-05-15 | Buy |
3-Heptanone Chemical Properties, Uses, Production
Description
3-Heptanone has a powerful, green, fatty, fruity odor and a melon, banana flavor. Prepared from n-hept-2-one by hydration.
Chemical Properties
3-Heptanone has a fruity, green, fatty, sweet, ethereal, powerful odor and a melon, banana favor.
Chemical Properties
colourless liquid
Chemical Properties
Ethyl butyl ketone is a colorless liquid with a powerful, fruity odor.
Occurrence
Reported found in apple juice, banana, peach, pear, spearmint oil, Parmesan cheese, butter, cream, lean fsh, fsh oil, roasted chicken, cooked beef, coffee, peanut oil, pecan, yellow passion fruit, plumcot, beans, plum brandy, sesame seed, mango and cooked shrimps
Uses
Ethyl butyl ketone is used as a solvent fornitrocellulose and polyvinyl resins, and as anintermediate in organic synthesis.
Uses
Solvent and intermediate for organic materials
Uses
3-Heptanone is a seven carbon ketone with a "fruity" scent. It is often used as a perfume/fragrance industry and can also be applied as a solvent.
Uses
Solvent mix for air-dried and baked finishes, for polyvinyl and nitrocellulose resins.
Definition
ChEBI: A dialkyl ketone with butyl and ethyl as the two alkyl groups.
Preparation
From n-hept-2-one by hydration.
Production Methods
EnBK is produced either by catalytic dehydrogenation of 3-heptanol or by hydrogenation of the mixed alcohol condensation product of propionaldehyde and methyl ethyl ketone. Commercial samples can be 95% pure.
Aroma threshold values
Detection: 7 5 to 160 ppb.
Taste threshold values
Taste characteristics at 50 ppm: ketonic, with a cheese-like creamy character.
Synthesis Reference(s)
Journal of the American Chemical Society, 94, p. 1788, 1972 DOI: 10.1021/ja00760a084
Tetrahedron Letters, 23, p. 2379, 1982 DOI: 10.1016/S0040-4039(00)87347-5
Synthetic Communications, 22, p. 1589, 1992 DOI: 10.1080/00397919208021632
General Description
Colorless odorless liquid with a mild fruity odor. Flash point 140°F.
Air & Water Reactions
Flammable.
Reactivity Profile
3-Heptanone is reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion. Reacts with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. May react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4. Irritating vapors and toxic gases may be formed when involved in fire [USCG, 1999].
Hazard
Moderate fire risk.
Health Hazard
Short term exposure can cause irritation of eyes, nose, throat and lungs. High concentrations may cause headache, dizziness or unconsciousness.
Health Hazard
Inhalation of the vapor of ethyl butyl ketonecan cause irritation to the eyes, skin, andmucous membranes. Its irritation effect wasmild on rabbit skin and eyes. Prolonged skincontact can cause dermatitis. Exposure to4000 ppm for 4 hours proved fatal to rats.Ingestion can cause headache and narcosis,and in large doses coma can occur.
LD50 value, oral (rats): 2760 mg/kg.
Fire Hazard
Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as carbon dioxide and carbon monoxide, may be formed when involved in fire.
Safety Profile
Moderately toxic by ingestion and inhalation. A skin and eye irritant. A flammable liquid. Can react with oxidizing materials. To fight fire, use foam, Co2, dry chemical. See also KETONES.
Potential Exposure
Ethyl butyl ketone is used as a solvent and as an intermediate in organic synthesis. It is a solvent for vinyl and nitrocellulose resins. It is used in food flavoring
First aid
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit
Environmental Fate
Chemical/Physical. 3-Heptanone will not hydrolyze because it has no hydrolyzable functional group.
Solubility in organics
Insoluble in water, soluble in alcohol, miscible with oils.
storage
Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with this chemical you should be trained onits proper handling and storage. Ethyl butyl ketone must bestored to avoid contact with oxidizers, such as peroxides,chlorates, perchlorates, permanganates, and nitrates, becauseviolent reactions occur. Store in tightly closed containers ina cool, well-ventilated area away from heat. Sources of ignition, such as smoking and open flames, are prohibited whereethyl butyl ketone is used, handled, or stored in a mannerthat could create a potential fire or explosion hazard
Shipping
UN1224 Ketones, liquid, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid, Technical Name Required.
Incompatibilities
May form explosive mixture with air. Violent reaction with strong oxidizers, acetaldehyde, perchloric acid. Attacks some plastics, rubber and coatings
Waste Disposal
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed
3-Heptanone Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Xinyang Ruihe Chemical Technology Co., Ltd. | 13720181483 13720181483 | 366443693@QQ.COM | China | 994 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 |
View Latest Price from 3-Heptanone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 3-Heptanone
106-35-4
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2021-08-12 | 3-Heptanone
106-35-4
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2020-02-26 | 3-Heptanone
106-35-4
|
100g | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 3-Heptanone
106-35-4
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-Heptanone
106-35-4
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-Heptanone
106-35-4
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
