Cyclopentadecanone
- CAS No.
- 502-72-7
- Chemical Name:
- Cyclopentadecanone
- Synonyms
- EXALTONE;MUSK 15;exalton;Normuscon;NORMUSCONE;CYCLOPENTADECONE;Cyclopentadecanon;CYCLOPENTADECANONE;CYCLOPENTANDECANONE;Exaltone~Normuscone
- CBNumber:
- CB2416348
- Molecular Formula:
- C15H28O
- Molecular Weight:
- 224.38
- MDL Number:
- MFCD00001266
- MOL File:
- 502-72-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 63-65 °C (lit.) |
|---|---|
| Boiling point | 120 °C/0.3 mmHg (lit.) |
| Density | 0.897 g/mL at 25 °C (lit.) |
| vapor pressure | 0.009Pa at 40℃ |
| refractive index | 1.4637 (estimate) |
| Flash point | 120°C/0.3mm |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Alcohol |
| form | powder to crystal |
| color | Colourless crystal needles. |
| Odor | at 10.00 % in dipropylene glycol. powdery musk animal natural greasy |
| Odor Type | musk |
| Water Solubility | 578μg/L at 20℃ |
| BRN | 1618444 |
| Cosmetics Ingredients Functions |
DEODORANT FRAGRANCE |
| InChI | 1S/C15H28O/c16-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-15/h1-14H2 |
| InChIKey | OSOIQJGOYGSIMF-UHFFFAOYSA-N |
| SMILES | O=C1CCCCCCCCCCCCCC1 |
| LogP | 5.6 at 20℃ |
| CAS DataBase Reference | 502-72-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | T09G246LET |
| NIST Chemistry Reference | Cyclopentadecanone(502-72-7) |
| EPA Substance Registry System | Cyclopentadecanone (502-72-7) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | GY0900000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29142900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Cyclopentadecanone price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C111201 | Cyclopentadecanone 98% | 502-72-7 | 5g | $55.5 | 2026-04-30 | Buy |
| TCI Chemical | C1422 | Cyclopentadecanone >98.0%(GC) | 502-72-7 | 5g | $41 | 2026-04-30 | Buy |
| TCI Chemical | C1422 | Cyclopentadecanone >98.0%(GC) | 502-72-7 | 25g | $162 | 2026-04-30 | Buy |
| Matrix Scientific | 099712 | Cyclopentadecanone | 502-72-7 | 5.00g | $57 | 2026-05-18 | Buy |
| Matrix Scientific | 099712 | Cyclopentadecanone | 502-72-7 | 10.00g | $84 | 2026-05-18 | Buy |
Cyclopentadecanone Chemical Properties,Uses,Production
Chemical Properties
WHITE CRYSTALLINE POWDER
Chemical Properties
Cyclopentadecanone is a musk fragrance found in the
scent gland of the male civet cat.
A number of syntheses have been developed for its manufacture [260]. Among
these, the so-called Story procedure is the only route that has the potential to
make cyclopentadecanone available on a larger scale, but due to the handling of
hydroperoxides, the process is difficult to manage.
The process starts from tricyclohexylidene triperoxide, which is obtained by
oxidation of cyclohexanone with hydrogen peroxide. Pyrolysis leads to a mixture
of 1,16-hexadecanolide and cyclopentadecane. The latter is oxidized by oxygen
under boric acid catalysis to cyclopentadecanol, which is subsequently oxidized
to cyclopentadecanone.
Due to the availability of long-chained aliphatic dicarboxylic acids by biotechnological
processes, a Dieckmann condensation reaction may also possibly
be a useful route to produce this macrocyclic ketone.
Cyclopentadecanone is used in fine fragrances：
Occurrence
Reported to be found in the scent glands of the Louisiana muskrat Ondatra zibethicus rivalicius (Guenther, 1949).
Uses
Cyclopentadecanone is the main odoriferous component of musk.
Preparation
By the cyclization of dinitriles in high dilution (Bedoukian. 1967).
Synthesis Reference(s)
Chemistry Letters, 7, p. 1283, 1978
The Journal of Organic Chemistry, 36, p. 3266, 1971 DOI: 10.1021/jo00821a003
Toxicity evaluation
Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg (Moreno. 1975). The acute ip LD100 of cyclopentadecanone was not reached but was estimated to be >35mmol/kg for mice; an ip dose of 11-25 mmol/kg caused no deaths in 24 hr and one of 8-92 mmol/kg caused no deaths in 4 days (the length of the study). An oral dose of ≥45 mmol/kg caused no deaths in mice. Intense agitation accompanied by catatonia of the tail was caused by low doses of cyclopentadecanone; gross examination of the mice revealed no specific pathology but occasionally degenerative hepatitis, proximal tubular nephritis and, rarely, pancreatic necrosis were found following dosing with cycloalkanones (Caujolle & Caujolle, 1965).
Flammability and Explosibility
Non flammable
Metabolism
Ketones are not readily metabolized, although most of them probably undergo appreciable reduction to the corresponding secondary alcohols, which are excreted in the urine as glucuronic acid conjugates (Williams, 1959). Cyclopentadecanone was hydroxylated in cultures of four steroid-hydroxylating fungi (Calonectria decora, Rhizopus nigricans, Daedalea rufescens and Ophiobolus herpotrichus), but was not affected by Aspergillus ochraceus. Initial attack occurred at the most remote carbon atom, with yields of up to 26% of 8-hydroxycyclopentadecanone, plus dihydroxy compounds and more polar products (Ashton, Bailey & Jones, 1974).
Purification Methods
Subliming Exaltone is better than crystallising it from aqueous EtOH for purification. The semicarbazone has m 186-187o. [Stevens & Erickson J Am Chem Soc 64 146 1942, Mathur et al. J Chem Soc 3505 1963, Biens & Hess Helv Chim Acta 71 1704 1988, Beilstein 7 III 203, 7 IV 118.]
Cyclopentadecanone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| shanghai hehua chemical co.,ltd | 15121167815 | bangge121@sina.com | China | 260 | 58 |
| Nanjing Optimal New Materials Technology Co., Ltd. | 180-86404407 17340521416 | 1757224788@qq.com | China | 1011 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Beckmann-Kenko GmbH | +49 4241 9308 88 | info@beckmann-kenko.com | Germany | 478 | 62 |
Related articles
- Structural Properties and Application of Cyclopentadecanone
- Cyclopentadecanone has also been prepared using synthetic routes starting from thiophene or cyclododecanone.
- Aug 31,2026
View Lastest Price from Cyclopentadecanone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-17 | Cyclopentadecanone
502-72-7
|
$56.00-113.00 | 97.09% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-06-30 | Cyclopentadecanone
502-72-7
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-03-20 | Cyclopentadecanone
502-72-7
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Cyclopentadecanone
502-72-7
- $56.00-113.00
- 97.09%
- TargetMol Chemicals Inc.
-
- Cyclopentadecanone
502-72-7
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- Cyclopentadecanone
502-72-7
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
