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Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate

CAS No.
112889-02-8
Chemical Name:
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
Synonyms
Raltitrexed F;Raltitrexed Impurity 24;diethyl n-[5-methylamino-2-thenoyl]-l-glutamate;Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP;(S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate;n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester;iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate;L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester
CBNumber:
CB0855299
Molecular Formula:
C15H22N2O5S
Molecular Weight:
342.41
MDL Number:
MFCD09750956
MOL File:
112889-02-8.mol
MSDS File:
SDS
Last updated:2025-07-16 09:54:04

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Properties

Boiling point 519.6±50.0 °C(Predicted)
Density 1.231
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 12.89±0.46(Predicted)
Appearance Brown to reddish brown Oil
InChI InChI=1S/C15H22N2O5S/c1-4-21-13(18)9-6-10(15(20)22-5-2)17-14(19)11-7-8-12(16-3)23-11/h7-8,10,16H,4-6,9H2,1-3H3,(H,17,19)/t10-/m0/s1
InChIKey OIUDYHGOODXYDK-JTQLQIEISA-N
SMILES C(OCC)(=O)[C@H](CCC(OCC)=O)NC(C1SC(NC)=CC=1)=O

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 304704 (S)-Diethyl 2-(5-(methylamino)thiophene-2-carboxamido)pentanedioate 112889-02-8 250.00mg $67 2026-05-19 Buy
Matrix Scientific 304704 (S)-Diethyl 2-(5-(methylamino)thiophene-2-carboxamido)pentanedioate 112889-02-8 1.00g $74 2026-05-19 Buy
Matrix Scientific 304704 (S)-Diethyl 2-(5-(methylamino)thiophene-2-carboxamido)pentanedioate 112889-02-8 5.00g $350 2026-05-19 Buy
aablocks AA0078N0 (S)-Diethyl 2-(5-(Methylamino)Thiophene-2-Carboxamido)Pentanedioate 95% 112889-02-8 1g $68 2026-05-28 Buy
aablocks AA0078N0 (S)-Diethyl 2-(5-(Methylamino)Thiophene-2-Carboxamido)Pentanedioate 95% 112889-02-8 5g $313 2026-05-28 Buy
Product number Packaging Price Buy
304704 250.00mg $67 Buy
304704 1.00g $74 Buy
304704 5.00g $350 Buy
AA0078N0 1g $68 Buy
AA0078N0 5g $313 Buy

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Chemical Properties, Uses, Production

Uses

N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Preparation Products And Raw materials

Global Suppliers ( 59)
Supplier Tel Email Country ProdList Advantage
Nanjing hongshenghuo Biotechnology Co., Ltd 025-58311670 18020159086 54604129@qq.com China 185 58
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Rochi Pharmaceutical Co., Ltd. 021-38751876 15000076078 Info@rochipharma.com China 616 55
Shanghai QianYan Bio-technology Co., Ltd 02781293128 orders@biochemsafebuy.com China 9904 55
Aikon International Limited 025-58859352 15955137747 sales01@aikonchem.com China 16021 58
Wuhan FengyaoTonghui Chemical Products Co., Ltd. 027-87466105 15377573527 2678564200@qq.com China 17968 58
Henan Alfachem Co.,Ltd. 0371-55051623 18137891487 3983243027@qq.com China 9974 58
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418684 +86-18949823763 sales@tnjchem.com China 25333 58
Nextpeptide Inc +86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19904 58
Dayang Chem (Hangzhou) Co.,Ltd. +86-0571-88938639 17705817739 info@dycnchem.com China 52451 58

View Latest Price from Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-Diethyl 2-(5-(methylamino)thiophene-2-carboxamido)pentanedioate pictures 2024-11-26 (S)-Diethyl 2-(5-(methylamino)thiophene-2-carboxamido)pentanedioate
112889-02-8
1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate pictures 2020-11-16 Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
112889-02-8
$120.00 1Kg/Bag 99 999 Longyan Tianhua Biological Technology Co., Ltd
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate pictures 2020-11-16 Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
112889-02-8
$120.00 1Kg/Bag 99 999 Longyan Tianhua Biological Technology Co., Ltd
n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester diethyl n-[5-methylamino-2-thenoyl]-l-glutamate (S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP Raltitrexed Impurity 24 Raltitrexed F 112889-02-8 Raltitrexed