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Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate

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Products Intro: Product Name:Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
CAS:112889-02-8
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Products Intro: Product Name:diethyl n-(5-methylamino-2-thenoyl)-l-glutamate
CAS:112889-02-8
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Products Intro: Product Name:Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
CAS:112889-02-8
Purity:99 Package:1Kg/Bag;120USD
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Products Intro: Product Name:(S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate
CAS:112889-02-8
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Products Intro: Product Name:Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
CAS:112889-02-8
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate manufacturers
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Basic information
Product Name:Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
Synonyms:n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester;diethyl n-[5-methylamino-2-thenoyl]-l-glutamate;(S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate;L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester;iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate;Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP;Raltitrexed Impurity 24;Raltitrexed F
CAS:112889-02-8
MF:C15H22N2O5S
MW:342.41
EINECS:
Product Categories:Raltitrexed
Mol File:112889-02-8.mol
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Structure
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Chemical Properties
Boiling point 519.6±50.0 °C(Predicted)
density 1.231
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka12.89±0.46(Predicted)
AppearanceBrown to reddish brown Oil
InChIInChI=1S/C15H22N2O5S/c1-4-21-13(18)9-6-10(15(20)22-5-2)17-14(19)11-7-8-12(16-3)23-11/h7-8,10,16H,4-6,9H2,1-3H3,(H,17,19)/t10-/m0/s1
InChIKeyOIUDYHGOODXYDK-JTQLQIEISA-N
SMILESC(OCC)(=O)[C@H](CCC(OCC)=O)NC(C1SC(NC)=CC=1)=O
Safety Information
MSDS Information
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Usage And Synthesis
UsesN-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Preparation Products And Raw materials
Preparation ProductsDiethyl N-[5-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N-methylamino]-2-thenoyl]-L-glutamate
Tag:Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate(112889-02-8) Related Product Information
ETHYL 3-AMINOCROTONATE Mefenpyr-diethyl Urethane Benzocaine P-AMINOBENZAMIDE GLUTAMIC ACID CARBONYL SULFIDE PYRAZOPHOS Diethyl oxalate 2-AMINODIETHYLMALONATE L-Glutamic acid Ethylene glycol diethyl ether Diethyl malonate Glutamic acid Celiprolol Diethyl ether ETHYL 2-[(2-THIENYLCARBONYL)AMINO]ACETATE N-ACETYL-L-GLUTAMIC ACID DIETHYL ESTER Glutamate