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p-(phenylthio)benzyl alcohol

CAS No.
6317-56-2
Chemical Name:
p-(phenylthio)benzyl alcohol
Synonyms
NSC 43060;(4-(Phenylthio);Einecs 228-658-6;p-(phenylthio)benzyl alcohol;4-(Phenylthio)benzenemethanol;4-(Phenylthio)Benzyl Chloride;parabenzenethioylbenzenemethylol;Benzenemethanol, 4-(phenylthio)-;(4-Phenylsulfanylphenyl)Methanol;(4-(chloromethyl)phenyl)(phenyl)sulfane
CBNumber:
CB0877350
Molecular Formula:
C13H12OS
Molecular Weight:
216.3
MDL Number:
MFCD04108413
MOL File:
6317-56-2.mol
MSDS File:
SDS
Last updated:2026-05-27 22:58:23

p-(phenylthio)benzyl alcohol Properties

Melting point 46-48°C
Boiling point 390.2±25.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 14.26±0.10(Predicted)
color Pale Beige to Light Beige
InChI InChI=1S/C13H12OS/c14-10-11-6-8-13(9-7-11)15-12-4-2-1-3-5-12/h1-9,14H,10H2
InChIKey PGOAWMRWDZJQTB-UHFFFAOYSA-N
SMILES C1(CO)=CC=C(SC2=CC=CC=C2)C=C1
FDA UNII TMD9BW7WU5

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

p-(phenylthio)benzyl alcohol price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-P336975-25G 4-(Phenylthio)benzyl Alcohol 6317-56-2 25g $122 2026-06-03 Buy
Usbiological 019609 4-(Phenylthio)benzyl Alcohol 6317-56-2 100mg $418 2026-06-03 Buy
Biosynth FP27006 4-(Phenylthio)benzyl alcohol 6317-56-2 10g $150 2026-06-04 Buy
Synthonix P56795 (4-(Phenylthio)phenyl)methanol 98% 6317-56-2 250mg $10 2026-05-06 Buy
Synthonix P56795 (4-(Phenylthio)phenyl)methanol 98% 6317-56-2 1g $11 2026-05-06 Buy
Product number Packaging Price Buy
TRC-P336975-25G 25g $122 Buy
019609 100mg $418 Buy
FP27006 10g $150 Buy
P56795 250mg $10 Buy
P56795 1g $11 Buy

p-(phenylthio)benzyl alcohol Chemical Properties, Uses, Production

Chemical Properties

Pale Beige Solid

Uses

An impurity of Fenticonazole nitrate (F279250), a new potent antimycotic compound.

Synthesis

4-(PHENYLTHIO)BENZALDEHYDE

1208-88-4

p-(phenylthio)benzyl alcohol

6317-56-2

The general procedure for the synthesis of p-phenylthiobenzyl alcohol from 4-phenylthiobenzaldehyde: 4-phenylthiobenzaldehyde and methanol were added to a reaction flask, and sodium borohydride was added in batches under stirring conditions, and the reaction mixture was naturally warmed up to 55 °C due to exotherm. The reaction was monitored by thin-layer chromatography (Expanding Agent: hexane/ethyl acetate=10:1) and took about 1 hour to complete. At the end of the reaction, the pH was adjusted to 6 by dropwise addition of hydrochloric acid and the reaction mixture was filtered. The filtrate was concentrated to dryness under reduced pressure (pressure 1330 Pa, temperature 45 °C) and methanol was recovered to give a viscous residue. To the residue was added an appropriate amount of dichloromethane, and the resulting mixture was washed with water until neutral and then dried with anhydrous sodium sulfate. The dried mixture was filtered and the filtrate was concentrated under reduced pressure (pressure 1720 Pa, temperature 25°C) to recover methylene chloride. After the concentrate was cooled to room temperature, a light yellow solid product was precipitated.

References

[1] Journal of Medicinal Chemistry, 2006, vol. 49, # 17, p. 5217 - 5225
[2] Patent: CN107652238, 2018, A. Location in patent: Paragraph 0022; 0023
[3] Patent: CN107573288, 2018, A. Location in patent: Paragraph 0015; 0023
[4] Chemical Communications, 2009, # 7, p. 827 - 829
[5] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 12, p. 3708 - 3712

139-66-2
6317-56-2
Synthesis of p-(phenylthio)benzyl alcohol from Diphenyl sulfide
Global Suppliers ( 170)
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Beijing Isomersyn Technology CO;LTD 010-82954736 13391601435 sales@isomersyn.com China 3294 57

View Latest Price from p-(phenylthio)benzyl alcohol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
p-(phenylthio)benzyl alcohol  pictures 2025-04-04 p-(phenylthio)benzyl alcohol
6317-56-2
1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
p-(phenylthio)benzyl alcohol pictures 2019-07-06 p-(phenylthio)benzyl alcohol
6317-56-2
$1.00 1kg 98%min Career Henan Chemical Co

p-(phenylthio)benzyl alcohol Spectrum

NSC 43060 (4-Phenylsulfanylphenyl)Methanol p-(phenylthio)benzyl alcohol 4-(Phenylthio)Benzyl Chloride (4-(chloromethyl)phenyl)(phenyl)sulfane 4-(Phenylthio)benzenemethanol Einecs 228-658-6 (4-(Phenylthio) p-(Phenylthio)benzyl alcohol (Fenticonazole nitrate INT) Benzenemethanol, 4-(phenylthio)- parabenzenethioylbenzenemethylol 6317-56-2 Aromatics Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds