perimetazine
- CAS No.
- 13093-88-4
- Chemical Name:
- perimetazine
- Synonyms
- RP-9159;RP 9159;Leptryl;AN-1317;AN 1317;perimetazine;1-[3-(2-methoxyphenothiazin-10-yl)-2-methylpropyl]piperidin-4-ol;1-(3-(2-Methoxy-10H-phenothiazin-10-yl)-2-methylpropyl)piperidin-4-ol;4-Piperidinol, 1-[3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]-
- CBNumber:
- CB0936936
- Molecular Formula:
- C22H28N2O2S
- Molecular Weight:
- 384.541
- MDL Number:
- MFCD00867994
- MOL File:
- 13093-88-4.mol
| Melting point | 137-138° |
|---|---|
| Boiling point | 569.1±50.0 °C(Predicted) |
| Density | 1.0944 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| pka | 14.87±0.20(Predicted) |
| FDA UNII | 2R880S54IS |
perimetazine price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P287000 | Perimethazine | 13093-88-4 | 250mg | $165 | 2021-12-16 | Buy |
| TRC | P287000 | Perimethazine | 13093-88-4 | 2.5g | $1320 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 61034 | Perimethazine | 13093-88-4 | 2.5g | $2200 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0012224 | PERIMETAZINE 95.00% | 13093-88-4 | 5MG | $498.87 | 2021-12-16 | Buy |
perimetazine Chemical Properties,Uses,Production
Originator
Leptryl ,Roger Bellon, France,1970
Uses
Perimethazine, is a novel Antipsychotic drug. It has shown to cause sedation, hypothermia, muscle relaxation, and other signs of central depression in rabbits.
Definition
ChEBI: Perimetazine is a member of phenothiazines.
Manufacturing Process
A solution of 3-methoxy-10-(3-chloro-2-methylpropyl)phenthiazine (9.65 grams) and 4-hydroxypiperidine (6.1 grams) in xylene (10 cc) is heated under reflux for 5 hours. After cooling the mixture is diluted with ether (60 cc) and the basic compounds are extracted by agitation with water (30 cc) and 4 N hydrochloric acid (20 cc). The aqueous acid phase is made alkaline with 4 N sodium hydroxide solution (23 cc) and the liberated base is extracted with ether. The ethereal solution is washed with water (60 cc) and dried over sodium sulfate. Finally the solvent is distilled off on a water-bath.
The solid residue obtained is recrystallized from a mixture (15:85) of benzene and cyclohexane and there is obtained 3-rnethoxy-10-[2-methyl-3-(4hydroxy-1-piperidyl)-propyl]-phenthiazine (5.7 grams) as a white crystalline powder, MP 137°-138°C.
Therapeutic Function
Tranquilizer
perimetazine Preparation Products And Raw materials
perimetazine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19905 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jk.info@jkchemical.com | China | 96815 | 76 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57422 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24863 | 58 |
| Santa Cruz Biotechnology Inc | 60936350 | scbt@scbt.com | China | 222068 | 58 |
View Lastest Price from perimetazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | Perimetazine
13093-88-4
|
US $1520.00-2500.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Perimetazine
13093-88-4
- US $1520.00-2500.00 / mg
- TargetMol Chemicals Inc.