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Azaphilone-9

CAS No.
1448460-87-4
Chemical Name:
Azaphilone-9
Synonyms
Azaphilone-9;6H-2-Benzopyran-6,8(7H)-dione, 7-(acetyloxy)-5-bromo-3-[(1E,3E,5S)-3,5-dimethyl-1,3-heptadien-1-yl]-7-methyl-
CBNumber:
CB09615799
Molecular Formula:
C21H23BrO5
Molecular Weight:
435.31
MDL Number:
MOL File:
1448460-87-4.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:31

Azaphilone-9 Properties

Boiling point 498.0±45.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)

Azaphilone-9 Chemical Properties, Uses, Production

Uses

Azaphilone-9 (AZA-9) is an inhibitor of HuR-ARE RNA interaction (IC50=1.2 μM) by binding RNA-binding protein Hu antigen R (HuR). The HuR-RNA interactions stabilize many oncogenic mRNAs in tumors. Thus Azaphilone-9 potentially inhibit cancer cell growth and progression[1].

References

[1] Kaur K, et al. The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro. PLoS One. 2017 Apr 17;12(4):e0175471. DOI:10.1371/journal.pone.0175471

Azaphilone-9 Preparation Products And Raw materials

Raw materials

Preparation Products

Azaphilone-9 Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
Azaphilone-9 6H-2-Benzopyran-6,8(7H)-dione, 7-(acetyloxy)-5-bromo-3-[(1E,3E,5S)-3,5-dimethyl-1,3-heptadien-1-yl]-7-methyl- 1448460-87-4