ChemicalBook >> CAS DataBase List >>1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro-

1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro-

1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- structure

CAS No.: 129700-44-3

Chemical Name:: 1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro-

Synonyms: Ac-Atovaquone;1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro-

CBNumber:: CB09787359

Molecular Formula:: C24H21ClO4

Molecular Weight:: 408.87

MDL Number:

MOL File:: 129700-44-3.mol

Last updated:2025-04-18 09:51:31

Request For Quotation

1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- Properties

Melting point	163.1 °C(Solv: ethanol (64-17-5))
Boiling point	557.9±50.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Predicted)

1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- Chemical Properties,Uses,Production

Uses

Ac-Atovaquone is a potent cytochrome bc1 inhibitor and also is an ester-linked acetyl derivative of atovaquone (HY-13832). Ac-Atovaquone has the potential for the research of malaria[1][1][2].

References

[1] Siqueira-Neto JL, et al. Antimalarial drug discovery: progress and approaches. Nat Rev Drug Discov. 2023 Oct;22(10):807-826. doi: 10.1038/s41573-023-00772-9. Epub 2023 Aug 31. Erratum in: Nat Rev Drug Discov. 2024 Nov;23(11):880.
[2] El Gaaloul M, et al. Chemoprevention of malaria with long-acting oral and injectable drugs: an updated target product profile. Malar J. 2024 Oct 18;23(1):315. DOI:10.1186/s12936-024-05128-1

1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- Preparation Products And Raw materials

Raw materials

Preparation Products

1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol	400-821-0310 15002144251	xuexiang.shao@tsbiochem.com	China	29128	58

Supplier	Advantage
TargetMol	58

1,4-Naphthalenedione, 2-(acetyloxy)-3-[trans-4-(4-chlorophenyl)cyclohexyl]-1,4-dihydro- Ac-Atovaquone 129700-44-3