Fosciclopirox
- CAS No.
- 1380539-06-9
- Chemical Name:
- Fosciclopirox
- Synonyms
- CPX-POM;Fosciclopirox;Fosciclopirox, 10 mM in DMSO;γ-secretase,Fosciclopirox,Gamma secretase,Inhibitor,inhibit;2(1H)-Pyridinone, 6-cyclohexyl-4-methyl-1-[(phosphonooxy)methoxy]-;((6-Cyclohexyl-4-methyl-2-oxopyridin-1(2H)-yl)oxy)methyl dihydrogen phosphate
- CBNumber:
- CB09926569
- Molecular Formula:
- C13H20NO6P
- Molecular Weight:
- 317.27
- MDL Number:
- MFCD34578234
- MOL File:
- 1380539-06-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 484.8±55.0 °C(Predicted) |
|---|---|
| Density | 1.38±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : 100 mg/mL (315.19 mM; Need ultrasonic) |
| pka | 1.68±0.10(Predicted) |
| form | Solid |
| color | Off-white to light yellow |
| FDA UNII | G8FR269QPQ |
Fosciclopirox price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0116368 | Fosciclopirox 99.66% | 1380539-06-9 | 5mg | $108 | 2026-06-04 | Buy |
| ChemScene | CS-0116368 | Fosciclopirox 99.66% | 1380539-06-9 | 10mg | $184 | 2026-06-04 | Buy |
| ChemScene | CS-0116368 | Fosciclopirox 99.66% | 1380539-06-9 | 25mg | $379 | 2026-06-04 | Buy |
| ChemScene | CS-0116368 | Fosciclopirox 99.66% | 1380539-06-9 | 50mg | $596 | 2026-06-04 | Buy |
| ChemScene | CS-0116368 | Fosciclopirox 99.66% | 1380539-06-9 | 100mg | $1029 | 2026-06-04 | Buy |
Fosciclopirox Chemical Properties, Uses, Production
Uses
Fosciclopirox suppresses growth of urothelial cancer by targeting the γ-secretase complex. Fosciclopirox selectively delivers the active metabolite, Ciclopirox (CPX), to the entire urinary tract[1][2]. Ciclopirox has anticancer activity in a number of solid and hematologic malignancies.
References
[1] Weir SJ, et al. Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting the γ-secretase complex. Cell Death Dis. 2021 May 31;12(6):562. DOI:10.1038/s41419-021-03836-z
[2] Weir SJ, Wood R, Schorno K, Brinker AE, Ramamoorthy P, Heppert K, Rajewski L, Tanol M, Ham T, McKenna MJ, McCulloch W, Dalton M, Reed GA, Jensen RA, Baltezor MJ, Anant S, Taylor JA 3rd. Preclinical Pharmacokinetics of Fosciclopirox, a Novel Treatment of Urothelial Cancers, in Rats and Dogs. J Pharmacol Exp Ther. 2019 Aug;370(2):148-159. DOI:10.1124/jpet.119.257972
Fosciclopirox Preparation Products And Raw materials
Raw materials
Preparation Products
Fosciclopirox Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9787 | 55 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Beijing Boorsen Biotechnology Co., Ltd | 400-901-9800 18611424007 | cis@bioss.com.cn | China | 9185 | 58 |
View Latest Price from Fosciclopirox manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-03 | Fosciclopirox
1380539-06-9
|
$48.00-173.00 | 99.65% | 10g | TargetMol Chemicals Inc. |
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- Fosciclopirox
1380539-06-9
- $48.00-173.00
- 99.65%
- TargetMol Chemicals Inc.
